Advising patients on the use of non-herbal nutritional supplements during cancer therapy: A need for doctor-patient communication

Journal of Pain and Symptom Management

Volumn 46, Issue 6, 2013, Pages 887-896

  Ben Arye, Eran ^a,b   Polliack, Aaron ^c   Schiff, Elad ^d,e   Tadmor, Tamar ^d   Samuels, Noah ^f  

^a CLALIT HEALTH SERVICES   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d BNAI ZION MEDICAL CENTER   (Israel)

^e UNIVERSITY OF HAIFA   (Israel)

^f SHAARE ZEDEK MEDICAL CENTER   (Israel)

Author keywords

complementary alternative medicine; Dietary supplements; doctor patient communication; efficacy; integrative medicine; safety

Indexed keywords

ALPHA TOCOPHEROL; ANTHRACYCLINE; CISPLATIN; CYCLOSPORIN; FLUOROURACIL; GLUTAMINE; GLUTATHIONE; IRINOTECAN; LEVACECARNINE; MELATONIN; METHOTREXATE; OPIATE; OXALIPLATIN; PACLITAXEL; PLATINUM; PROBIOTIC AGENT; TAMOXIFEN; TAXANE DERIVATIVE;

ALTERNATIVE MEDICINE; ANALGESIA; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER THERAPY; COLORECTAL CANCER; DIARRHEA; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DISEASE SEVERITY; DOCTOR PATIENT RELATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; DRUG SAFETY; HEAD AND NECK CANCER; HUMAN; LUNG CANCER; NEOPLASM; NEUROTOXICITY; NONHUMAN; ORAL MUCOSITIS; OVARY CANCER; PAIN; PATIENT COUNSELING; PERIPHERAL NEUROPATHY; QUALITY OF LIFE; REVIEW; SCORING SYSTEM; SENSORY NEUROPATHY; SOLID TUMOR; STOMACH CANCER; SYMPTOM ASSESSMENT; SYSTEMATIC REVIEW;

COMPLEMENTARY ALTERNATIVE MEDICINE; DIETARY SUPPLEMENTS; DOCTOR-PATIENT COMMUNICATION; EFFICACY; INTEGRATIVE MEDICINE; SAFETY;

ANTINEOPLASTIC AGENTS; DIETARY SUPPLEMENTS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; INCIDENCE; MALE; NEEDS ASSESSMENT; NEOPLASMS; PATIENT EDUCATION AS TOPIC; PHYSICIAN-PATIENT RELATIONS; PREVALENCE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; TREATMENT OUTCOME;

EID: 84888638639     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2013.02.010     Document Type: Review

References (67)

