Impact of buttermilk consumption on plasma lipids and surrogate markers of cholesterol homeostasis in men and women

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 23, Issue 12, 2013, Pages 1255-1262

  Conway, V ^a   Couture, P ^a,b   Richard, C ^a   Gauthier, S F ^a   Pouliot, Y ^a   Lamarche, B ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b University Laval   (Canada)

Author keywords

Buttermilk; Cholesterol homeostasis; Milk polar lipids; Plasma lipids; Sphingomyelin

Indexed keywords

CHOLESTEROL; LATHOSTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; SITOSTEROL; SUBTILISIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; BUTTERMILK; CONTROLLED STUDY; CROSSOVER PROCEDURE; DAIRY PRODUCT; DIETARY COMPLIANCE; DISEASE MARKER; DOUBLE BLIND PROCEDURE; FEMALE; FOOD INTAKE; HOMEOSTASIS; HUMAN; HUMAN EXPERIMENT; LIPID BLOOD LEVEL; MALE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR;

ANIMALIA;

APOB; APOLIPOROTEIN-B; BMI; BODY MASS INDEX; BUTTERMILK; C; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASE; CDV; CHD; CHOLESTEROL; CHOLESTEROL HOMEOSTASIS; CORONARY HEART DISEASE; CRP; FA; FATTY ACIDS; FFQ; FOLLICLE-STIMULATING HORMONE; FOOD-FREQUENCY QUESTIONNAIRE; FSH; MFGM; MILK FAT GLOBULE MEMBRANE; MILK POLAR LIPIDS; PCSK9; PLASMA LIPIDS; PROTEIN CONVERTASE SUBTILISIN KEXIN-9; SATURATED FATTY ACIDS; SFA; SL; SM; SPHINGOLIPIDS; SPHINGOMYELIN; TG; TRIACYLGLYCEROL;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; CHOLESTEROL; CHOLESTEROL, LDL; CROSS-OVER STUDIES; CULTURED MILK PRODUCTS; DOUBLE-BLIND METHOD; FEMALE; HOMEOSTASIS; HUMANS; INTESTINAL ABSORPTION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; REGRESSION ANALYSIS; RISK ASSESSMENT; RISK FACTORS; YOUNG ADULT;

EID: 84888836572     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2013.03.003     Document Type: Article

References (29)

