The cellular and subcellular localization of neuroglobin and cytoglobin - A clue to their function?

IUBMB Life

Volumn 56, Issue 11-12, 2004, Pages 671-679

  Hankeln, Thomas ^a   Wystub, Sylvia ^a   Laufs, Tilmann ^a   Schmidt, Marc ^a   Gerlach, Frank ^a   Saaler Reinhardt, Sigrid ^a   Reuss, Stefan ^a   Burmester, Thorsten ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Cytoglobin; Neuroglobin; Neuron; Oxygen; Retina

Indexed keywords

CYTOGLOBIN; GLOBIN; NEUROGLOBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; CELL MATURATION; CELL TYPE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; ENERGY METABOLISM; EXTRACELLULAR MATRIX; FIBROBLAST; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; TISSUE DISTRIBUTION;

ANIMALS; FLUORESCENT ANTIBODY TECHNIQUE; GLOBINS; HUMANS; MICE; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; ORGAN SPECIFICITY;

EID: 17144430126     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/15216540500037794     Document Type: Conference Paper

References (45)

1. Dickerson, R. E., and Geis, I. (1983) Hemoglobin: Structure, function, evolution, and pathology. Benjamin/Cummings Publ. Co., CA, USA
2. Wittenberg, J. B., and Wittenberg, B. A. (2003) Myoglobin function reassessed. J. Exp. Biol. 206, 2011-2020.
3. Hankeln, T., Ebner, B., Fuchs, C. Gerlach, F., Haberkamp, M., Laufs, T., Roesner, A., Schmidt, M., Weich, B., Wystub, S., Saaler-Reinhardt, S., Reuss, S., Bolognesi, M., De Sanctis, D., Marden, M. C., Kiger, L., Dewilde, S., Moens, L., Nevo, E., Avivi, A., Weber, R. E., Fago, A., and Burmester, T. (2005) Neuroglobin and cytoglobin in search of their role in the vertebrate globin family. J. Inorg. Biochem. 99, 110-119.
4. Burmester, T., Weich, B., Reinhardt, S., and Hankeln, T. (2000) A vertebrate globin expressed in the brain. Nature 407, 520-523.
5. Burmester, T., Ebner, B., Weich, B., and Hankeln, T. (2002) Cytoglobin: A novel globin type ubiquitously expressed in vertebrate tissues. Mol. Biol. Evol. 19, 416-421.
6. Trent, J. T. 3rd, and Hargrove, M. S. (2002) A ubiquitously expressed human hexacoordinate haemoglobin. J. Biol. Chem. 277, 19538-19545.
7. Pesce, A., Dewilde, S., Nardini, M., Moens, L., Ascenzi, P., Hankeln, T., Burmester, T., and Bolognesi, M. (2003) Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity. Structure 11, 1087-1095.
8. de Sanctis, D., Dewilde, S., Pesce, A., Moens, L., Ascenzi, P., Hankeln, T., Burmester, T., and Bolognesi, M. (2004) Crystal structure of cytoglobin: The fourth globin type discovered in man displays heme hexa-coordination. J. Mol. Biol. 336, 917-927.
9. Dewilde, S., Kiger, L., Burmester, T., Hankeln, T., Baudin-Creuza, V., Aerts, T., Marden, M. C., Caubergs, R., and Moens, L. (2001) Biochemical characterization and ligand binding properties of neuroglobin, a novel member of the globin family. J. Biol. Chem. 276, 38949-38955.
10. Pesce, A., Bolognesi, M., Ascenzi, P., Bocedi, A., Dewilde, S., Moens, L., Hankeln, T., and Burmester, T. (2002) Neuroglobin and cytoglobin: Fresh blood for the vertebrate globin family. EMBO Rep. 3, 1146-1151.
11. Hamdane, D., Kiger, L., Dewilde, S., Green, B. N., Pesce, A., Uzan, J., Burmester, T., Hankeln, T., Bolognesi, M., Moens, L., and Marden, M. C. (2003) The redox state of the cell regulates the ligand binding affinity of human neuroglobin and cytoglobin. J. Biol. Chem. 278, 51713-51721.
12. Fordel, E., Geuens, E., Dewilde, S., Rottiers, P., Carmeliet, P., Grooten, J., and Moens, L. (2004) Cytoglobin expression is upregulated in all tissues upon hypoxia: An in vitro and in vivo study by quantitative real-time PCR. Biochem. Biophys. Res. Commun. 319, 342-348.
