Minor hemoglobins HbA2 and HbF associate with disease severity in bipolar disorder with a likely protective role of HbA2 against post-partum episodes

Journal of Affective Disorders

Volumn 151, Issue 1, 2013, Pages 405-408

  Ince, Bahri ^a   Guloksuz, Sinan ^b,c   Altinbaş, Kürat ^d   Oral, Esat Timuçin ^e   Alpkan, Latif Ruhat ^f   Altinoz, Meric A ^g  

^a Sanliurfa Research and Training Hospital Sanliurfa   (Turkey)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ÇANAKKALE ONSEKIZ MART UNIVERSITY   (Turkey)

^e ISTANBUL COMMERCE UNIVERSITY   (Turkey)

^f ISTANBUL GELISIM UNIVERSITY   (Turkey)

^g HALIC UNIVERSITY   (Turkey)

Author keywords

Bipolar disorder; Episode density; Fetal hemoglobin; Hemoglobin A2; Intermittent hypoxia; Postpartum episode

Indexed keywords

HEMOGLOBIN A2; HEMOGLOBIN F;

ADULT; ARTICLE; BIPOLAR I DISORDER; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEMOGLOBIN BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMITTENT HYPOXIA; MAJOR CLINICAL STUDY; MALE; PREGNANCY; PRIORITY JOURNAL; PROTEIN FUNCTION; PUERPERIUM;

BIPOLAR DISORDER; EPISODE DENSITY; FETAL HEMOGLOBIN; HEMOGLOBIN A2; INTERMITTENT HYPOXIA; POSTPARTUM EPISODE;

ADULT; ANOXIA; BIPOLAR DISORDER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; FETAL HEMOGLOBIN; HEMOGLOBIN A2; HUMANS; MALE; POSTPARTUM PERIOD; PREGNANCY; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX;

EID: 84888639256     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2013.06.042     Document Type: Article

References (41)