1. G.H. Lyman Impact of chemotherapy dose intensity on cancer patient outcomes J Natl Compr Canc Netw 7 2009 99 108
2. N. Vapiwala, R. Mick, M.K. Hampshire, J.M. Metz, and A.S. DeNittis Patient initiation of complementary and alternative medical therapies (CAM) following cancer diagnosis Cancer J 12 2006 467 474
3. J.S. Yates, K.M. Musteian, and G.R. Morrow Prevalence of complementary and alternative medicine use in cancer patients during treatment Support Care Cancer 13 2005 806 811
4. C.S. Roberts, F. Baker, and D. Hann Patient-physician communication regarding use of complementary therapies during cancer treatment J Psychosoc Oncol 23 2005 35 60
5. U.S. Food and Drug Administration. Dietary Supplement Health and Education Act of 1994. Pub. L. No. 103-417. 103rd Congress. Oct. 25, 1994. Available from http://history.nih.gov/research/downloads/PL103-417.pdf. Accessed February 1, 2013.
6. D.M. Eisenberg, R.B. Davis, and S.L. Ettner Trends in alternative medicine use in the United States, 1990-1197: results of a follow-up national survey JAMA 280 1998 1569 1575
7. E. Ernst Prevalence of use of complementary/alternative medicine: a systematic review Bull World Health Org 78 2000 252 257
8. C.M. Velicer, and C.M. Ulrich Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review J Clin Oncol 26 2008 665 673
9. H. Greenlee, M.D. Gammon, and P.E. Abrahamson Prevalence and predictors of antioxidant supplement use during breast cancer treatment: the Long Island Breast Cancer Study Project Cancer 115 2009 3271 3282
10. L.M. Ferrucci, R. McCorkle, T. Smith, K.D. Stein, and B. Cartmel Factors related to the use of dietary supplements by cancer survivors J Altern Complement Med 15 2009 673 680
11. S.M. Rausch, F. Winegardner, and K.M. Kruk Complementary and alternative medicine: use and disclosure in radiation oncology community practice Support Care Cancer 19 2011 521 529
12. A. Thomas-Schoemann, J. Alexandre, and C. Mongaret Use of antioxidant and other complementary medicine by patients treated by antitumor chemotherapy: a prospective study Bull Cancer 98 2011 645 653
13. S.M. Giveon, N. Liberman, S. Klang, and E. Kahan Are people who use 'natural drugs' aware of their potentially harmful side effects and reporting to family physician? Patient Educ Couns 53 2004 5 11
14. J. Gulla, and A.J. Singer Use of alternative therapies among emergency department patients Ann Emerg Med 35 2000 226 227
15. P.M. Barnes, E. Powell-Griner, K. McFann, and R.L. Nahin Complementary and alternative medicine use among adults: Unites States, 2004 Adv Data 343 2004 1 20
16. M. Hastings-Tolsma, and M. Terada Complementary medicine use by nurse midwives in the U.S. Complement Ther Clin Pract 15 2009 212 219
17. A.H. Lee, S.E. Ingraham, M. Kopp, M.I. Foraida, and A.R. Jazieh The incidence of potential interactions between dietary supplements and prescription medications in cancer patients at a Veterans Administration Hospital Am J Clin Oncol 29 2006 178 182
18. J.A. Astin, C. Reilly, C. Perkins, W.L. Child, and Susan G. Komen Breast Cancer Foundation Breast cancer patients' perspectives on and use of complementary and alternative medicine: a study by the Susan G. Komen Breast Cancer Foundation J Soc Integr Oncol 4 2006 157 169
19. A.R. Jadad, R.A. Moore, and D. Carroll Assessing the quality of reporting of randomised clinical trials: is blinding necessary? Control Clin Trials 17 1996 1 12
20. A.A. Argyriou, E. Chroni, and A. Koutras A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results Support Care Cancer 14 2006 1134 1140
21. A.A. Argyriou, E. Chroni, and A. Koutras Preventing paclitaxel-induced peripheral neuropathy: a phase II trial of vitamin E supplementation J Pain Symptom Manage 32 2006 237 244
22. L.A. Kottschade, J.A. Sloan, and M.A. Mazurczak The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase III clinical trial Support Care Cancer 19 2011 1769 1777
23. A. Pace, A. Savarese, and M. Picardo Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy J Clin Oncol 21 2003 927 931