13. Schmidt, M., Gerlach, F., Avivi, A., Laufs, T., Wystub, S., Simpson, J. C., Nevo, E., Saaler-Reinhardt, S., Reuss, S., Hankein, T., and Burmester, T. (2004) Cytoglobin is a respiratory protein expressed in connective tissue and neurons that is up-regulated by hypoxia. J. Biol. Chem. 279, 8063-8069.
14. Wystub, S., Ebner, B., Fuchs, C., Weich, B., Burmester, T., and Hankeln, T. (2004) Interspecies comparison of neuroglobin, cytoglobin and myoglobin: sequence evolution and candidate regulatory elements. Cytogenet. Genome Res. 105, 65-78,
15. Mammen, P. P., Shelton, J. M., Goetsch, S. C., Williams, S. C., Richardson. J. A., Carry, M. G., and Garry, D. J. (2002) Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain. J. Histochem. Cytochem. 50, 1591-1598.
16. Sun, Y., Jin, K., Mao, X. O., Zhu, Y., and Greenberg, D. A. (2001) Neuroglobin is upregulated by and protects neurons from hypoxic-ischemic injury. Proc. Natl. Acad. Sci. USA 98, 15306-15311.
17. Sun, Y., Jin, K., Peel, A., Mao, X. O., Xie, L., and Greenberg, D. A. (2003) Neuroglobin protects the brain from experimental stroke in vivo. Proc. Natl. Acad. Sci. USA 100, 3497-3500.
18. Burmester, T., and Hankeln, T. (2004) Neuroglobin: A respiratory protein of the nervous system. News Phys. Sci. 19, 110-113.
19. Zhang, C., Wang, C., Deng, M., Li, L., Wang, H., Fan, M., Xu, W., Meng, F., Qian, L., and He, F. (2002) Full-length cDNA cloning of human neuroglobin and tissue expression of rat neuroglobin. Biochem. Biophys. Res. Commun. 290, 1411-1419.
20. Reuss, S., Saaler-Reinhardt, S., Weich, B., Wystub, S., Reus, M., Burmester, T., Hankeln, T. (2002) Expression analysis of mouse neuroglobin. Neuroscience 115, 645-656.
21. Wystub, S., Laufs, T., Schmidt, M., Burmester, T., Maas, U., Saaler-Reinhardt, S., Hankeln, T., and Reuss, S. (2003) Localisation of neuroglobin protein in the mouse brain. Neurosci. Lett. 346, 114-116.
22. Geuens, E., Brouns, I., Flamez, D., Dewilde, S., Timmermans, J. P., and Moens, L. (2003) A globin in the nucleus! J. Biol. Chem. 278, 30417-30420.
23. Fuchs, C., Heib, V., Kiger, L., Haberkamp, M., Roesner, A., Schmidt, M., Hamdane, D., Marden, M. C., Hankeln, T., and Burmester, T. (2004) Zebrafish reveals different and conserved features of vertebrate neuroglobin gene structure, expression pattern and ligand binding. J. Biol. Chem. 279, 24116-24122.
24. Kugelstadt, D., Haberkamp, M., Hankeln, T., and Burmester, T. (2004) Neuroglobin, cytoglobin, and a novel, eye-specific globin from chicken. Biochem. Biophys. Res. Commun. 325, 719-725.
25. Laufs, T., Wystub, S., Reuss, S., Burmester, T., Saaler-Reinhardt, S., and Hankeln, T. (2004) Neuron-specific expression of neuroglobin. Neurosci. Lett. 362, 83-86.
26. Wittenberg, J. B. (1992) Functions of cytoplasmic hemoglobins and myohemerythrin. Adv. Comp. Environm. Physiol. 13, 59-85.
27. Schmidt, M., Gießl, A., Laufs, T., Hankeln, T., Wolfrum, U., and Burmester, T. (2003) How does the eye breathe? Evidence for neuroglobin-mediated oxygen supply of the mammalian retina. J. Biol. Chem. 278, 1932-1935.
28. Nakatani, K., Okuyama, H., Shimahara, Y., Saeki, S., Kim, D. H., Nakajima, Y., Seki, S., Kawada, N., and Yoshizato, K. (2004) Cytoglobin/STAP, its unique localization in splanchnic fibroblast-Iike cells and function in organ fibrogenesis. Lab. Invest. 84, 91-101.
29. Kawada, N., Kristensen, D. B., Asahina, K., Nakatani, K., Minamiyama, Y., Seki, S. and Yoshizato, K. (2001) Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J. Biol. Chem. 276, 25318-25323.
