B7-H4 expression is elevated in human U251 glioma stem-like cells and is inducible in monocytes cultured with U251 stem-like cell conditioned medium

Chinese Journal of Cancer

Volumn 32, Issue 12, 2013, Pages 653-660

  Mo, Lian Jie ^a   Ye, Hong Xing ^b   Mao, Ying ^b   Yao, Yu ^b   Zhang, Jian Min ^a  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

B7 H4; Brain tumor stem cells; Monocytes; U251 cells

Indexed keywords

CD133 ANTIGEN; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; TRANSCRIPTION FACTOR SOX2; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1;

ARTICLE; CELL ADHESION; CELL CULTURE; CELLULAR IMMUNITY; CONTROLLED STUDY; FLOW CYTOMETRY; GLIOMA; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; MONOCYTE; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT;

ANTIGENS, CD; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CULTURE MEDIA, SERUM-FREE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOMA; GLYCOPROTEINS; HUMANS; MONOCYTES; NEOPLASTIC STEM CELLS; NESTIN; PEPTIDES; SOXB1 TRANSCRIPTION FACTORS; V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1;

EID: 84888596818     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.012.10228     Document Type: Article

References (40)

1. Davis FG, Frees S, Grutsch J, et al. Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis base on surveillance, epidemiology, end results (SEER) data 1973-1991. J Neurosurg, 1998, 88:1-10.
2. Kelly KA, Kirkwood JM, Kapp DS. Glioblastoma multiforme: pathology, natural history and treatment. Cancer Treat, 1984,11:1-26.
3. Surawicz TS, Davis F, Frells S, et al. Brain tumor survival: results from the National Cancer Data Base. J Neurooncol, 1998,40:151-160.
4. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med, 2008,359:492-507.
5. Sakariassen PO, Immervoll H, Chekenya M. Cancer stem cells as mediators of treatment resistance in brain tumors: status and controversies. Neoplasm, 2007,9:882-892.
6. Perez Castillo A, Aguilar-Morante D, Morales-Garcia, JA, et al. Cancer stem cell and brain tumors. Clin Transl Oncol, 2008,10:262-267.
7. Piccirillo SG, Combi R, Cajola L, et al. Distinct pools of cancer stem-like cells coexist within human glioblastoma and display different tumorigenicity and independent genomic evolution. Oncogene, 2009,28:1807-1811.
8. + cells isolated from human astrocytomas and associated with transformation of human astrocytes. Biochim Biophys Acta, 2007,1769:437-442.
9. Oka N, Soeda A, Noda S, et al. Brain tumor stem cell from an adenoid glioblastoma multiforme. Neurol Med Chir, 2009,49:146-151.
10. + cancer stem cells in glioblastoma. Mol Cancer, 2006,5:67.
11. Bleau AM, Howard BM, Taylor LA, et al, New strategy for the analysis of phenotypic marker antigens in brain tumorderived neurospheres in mice and humans. Neurosurg Focus, 2008,24:E28.
12. Chinnayan P, Wang M, Rojiani AM, et al. The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the radiation therapy oncology group. Radiat Oncol, 2008,3:32.
13. Fan X, Salford LG, Widegren B. Glioma stem cell: evidence and limitation. Semin. Cancer Biol, 2007,17:214-218.
14. Reya T, Morrison SJ, Clarke MF, et al. Stem cells, cancer, and cancer stem cells. Nature, 2001,414:105-111.
15. Molina JR, Hayashi Y, Stephens C, et al. Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia, 2010,12:453-463.
16. Yao XH, Ping YF, Chen JH, et al. Glioblastoma stem cells produce vascular endothelial growth factor by activation of a G-protein coupled formylpeptide receptor FPR. J Pathol, 2008,215:369-376.
17. Bao SD, Wu QL, Sathornsumetee S, et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res, 2006,66:7843-7848.
18. Bao SD, Wu QL, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature, 2006,444:756-760.
19. Porta CL, Alessandri G, Marras C, et al. Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia, 2006,54:850-860.
20. Sica GL, Choi IH, Zhu G, et al. B7-H4, a molecule of the B7 family negatively regulates T cell immunity. Immunity, 2003,18:849-861.
21. Prasad DV, Richards S, Mai XM, et al. B7S1, a novel B7 family member that negatively regulates T cell activation. Immunity, 2003,18:863-873.
22. Zang X, Loke P, Kim J, et al. B7x: a widely expressed B7 family member that inhibits T cell activation. Proc Natl Acad Sci USA, 2003,100:10388-10392.
23. Ichikawa M, Chen L. Role of B7-H1 and B7-H4 molecules in down-regulating effector phase of T-cell immunity: novel cancer escaping mechanisms. Front Biosci, 2005,10:2856-2860.
24. Sun Y, Wang Y, Zhao J, et al. B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung Cancer, 2006,53:143-151.
25. Salceda S, Tang T, Kmet M, et al. The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation. Exp Cell Res, 2005,306:128-141.
26. Tringler B, Zhuo S, Pilkington G, et al. B7-h4 is highly expressed in ductal and lobular breast cancer. Clin Cancer Res, 2005,11:1842-1848.
27. Crispen PL, Boorjian SA, Lohse CM, et al. Predicting disease progression after nephrectomy for localized renal cell carcinoma: the utility of prognostic models and molecular biomarkers. Cancer, 2008,113:450-460.
28. Ficarra V, Galfano A, Novara G, et al. Risk stratification and prognostication of renal cell carcinoma. World J Urol, 2008,26:115-125.
29. Krambeck AE, Thompson RH, Dong H, et al. B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. Proc Natl Acad Sci USA, 2006,103:10391-10396.
30. Salceda S, Tang T, Kmet M, et al. The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation. Exp Cell Res, 2005,306:128-141.
31. Yao Y, Wang X, Jin K, et al. B7-H4 is preferentially expressed in non-dividing brain tumor cells and in a subset of brain tumor stem-like cells. J Neurooncol, 2008,89:121-129.
32. Miyatake T, Tringler B, Liu W, et al. B7-H4 (DD-O110) i s overexpres sed in high r i s k uter ine endomet r ioi d adenocarcinomas and inversely correlated with tumor T-cell infiltration. Gynecol Oncol, 2007,106:119-127.
33. Lu B, Chen L, Liu L, et al. T-cell-mediated tumor immune surveillance and expression of B7 co-inhibitory molecules in cancers of the upper gastrointestinal tract. Immunol Res, 2011,50:269-275.
34. Flies DB, Chen L. The new B7s: playing a pivotal role in tumor immunity. J Immunother, 2007,30:251-260.
35. Graham JM. Isolation of peripheral blood mononuclear cells from macaques on a density barrier. ScientificWorldJournal, 2002,2:1654-1656.
36. Pollard SM, Yoshikawa K, Clarke ID, et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell, 2009,4:568-580.
37. Choi IH, Zhu G, Sica GL, et al. Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family. J Immunol, 2003,171:4650-4654.
38. Kryczek I, Zou L, Rodriguez P, et al. B7-H4 expression identi-es a novel suppressive macrophage population in human ovarian carcinoma. J Exp Med, 2006,203:871-881.
39. Chen C, Qu QX, Shen Y, et al. Induced expression of B7-H4 on the surface of lung cancer cell by the tumor-associated macrophages: a potential mechanism of immune escape. Cancer Lett, 2012,317:99-105.
40. Wu A, Wei J, Kong LY, et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol, 2010,12:1113-1125.