1. Aessopos, A., Kati, M., Tsironi, M., Polonifi, E., Farmakis, D., 2006. Exchange blood transfusions for the treatment of leg ulcerations in thala ssemia intermedia. Haematologica 91 (5 Suppl), ECRII
2. BackstrOm, T., Andersson, it, nndree, I., Birzniece, V., Bixo, M., BjOrn, L., Haage, D., lsaksson, M., Johansson, I.M., Lindblad, C., Lundgren, R, Nyberg, S., Odmark, IS., Stromberg, J., Sundstrom-Poromaa, L., Turkmen, S., Wahlstrom, C., Wang, M., Wihlback, AC., Zhu, D., Zingmark, E., 2003. Pathogenesis in menstrual cycle-linked CNS disorders. Annals of the New York Academy of Sciences 1007, 42-53
3. Biagioli, M., Pinto, M., Cesselli, D., Zaninello, M., Lazarevic, D., Roncaglia, R, Simone, R., Vlachouli, C., Plessy, C., Bertin, N., Beltrami, A., Kobayashi, IC, Gallo, V., Santoro, C., Ferrer, 1 ., Rivella, S., Beltrami, C.A., Carninci, R, Raviola, E., Gustincich, S., 2009. unexpected expression of alpha-and beta-globin in mesencephalic dopaminergic neurons and glial cells. Proceedings of the National Academy of Sciences of the uni ted States of America 106, 15454-15459
4. Bickler, RE, Donohoe, RH., 2002. Adaptive responses of vertebrate neurons to hypoxia. Journal of Experimental Biology 205, 3579-3586
5. Bigham, A ., Bauchet, M., Pinto, D., Mao, X., Akey,J.M., Mei, R., Scherer, S.W.,Julian, C. C., Wilson, M.J., Lopez Herráez, D., Brutsaert, T., Parra, E.J., Moore, I.G., Shriver, M.D., 2010. Identifying si gnatures of natural selection in Tibetan and Andean populations using dense genome scan data. PLoS Genetics 6, 9
6. Bocchetta, A., 2005. Heterozygous beta-thalassaemia as a susceptibility factor in mood disorders: Excessiv e prevaLence in bipolar patients. Clinical PractIce and Epidemiology in Mental Health 1, 6
7. Bocchetta, A., Del Zompo, M., 1990. Bipolar affective disorder and heterozygous beta-thalassaemia. American Journal of Psychiatry 147, 1094
8. Bozdar, M., Ahmed, S., Anwar, J., 2010. Relative protection from ischaemic heart disease in beta-thalassaemia carriers. Journal of the College of Physicians and Surgeons Pakistan 20, 653-656
9. Brett, A., Dunn, R, 1998. Bipolar affective disorder and thalassaemia minor. Australian and New Zealand Journal of Psychiatry 32, 141
10. Campbell, ICL, Storz, J.E, Si gnore, A.V., Moriyama, H., Catania, LCC., Payson, AR, Bonaventura, J., Stetefeld, J., Weber, R.E., 2010. Molecular basis of a novel adaptation to hypoxic-hypercapnia in a strictly fossorial mole. BMC Evolutionary Biology 10, 214
11. Ciprian-Ollivier, J., Albin, J., de Lopez Mato, A.M., 1991. Talasemiay enfermedad bipolar. Alcmeon 4, 547-55S
12. Damianova, L, Popnikolov, S., Pencheva, B., Angelova, A., 1989. cbanges in the hemoglobin A2 level of patients with ischemic heart disease. Vutr Boles 28, 28-31
13. Damyanova, L, 1989. Electrophoretic HbA2 assessment in ischemic heart disease. Z Med Lab Diagn 30, 437-439
14. Diringer, M.N., 2008. Hyperoxia: Good or bad for the injured brain? Current Opinion in Critical Care 14, 167-171
15. Giambona, A., Passarello, C., Renda, D., Maggio, A., 2009 . The significance of the hemoglobin A(2) value in screening for hemoglobinopathies. Clinical Biochemistry 42, 1786-1796
16. Gonul, AS., Coburn, IC, Kula, M., 2009. Cerebral blood flow, metabolic, recepto r, and transporter changes in bipolar disorder: The role of PET and SPECT studies. International Review of Psychiatry 21, 323-33S
17. Hankeln, T., Wystub, S., Laufs, T., Schmidt, M., Gerlach, E, Saaler-Rei nhardt, S., Reuss, S., Burmester, T., 2004. The cellular and subcellular localization of neuroglobin and cytoglobin-a clue to their function? IUBMB Life 56, 671-679
18. Harada, H., Nakajima, T., Inazawa, J., Abe, T., 1995. Bipolar affective disorder associated with B-thalassemia minor. Biological Psychiatry 37, 477-479
19. Huang, MC., Wang, YB., Chan, C.H., 2008. Estrogen-progesterone combination for treatment-refractory post-partum mania. Psychiatry and Clinical Neurosciences 62, 126
20. Jaeger, J., Vieta, E., 2007. Functional outcome and disability in bipolar disorders: Ongoing research and future directions. Bipolar Disord 9, 1-2
21. Joffe, R.T., Horvath, Z., Tarvydas, L., 1986. Bipolar affective disorder and thalassemia minor. American Journal of Psychiatry 143, 933
22. Kato, T., 2001. Molecular genetics of bipolar disorder. Neuroscience Research 40, 105-113