1. Clark L.T. Treating dyslipidemia with statins: the risk-benefit profile. Am Heart J 2003, 145:387-396.
2. Ward S., Lloyd Jones M., Pandor A., Holmes M., Ara R., Ryan A., et al. A systematic review and economic evaluation of statins for the prevention of coronary events. Health Technol Assess (Winch, Eng) 2007, 11:1-160. [iii-iv].
3. Ros E. Intestinal absorption of triglyceride and cholesterol. Dietary and pharmacological inhibition to reduce cardiovascular risk. Atherosclerosis 2000, 151:357-379.
4. Jones P.J.H., AbuMweis S.S. Phytosterols as functional food ingredients: linkages to cardiovascular disease and cancer. Curr Opin Clin Nutri Metab Care 2009, 12:147-151. 10.1097/MCO.0b013e328326770f.
5. Third report of the national cholesterol education program (NCEP) expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation December 17, 2002, 106(25):3143.
6. Dawson P.A., Rudel L.L. Intestinal cholesterol absorption. Curr Opin Lipidol 1999, 10:315-320.
7. Conway V., Gauthier S.F., Pouliot Y. Effect of cream pasteurization, microfiltration and enzymatic proteolysis on invitro cholesterol-lowering activity of buttermilk solids. Dairy Sci Technol 2010, 90:449-460.
8. Seidah N.G. PCSK9 as a therapeutic target of dyslipidemia. Expert Opin Ther Targets 2009, 13:19-28.
9. Nissinen M.J., Gylling H., Miettinen T.A. Responses of surrogate markers of cholesterol absorption and synthesis to changes in cholesterol metabolism during various amounts of fat and cholesterol feeding among healthy men. Br J Nutr 2008, 99:370-378.
10. Simonen P., Gylling H., Miettinen T.A. The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes. Atherosclerosis 2008, 197:883-888.
11. Goulet J., Nadeau G., Lapointe A., Lamarche B., Lemieux S. Validity and reproducibility of an interviewer-administered food frequency questionnaire for healthy French-Canadian men and women. Nutr J 2004, 3:13.
12. Labonté M.-È., Couture P., Paquin P., Chouinard Y., Lemieux S., Lamarche B. Comparison of the impact of trans fatty acids from ruminant and industrial sources on surrogate markers of cholesterol homeostasis in healthy men. Mol Nutr Food Res 2011, 55:S241-S247.
13. Miettinen T.A., Tilvis R.S., Kesaniemi Y.A. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol 1990, 131:20-31.
14. Lohman T.G., Roche A.F., Martorell R. Anthropometric standardization reference manual 1988, Human Kinetics Books, Champaign, Illinois. T.G. Lohman, A.F. Roche, R. Martorell (Eds.).
15. Motard-Bélanger A., Charest A., Grenier G., Paquin P., Chouinard Y., Lemieux S., et al. Study of the effect of trans fatty acids from ruminants on blood lipids and other risk factors for cardiovascular disease. Am J Clin Nutr 2008, 87:593-599.
16. Ohlsson L., Burling H., Duan R.D., Nilsson A. Effects of a sphingolipid-enriched dairy formulation on postprandial lipid concentrations. Eur J Clin Nutr 2010, 64:1344-1349.
17. Ohlsson L., Burling H., Nilsson Å. Long term effects on human plasma lipoproteins of a formulation enriched in butter milk polar lipid. Lipids Health Dis 2009, 8:1-12.
18. Thompson L.U., Jenkins D.J., Amer M.A., Reichert R., Jenkins A., Kamulsky J. The effect of fermented and unfermented milks on serum cholesterol. Am J Clin Nutr 1982, 36:1106-1111.
19. Schaefer E., Lamon-Fava S., Ausman L., Ordovas J., Clevidence B., Judd J., et al. Individual variability in lipoprotein cholesterol response to National Cholesterol Education Program Step 2 diets. Am J Clin Nutr 1997, 65:823-830.
20. Gupta A.K., Savopoulos C.G., Ahuja J., Hatzitolios A.I. Role of phytosterols in lipid-lowering: current perspectives. QJM 2011, 104:3018.
21. Duivenvoorden I., Voshol P.J., Rensen P.C., van Duyvenvoorde W., Romijn J.A., Emeis J.J., et al. Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice. Am J Clin Nutr 2006, 84:312-321.
22. Dewettinck K., Rombaut R., Thienpont N., Le T.T., Messens K., Van Camp J. Nutritional and technological aspects of milk fat globule membrane material. Int Dairy J 2008, 18:436-457.
23. Nyberg L., Duan R.-D., Nilsson Å. A mutual inhibitory effect on absorption of sphingomyelin and cholesterol. J Nutr Biochem 2000, 11:244-249.
24. Eckhardt E.R.M., Wang D.Q.-H., Donovan J.M., Carey M.C. Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers. Gasteroenterology 2002, 122:948-956.
25. Noh S.K., Koo S.I. Egg sphingomyelin lowers the lymphatic absorption of cholesterol and alpha-tocopherol in rats. J Nutri 2003, 133:3571-3576.
26. Feng D., Ohlsson L., Ling W., Nilsson Å., Duan R.-D. Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 Cells. Dig Dis Sci 2010, 55:3377-3383.
27. Garmy N., Taïeb N., Yahi N., Fantini J. Interaction of cholesterol with sphingosine. J Lipid Res 2005, 46:36-45.
28. Chan D.C., Lambert G., Barrett P.H.R., Rye K.-A., Ooi E.M.M., Watts G.F. Plasma proprotein convertase subtilisin/kexin type 9: a marker of LDL apolipoprotein B-100 catabolism?. Clin Chem 2009, 55:2049-2052.
29. Matthan N.R., Raeini-Sarjaz M., Lichtenstein A.H., Ausman L.M., Jones P.J.H. Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women. Lipids 2000, 35:1037-1044.