Nutrition intervention using an eicosapentaenoic acid (EPA)-containing supplement in patients with advanced colorectal cancer. Effects on nutritional and inflammatory status: A phase II trial

Supportive Care in Cancer

Volumn 15, Issue 3, 2007, Pages 301-307

  Read, Jane A ^a   Beale, Philip J ^a,b   Volker, Dianne H ^b   Smith, Narelle ^c   Childs, Annabel ^a   Clarke, Stephen J ^a,b  

^a Department of Microbiology and Infectious Diseases   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

Chemotherapy; Colorectal cancer; CRP; EPA; Nutritional status; Toxicity

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; FLUOROURACIL; FOLINIC ACID; ICOSAPENTAENOIC ACID; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; IRINOTECAN; PHOSPHOLIPID; PROSURE; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; ANOREXIA; ARTICLE; BODY COMPOSITION; CALORIC INTAKE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER PATIENT; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; COLORECTAL CANCER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIARRHEA; DIET THERAPY; DIETARY INTAKE; DRUG HYPERSENSITIVITY; DRUG WITHDRAWAL; FEMALE; HUMAN; INFLAMMATION; LEAN BODY WEIGHT; LEUKOPENIA; MALE; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NAUSEA AND VOMITING; NEUTROPENIA; NUTRITIONAL STATUS; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN INTAKE; QUALITY OF LIFE; STOMACH DISTENSION;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AUSTRALIA; BIOLOGICAL MARKERS; BODY COMPOSITION; CAMPTOTHECIN; COLORECTAL NEOPLASMS; CYTOKINES; DIETARY PROTEINS; DIETARY SUPPLEMENTS; EICOSAPENTAENOIC ACID; ENERGY INTAKE; FEMALE; FLUOROURACIL; HUMANS; INFLAMMATION; LEUCOVORIN; MALE; MALNUTRITION; MIDDLE AGED; NUTRITIONAL STATUS; NUTRITIONAL SUPPORT; PHOSPHOLIPIDS; QUALITY OF LIFE; TREATMENT OUTCOME; VITAMIN B COMPLEX;

EID: 33847122540     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-006-0153-3     Document Type: Article

References (29)

