Mutated CaV2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice

Molecular Pain

Volumn 9, Issue 1, 2013, Pages

  Gnanasekaran, Aswini ^a   Bele, Tanja ^c   Hullugundi, Swathi ^a   Simonetti, Manuela ^a,d   Ferrari, Michael D ^b   van den Maagdenberg, Arn M J M ^b   Nistri, Andrea ^a   Fabbretti, Elsa ^a,c  

^a SISSA   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF NOVA GORICA   (Slovenia)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

ATP; DRG; Migraine; Pain; Purinergic signaling; Trigeminal ganglion

Indexed keywords

CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CHANNEL; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; OMEGA AGATOXIN IVA; PURINERGIC P2X3 RECEPTOR; UNCLASSIFIED DRUG; VOLTAGE GATED CAV2.1 CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; CASK KINASES; GUANYLATE KINASE; VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; GAIN OF FUNCTION MUTATION; HEMIPLEGIC MIGRAINE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRIGEMINUS GANGLION; ANIMAL; CYTOLOGY; GENETICS; METABOLISM; MUTATION; SENSORY NERVE CELL; TRANSGENIC MOUSE;

ANIMALS; CALCIUM CHANNELS, N-TYPE; GUANYLATE KINASES; MICE; MICE, TRANSGENIC; MUTATION; RECEPTORS, PURINERGIC P2X3; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; TRIGEMINAL GANGLION;

MLCS; MLOWN;

EID: 84888630482     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-9-62     Document Type: Article

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