24. A. Pace, D. Giannarelli, and E. Galiè Vitamin E neuroprotection for cisplatin neuropathy: a randomized, placebo-controlled trial Neurology 74 2010 762 766
25. D. Loven, H. Levavi, and G. Sabach Long-term glutamate supplementation failed to protect against peripheral neurotoxicity of paclitaxel Eur J Cancer Care (Engl) 18 2009 78 83
26. S. Cascinu, L. Cordella, E. Del Ferro, M. Fronzoni, and G. Catalano Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo controlled trial J Clin Oncol 13 1995 26 32
27. S. Cascinu, V. Catalano, and L. Cordella Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: a randomized, double-blind, placebo-controlled trial J Clin Oncol 20 2002 3478 3483
28. V. Catalano, S. Cascinu, and R. Labianca Neuroprotective effect of glutathione (GSH) on oxaliplatin (L-OHP) based chemotherapy in advanced colorectal cancer patients (pts): a randomized double-blind placebo-controlled trial Eur J Cancer 37 2001 S280 S281
29. M. Schmidinger, A.C. Budinsky, and C. Wenzel Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer Wien Klin Wochenschr 112 2000 617 623
30. J.F. Smyth, A. Bowman, and T. Perren Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial Ann Oncol 8 1997 569 573
31. P. Lissoni, S. Barni, and M. Mandala Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status Eur J Cancer 35 1999 1688 1692
32. R. Wadleigh, R. Redman, and M. Graham Vitamin E in the treatment of chemotherapy-induced mucositis Am J Med 92 1992 481 484
33. P.M. Anderson, N.K. Ramsay, and X.O. Shu Effect of low-dose oral glutamine on painful stomatitis during bone marrow transplantation Bone Marrow Transplant 22 1998 339 344
34. P.M. Anderson, G. Schroeder, and K.M. Skubitz Oral glutamine reduces the duration and severity of stomatitis after cytotoxic cancer chemotherapy Cancer 83 1998 1433 1439
35. V.M. Aquino, A.R. Harvey, and J.H. Garvin A double-blind randomized placebo-controlled study of oral glutamine in the prevention of mucositis in children undergoing hematopoietic stem cell transplantation: a pediatric blood and marrow transplant consortium study Bone Marrow Transplant 36 2005 611 616
36. L.C. Cerchietti, A.H. Navigante, and M.A. Lutteral Double-blinded, placebo-controlled trial on intravenous L-alanyl-L-glutamine in the incidence of oral mucositis following chemoradiotherapy in patients with head-and-neck cancer Int J Radiat Oncol Biol Phys 65 2006 1330 1337
37. K. Choi, S.S. Lee, and S.J. Oh The effect of oral glutamine on 5-fluorouracil/leucovorin-induced mucositis/stomatitis assessed by intestinal permeability test Clin Nutr 26 2007 57 62
38. T.M. Coghlin Dickson, R.M. Wong, and J.A. Shizuru Effect of oral glutamine supplementation during bone marrow transplantation JPEN J Parenter Enteral Nutr 24 2000 61 66
39. E.Y. Huang, S.W. Leung, and C.J. Wang Oral glutamine to alleviate radiation-induced oral mucositis: a pilot randomized trial Int J Radiat Oncol Biol Phys 46 2000 535 539
40. S.A. Jebb, R.J. Osborne, and T.S. Maughan 5-Fluorouracil and folinic acid-induced mucositis: no effect of oral glutamine supplementation Br J Cancer 70 1994 732 735
41. S.A. Jebb, R. Marcus, and M. Elia A pilot study of oral glutamine supplementation in patients receiving bone marrow transplants Clin Nutr 14 1995 162 165
42. S.H. Okuno, C.O. Woodhouse, and C.L. Loprinzi Phase III controlled evaluation of glutamine for decreasing stomatitis in patients receiving fluorouracil (5-FU)-based chemotherapy Am J Clin Oncol 22 1999 258 261
43. D.E. Peterson, J.B. Jones, and R.G. Petit Randomized, placebo-controlled study of Saforis for prevention and treatment of oral mucositis in breast cancer patients receiving anthracycline-based chemotherapy Cancer 109 2006 322 331
44. R. Pytlik, P. Benes, and M. Patorkova Standardized parenteral alanyl-glutamine dipeptide supplementation is not beneficial in autologous transplant patients: a randomized, double-blind, placebo controlled study Bone Marrow Transplant 30 2002 953 961
45. P.R. Schloerb, and B.S. Skikne Oral and parenteral glutamine in bone marrow transplantation: a randomized, double-blind study JPEN J Parenter Enteral Nutr 23 1999 117 122