23. Kulkarni, J., Garland, ICA., Scaffidi, A., Headey, B., Anderson, R, de Castella, A., Fitzgerald, R, Davis, SR., 2006. A pilot study of hormone modulation as a new treatment for mania in women with bipolar affective disorder. Psychoneuroendocrinology 31, 543-547
24. Lippi, G., Carta, M.R., Salvagno, G.L, Bellorio, F , Montagnana, lvi., ornau, U., uuiai, G.C., 2008. Separation of haemoglobin HbE and HbA by the fully automated, high-pressure liquid chromatography Tosoh HLC-723 G7 analyzer. International Journal of Laboratory Hematology 30, 432-436
25. Matsuda, M., Sakamoto, N., Fukumaki, Y., 1992. Delta-thalassemia caused by disruption of the site for an erythroid-specific transcription factor, GATA-1, in the delta-globin gene promoter. Blood 80, 1347-1351
26. Mclnnis. MG. Dick. DM. Wilbur. VI. Avramopoulos. D. MacKinnon. DF. Simpson. SG. Potash, JB, Edenberg, HJ, Bowman, ES, McMahon, FJ, Smiley, C, Chellis, JL, Huo, Y, Diggs, T, Meyer, ET, Miller, M, Matteini, AT, Rau, NL, DePaulo, JR. Gershon, ES, Badner, JA, RIce, JP, Goate, AM, Detera-Wadleigh, SD, Nurnberger, JI, Reich, T, Zandi, PP, Foroud, TM, 2003. Genome-wide scan and conditi onal analysis in bipolar disorder: Evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees. Biological Psychiatry 54, 1265-1273
27. Paleari, R., Cannata, M., Let o, F, Maggio, A., Demartis, FR., Desogus, ME, Galanello, R., Mosca, A., 2005. Analytical evaluation of the Tosoh HLC-723 G7 automated HPLC analyzer for hemoglobin A2 and F determination. Clinical Biochemistry 38, 159-16S
28. Perry, R.T., Gearhart, D.A., Wiener, H.W., Harrell, LE., Barton, J.C., Kutlar, A., Kutlar, F, Ozcan, O., Go, R.C., Hill, W.D., 2008. Hemoglobin binding to A beta and HBG2 SNP association suggest a role in Alzheimer 's disease. Neurobiology of Aging 29, 185-191
29. Ranney, H.M., Lam, R., Rosenberg, G., 1993. Some properties of hemoglobin A2. American Journal of Hematology 42, 107-111
30. Reinares, M., Papachristou, E., Harvey, R, Mar Bonnin, C., Sánchez-Moreno, J., Torrent, C., Ayuso-Mateos, J.L, Ploubidis, G.B., Vieta, E., Frangou, S., 2013. Towards a clinical staging for bipolar disorder: Defining patient subtypes based on functional outcome. Journal of Affective Disorders 144, 65-71
31. Risso, A., Fabbro, D., Damante, G., Antonutto, G., 2012. Expression of fetal hemoglobin in adult humans exposed to high altitude hypoxia. Blood Cells , Molecules and Diseases 48, 147-153
32. Sachs, G.S., Thase, M.E., Otto, M.W., Bauer, M., Miklowitz, D., Wisniewski, SR., Lavori, R, Lebowitz, B., Rudorfer, M., Frank, E., Nierenberg, A. A., Fava, M., Bowden, C., Ketter, T., Marangell, L, Calabrese, J., Kupfer, D., Rosenbaum, J.E, 2003. Rationale, design, and methods of the systematic treatment enhancement program for bipolar disorder (STEP-BD). B iological Psychiatry 53, 1028-1042
33. Sen, U., Dasgupta, J., Choudhury, D., Datta, R, Chakrabarti, A., Chakrabarty, SB., Chakrabarty, A., Dattagupta, J.IC, 2004. Crystal structures of HbA2 and HbE and modeling of hemoglobin de lta 4: Interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb. Biochemistry 43, 12477-12488
34. Serretti, A., Mandelli, L, 2008. The genetics of bipolar disorder: Genome hot regions,' genes, new potential candidates and future directions. Molecular Psychiatry 13, 742-771
35. Da Silva Santos Duarte, A., Sales, T.S., Mengel, JO., Costa, FE, Saad, ST., 2002. Progesterone upregulates GATA-1 on erythroid progenitors cells in liquid culture. Blood Cells, Molecules and Diseases 29, 213-224
36. Singh, A.N., Maguire, J., 1988. Bipolar affective disorder and thalassaemia minor-a genetic linkage? The British Journal of Psychiatry 152, 581
37. Son, YU.A., 1979. Quantitative estimation of hemoglobin and its fractions in permanent mountain dwellers in the Tyan'-Shan' and Pamir. Human Physiology 5, 208-210.
38. Spritz, R.A., Giebel, LB., 1988. The structure and evolution of the spider monkey delta-globin gene. Molecular Biology and Evolution 5, 21-29
39. Tirpan, IC, Ozerdem, A., Tunca, L, Yazici, O., Oral, E.T., Kurt, E., Vahip, S., 2004. A computerized registry program for bipolar illness in Turkey. Journal of Affective Disorders 78 (suppl), 126-127
40. Wong, R, 2004. A hypothesis on the role of the electrical charge of haemoglobin in regulating the erythrocyte shape. Medical Hypotheses 62, 124-129
41. Zarubina, E.G., 2002. Structural alterations in erythrocyte membranes in patients with myocardial infarction. Voen Med Zh 323 (34-36), 96