30. Schmidt, M., Laufs, T., Reuss, S., Hankeln, T., and Burmester, T. (2005) Divergent distribution of cytoglobin and neuroglobin in the mammalian eye. Neurosci. Lett. 374, 207-211.
31. Tateaki, Y., Ogawa, T., Kawada, N., Kohashi, T., Arihiro, K., Tateno, C., Obara, M., and Yoshizato, K. (2004) Typing of hepatic nonparenchymal cells using fibulin-2 and cytoglobin/STAP as liver fibrogenesis-related markers. Histochem. Cell Biol. 122, 41-49.
32. Wakasugi, K., Nakano, T., and Morishima, I. (2003) Oxidized human neuroglobin acts as a heterotrimeric Galpha protein guanine nucleotide dissociation inhibitor. J. Biol. Chem. 278, 36505-36512.
33. Wakasugi, K., Nakano, T., and Morishima, I. (2004) Association of human neuroglobin with cystatin C, a cysteine proteinase inhibitor. Biochemistry 43, 5119-5125.
34. Wakasugi, K., Nakano, T., Kitatsuji, C., and Morishima, I. (2004) Human neuroglobin interacts with flotillin-1, a lipid raft microdomain-associated protein. Biochem. Biophys. Res. Commun. 318, 453-460.
35. Xu, W. L., Wang, C. L., Liao, Z. Y., Zhang, Y. L., Yu, L. H., Meng, F. W., Wang, X. X., Meng, F. W., Yin, Z. Y., Qian, L. J., and Zhang, C. G. (2003) Identification of interaction and interaction domains between neuroglobin and Na(+), K(+)-ATPase beta2 subunit. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35, 823-828.
36. Aronica, E., van Vliet, E. A., Hendriksen, E., Troost, D., Lopes da Silva, F. H., and Gorter, J. A. (2001) Cystatin C, a cysteine protease inhibitor, is persistently upregulated in neurons and glia in a rat model for mesial temporal lobe epilepsy. J. Neurosci. 14, 1485-1491.
37. Stuermer, C. A., Lang, D. M., Kirsch, F., Wiechers, M., Deininger, S. O., and Plattner, H. (2001) Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane defined by reggie-1 and -2. Mol. Biol. Cell. 12, 3031-3045.
38. Senner, V., Schmidtpeter, S., Braune, S., Puttmann, S., Thanos, S., Bartsch, U., Schachner, M., and Paulus, W. (2003) AMOG/beta2 and glioma invasion: does loss of AMOG make tumour cells run amok? Neuropathol. Appl. Neurobiol. 29, 370-377.
39. Herold, S., Fago, A., Weber, R. E., Dewilde, S., and Moens, L. (2004) Reactivity studies of the Fe(III) and Fe(II)NO forms of human neuroglobin reveal a potential role against oxidative stress. J. Biol. Chem. 279, 22841-22847.
40. Fago, A., Hundahl, C., Dewilde, S., Gilany, K., Moens, L., and Weber, R. E. (2004) Allosteric regulation and temperature dependence of oxygen binding in human neuroglobin and cytoglobin. Molecular mechanisms and physiological significance. J. Biol. Chem. 279, 44417-44426.
41. Neufeld, A. H., Shareef, S., and Pena, J. (2000) Cellular localization of neuronal nitric oxide synthase (NOS-1) in the human and rat retina. Comp. Neurol. 416, 269-275.
42. Reuss, S., and Riemann, R. (2000) Distribution and projections of nitric oxide synthase neurons in the rodent superior olivary complex. Microsc. Res. Tech. 51, 318-329.
43. Rodrigo, J., Alonso, D., Fernandez, A. P., Serrano, J., Richart, A., Lopez, J. C. Santacana, M., Martinez-Murillo, R., Bentura, M. L., Ghiglione, M., and Uttenthal, L. O. (2001) Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation. Brain Res. 909, 20-45.
44. Schmidt-Kastner, R., and Freund, T. F. (1991) Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40, 599-636.
45. Sokoloff, L. (1981) Localization of functional activity in the central nervous system by measurement of glucose utilization with radioactive deoxyglucose. J. Cereb. Blood Flow Metabol. 1, 7-36.