46. H.C. van Zaanen, H. van der Lelie, J.G. Timmer, P. Fürst, and H.P. Sauerwein Parenteral glutamine dipeptide supplementation does not ameliorate chemotherapy-induced toxicity Cancer 74 1994 2879 2884
47. B. Daniele, F. Perrone, and C. Gallo Oral glutamine in the prevention of fluorouracil induced intestinal toxicity: a double blind, placebo controlled, randomised study Gut 48 2001 28 33
48. G. Cerea, M. Vaghi, and A. Ardizzoia Biomodulation of cancer chemotherapy for metastatic colorectal cancer: a randomized study of weekly low-dose irinotecan alone versus irinotecan plus the oncostatic pineal hormone melatonin in metastatic colorectal cancer patients progressing on 5-fluorouracil- containing combinations Anticancer Res 23 2003 1951 1954
49. P. Delia, G. Sansotta, and V. Donato Use of probiotics for prevention of radiation-induced diarrhea World J Gastroenterol 13 2007 912 915
50. P. Osterlund, T. Ruotsalainen, and R. Korpela Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study Br J Cancer 97 2007 1028 1034
51. U.S. Food and Drug Administration. Dietary supplements. Available from http://www.fda.gov/Food/DietarySupplements/ GuidanceComplianceRegulatoryInformation/RegulationsLaws/default.htm. Accessed August 20, 2012.
52. E. Bruera, F. Strasser, and J.L. Palmer Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a double-blind, placebo-controlled study J Clin Oncol 21 2003 129 134
53. J.A. Read, P.J. Beale, and D.H. Volker Nutrition intervention using an eicosapentaenoic acid (EPA)-containing supplement in patients with advanced colorectal cancer. Effects on nutritional and inflammatory status: a phase II trial Support Care Cancer 15 2007 301 307
54. A. Sparreboom, M.C. Cox, M.R. Acharya, and W.D. Figg Herbal remedies in the United States: potential adverse interactions with anticancer agents J Clin Oncol 22 2004 2489 2503
55. S.L. Charland, D.L. Bartlett, and M.H. Torosian A significant methotrexate-glutamine pharmacokinetic interaction Nutrition 11 1995 154 158
56. H. Chamras, S.H. Barsky, and A. Ardashian Novel interactions of vitamin E and estrogen in breast cancer Nutr Cancer 52 2005 43 48
57. J.F. Marín Pozo, J.A. García, A.C. Muriel, and I.C. Porras Hazards of concomitant administration of methotrexate and glutamine Am J Health Syst Pharm 67 2010 601 602
58. I.T. Rubio, Y. Cao, L.F. Hutchins, K.C. Westbrook, and V.S. Klimberg Effect of glutamine on methotrexate efficacy and toxicity Ann Surg 227 1998 772 780
59. M.L. Blackhall, R.G. Fassett, J.E. Sharman, D.P. Geraghty, and J.S. Coombes Effects of antioxidant supplementation on blood cyclosporin A and glomerular filtration rate in renal transplant recipients Nephrol Dial Transplant 20 2005 1970 1975
60. K.D. Lake, K.D. Aaronson, L.E. Gorman, F.D. Pagani, and T.M. Koelling Effect of oral vitamin E and C therapy on calcineurin inhibitor levels in heart transplant recipients J Heart Lung Transplant 24 2005 990 994
61. E.A. Peralta, M.L. Viegas, S. Louis, D.L. Engle, and G.L. Dunnington Effect of vitamin E on tamoxifen-treated breast cancer cells Surgery 140 2006 607 614
62. E.A. Peralta, A.T. Brewer, S. Louis, and G.L. Dunnington Vitamin E increases biomarkers of estrogen stimulation when taken with tamoxifen J Surg Res 153 2009 143 147
63. I. Bairati, F. Meyer, and E. Jobin Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients Int J Cancer 119 2006 2221 2224
64. I. Bairati, F. Meyer, and M. Gélinas Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients J Clin Oncol 23 2005 5805 5813
65. K.N. Prasad, W.C. Cole, B. Kumar, and K. Che Prasad Pros and cons of antioxidant use during radiation therapy Cancer Treat Rev 28 2002 79 91
66. W.S. Wang, J.K. Lin, and T.C. Lin Oral glutamine is effective for preventing oxaliplatin-induced neuropathy in colorectal cancer patients Oncologist 12 2007 312 319
67. M. Frenkel, L. Cohen, and N. Peterson Integrative medicine consultation service in a comprehensive cancer center: findings and outcomes Integr Cancer Ther 9 2010 276 283