1. Nozoe T, Matsumata T, Kitamura M, Sugimachi K (1998) Significance of preoperative elevation of serum C-reactive protein as an indicator for prognosis in colorectal cancer. Am J Surg 176:335-338
2. Crozier JE, McKee RF, McArdle CS, Angerson WJ, Anderson JH, Horgan PG, McMillan DC (2006) The presence of a systemic inflammatory response predicts poorer survival in patients receiving adjuvant 5-FU chemotherapy following potentially curative resection for colorectal cancer. Br J Cancer 94(12):1833-1836
3. Nixon DW, Kutner M, Heymsfield S, Foltz AT, Carty C, Seitz S, Casper K, Evans WK, Jeejeebhoy KN, Daly JM et al (1988) Resting energy expenditure in lung and colon cancer. Metabolism 37:1059-1064
4. Dempsey DT, Knox LS, Mullen JL, Miller C, Feurer ID, Buzby GP (1986) Energy expenditure in malnourished patients with colorectal cancer. Arch Surg 121:789-795
5. Ravasco P, Monteiro-Grillo I, Vidal PM, Camilo ME (2005) Dietary counseling improves patient outcomes: a prospective, randomized, controlled trial in colorectal cancer patients undergoing radiotherapy. J Clin Oncol 23:1431-1438
6. Elia M, Van Bokhorst-de van der Schueren MA, Garvey J, Goedhart A, Lundholm K, Nitenberg G, Stratton RJ (2006) Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: a systematic review. Int J Oncol 28:5-23
7. Evans WK, Nixon DW, Daly JM, Ellenberg SS, Gardner L, Wolfe E, Shepherd FA, Feld R, Gralla R, Fine S et al (1987) A randomized study of oral nutritional support versus ad lib nutritional intake during chemotherapy for advanced colorectal and non-small-cell lung cancer. J Clin Oncol 5:113-124
8. Barber MD, Ross JA, Voss AC, Tisdale MJ, Fearon KC (1999) The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer. Br J Cancer 81:80-86
9. Bauer JD, Capra S (2005) Nutrition intervention improves outcomes in patients with cancer cachexia receiving chemotherapy - a pilot study. Support Care Cancer 13:270-274
10. Fearon KC, Von Meyenfeldt MF, Moses AG, Van Geenen R, Roy A, Gouma DJ, Giacosa A, Van Gossum A, Bauer J, Barber MD et al (2003) Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut 52:1479-1486
11. Moses AW, Slater C, Preston T, Barber MD, Fearon KC (2004) Reduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with n-3 fatty acids. Br J Cancer 90:996-1002
12. Barber MD, Ross JA, Preston T, Shenkin A, Fearon KC (1999) Fish oil-enriched nutritional supplement attenuates progression of the acute-phase response in weight-losing patients with advanced pancreatic cancer. J Nutr 129:1120-1125
13. Chung YC, Chang YF (2003) Serum interleukin-6 levels reflect the disease status of colorectal cancer. J Surg Oncol 83:222-226
14. Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der Meer JW, Cannon JG, Rogers TS, Klempner MS, Weber PC et al (1989) The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 320:265-271
15. Meydani SN (1992) Modulation of cytokine production by dietary polyunsaturated fatty acids. Proc Soc Exp Biol Med 200:189-193
16. Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL (1991) Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women. J Nutr 121:547-555
17. Hardman WE (2002) Omega-3 fatty acids to augment cancer therapy. J Nutr 132:3508S-3512S
18. Hardman WE, Moyer MP, Cameron IL (1999) Fish oil supplementation enhanced CPT-11 (irinotecan) efficacy against MCF7 breast carcinoma xenografts and ameliorated intestinal sideeffects. Br J Cancer 81:440-448
19. Lukaski HC, Bolonchuk WW, Hall CB, Siders WA (1986) Validation of tetrapolar bioelectrical impedance method to assess human body composition. J Appl Physiol 60:1327-1332
20. Nowak A, Stockler MR, Heritier S, Goldstein D, Turner J, Jefford M, Glasgow A, Abdi E, Beale PJ, Carter C (2006) (For the ZEST trial group). The most troublesome aspects of quality of life for people with advanced cancer in a supportive care trial. Proc Amer Soc Clin Oncol 24:18S
21. Lepage G, Roy CC (1986) Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 27:114-120
22. Garg M, Blake R (1997) Cholesterol dynamics in rats fed diets containing either canola or sunflower oil. Nutr Res 17:485-492
23. R&D Systems (2006) Multiplex kits for the luminex platform. Minneapolis http://www.rndsystems.com/ product_detail_objectname_multiplexkitsluminex.aspx
24. Gibney MJ, Hunter B (1993) The effects of short- and long-term supplementation with fish oil on the incorporation of n-3 polyunsaturated fatty acids into cells of the immune system in healthy volunteers. Eur J Clin Nutr 47:255-259
25. Bauer J, Capra S, BattistuttaD,Davidson W, Ash S (2005) Compliance with nutrition prescription improves outcomes in patients with unresectable pancreatic cancer. Clin Nutr 24:998-1004
26. Martin F, Santolaria F, Batista N, Milena A, Gonzalez-Reimers E, Brito MJ, Oramas J (1999) Cytokine levels (IL-6 and IFN-gamma), acute phase response and nutritional status as prognostic factors in lung cancer. Cytokine 11:80-86
27. Ferrucci L, Cherubini A, Bandinelli S, Bartali B, Corsi A, Lauretani F, Martin A, Andres-Lacueva C, Senin U, Guralnik JM (2006) Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab 91:439-446
28. Isenring E, Bauer J, Capra S (2003) The scored patient-generated subjective global assessment (PG-SGA) and its association with quality of life in ambulatory patients receiving radiotherapy. Eur J Clin Nutr 57:305-309
29. Andreyev HJ, Norman AR, Oates J, Cunningham D (1998) Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies? Eur J Cancer 34:503-509