Grape pomace enzymatic extract restores vascular dysfunction evoked by endothelin-1 and DETCA via NADPH oxidase downregulation and SOD activation

Journal of Functional Foods

Volumn 5, Issue 4, 2013, Pages 1673-1683

  Perez Ternero, Cristina ^a   Rodriguez Rodriguez, Rosalia ^a   Parrado, Juan ^a   Alvarez de Sotomayor, Maria ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Catechin; Epicatechin; Grape pomace; NADPH oxidase; Oxidative stress; Superoxide dismutase

Indexed keywords

VITACEAE;

EID: 84888440506     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2013.07.012     Document Type: Article

References (41)

1. Agouni A., Lagrue-Lak-Hal A.H., Mostefai H.A., Tesse A., Mulder P., Rouet P., et al. Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa). PLoS ONE 2009, 4:18-25.
2. Alvarez E., Rodino-Janeiro B.K., Jerez M., Ucieda-Somoza R., Nunez M.J., Gonzalez-Juanatey J.R. Procyanidins from grape pomace are suitable inhibitors of human endothelial NADPH oxidase. Journal of Cellular Biochemistry 2012, 113:1386-1396.
3. Anselm E., Chataigneau M., Ndiaye M., Chataigneau T., Schini-Kerth V.B. Grape juice causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of eNOS. Cardiovascular Research 2007, 73:404-413.
4. Brossette T., Hundsdorfer C., Kroncke K.D., Sies H., Stahl W. Direct evidence that (-)-epicatechin increases nitric oxide levels in human endothelial cells. European Journal of Nutrition 2011, 50:595-599.
5. Dai D.Z., Dai Y. Role of endothelin receptor A and NADPH oxidase in vascular abnormalities. Journal of Vascular Health and Risk Management 2010, 6:787-794.
6. de Lorgeril M., Salen P., Paillard F., Laporte F., Boucher F., de Leiris J. Mediterranean diet and the French paradox: Two distinct biogeographic concepts for one consolidated scientific theory on the role of nutrition in coronary heart disease. Cardiovascular Research 2002, 54:503-515.
7. de Sotomayor M.A., Mingorance C., Rodriguez-Rodriguez R., Marhuenda E., Herrera M.D. l-Carnitine and its propionate: Improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms. Free Radical Research 2007, 41:884-891.
8. Di Castelnuovo A., Rotondo S., Iacoviello L., Donati M.B., De Gaetano G. Meta-analysis of wine and beer consumption in relation to vascular risk. Circulation 2002, 105:2836-2844.
9. Duarte J., Andriambeloson E., Diebolt M., Andriantsitohaina R. Wine polyphenols stimulate superoxide anion production to promote calcium signaling and endothelial-dependent vasodilatation. Physiological Research 2004, 53:595-602.
10. Edirisinghe I., Burton-Freeman B., Tissa Kappagoda C. Mechanism of the endothelium-dependent relaxation evoked by a grape seed extract. Clinical Sciences 2008, 114:331-337.
11. Fukai T., Folz R.J., Landmesser U., Harrison D.G. Extracellular superoxide dismutase and cardiovascular disease. Cardiovascular Research 2002, 55:239-249.
12. Gollücke A.P., Ribeiro D.A. Use of grape polyphenols for promoting human health: A review of patents. Recent Patents on Food, Nutrition & Agriculture 2012, 4:26-30.
13. Grønbaek M., Becker U., Johansen D., Gottschau A., Schnohr P., Hein H.O., et al. Type of alcohol consumed and mortality from all causes, coronary heart disease, and cancer. Annals of Internal Medicine 2000, 133:411-419.
14. Hertog M.G., Kromhout D., Aravanis C., Blackburn H., Buzina R., Fidanza F., et al. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Archives of Internal Medicine 1995, 155:381-386.
15. Lassegue B., Sorescu D., Szocs K., Yin Q., Akers M., Zhang Y., et al. Novel gp91(phox) homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circulation Research 2001, 88:888-894.
16. Loomis E.D., Sullivan J.C., Osmond D.A., Pollock D.M., Pollock J.S. Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. Journal of Pharmacology and Experimental Therapeutics 2005, 315:1058-1064.
17. Lopez de Lerma N., Peinado J., Peinado R.A. In vitro and in vivo antioxidant activity of musts and skin extracts from off-vine dried Vitis vinifera cv. "Tempranillo" grapes. Journal of Functional Foods 2013, 5:914-922.
18. Lopez-Sepulveda R., Gomez-Guzman M., Zarzuelo M.J., Romero M., Sanchez M., Quintela A.M., et al. Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: Role of NADPH oxidase. Clinical Sciences 2011, 120:321-333.
19. Lorrain B., Ky I., Pechamat L., Teissedre P.L. Evolution of analysis of polyhenols from grapes, wines, and extracts. Molecules 2013, 18:1076-1100.
20. MacMillan-Crow L.A., Cruthirds D.L. Invited review: Manganese superoxide dismutase in disease. Free Radical Research 2001, 34:325-336.
21. Madeira S.V., Auger C., Anselm E., Chataigneau M., Chataigneau T., Soares de Moura R. ENOS activation induced by a polyphenol-rich grape skin extract in porcine coronary arteries. Journal of Vascular Research 2009, 46:406-416.
22. Martin K.R., Appel C.L. Polyphenols as dietary supplements: A double-edged sword. Nutrition and Dietary Supplements 2010, 2:1-12.
23. Menendez C., Jimenez R., Moreno L., Galindo P., Cogolludo A., Duarte J., et al. Lack of synergistic interaction between quercetin and catechin in systemic and pulmonary vascular smooth muscle. British Journal of Nutrition 2011, 105:1287-1293.
24. Mukamal K.J., Maclure M., Muller J.E., Sherwood J.B., Mittleman M.A. Tea consumption and mortality after acute myocardial infarction. Circulation 2002, 105:2476-2481.
25. Nijveldt R.J., van Nood E., van Hoorn D.E., Boelens P.G., van Norren K., van Leeuwen P.A. Flavonoids: A review of probable mechanisms of action and potential applications. American Journal of Clinical Nutrition 2001, 74:418-425.
26. Noguer M.A., Cerezo A.B., Donoso Navarro E., Garcia-Parrilla M.C. Intake of alcohol-free red wine modulates antioxidant enzyme activities in a human intervention study. Pharmacological Research 2012, 65:609-614.
27. Pandey K.B., Rizvi S.I. Plant polyphenols as dietary antioxidants in human health and disease. Oxidative Medicine and Cellular Longevity 2009, 2:270-278.
28. Pérez-Guerrero C., Márquez-Martín A., Herrera M.D., Marhuenda E., de Sotomayor M.A. Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin. Pharmacology 2005, 74:209-215.
29. Ramirez-Sanchez I., Maya L., Ceballos G., Villarreal F. (-)-Epicatechin induces calcium and translocation independent eNOS activation in arterial endothelial cells. American Journal of Physiology-Cell Physiology 2011, 300:C880-C887.
30. Redondo A., Estrella N., Lorenzo A.G., Cruzado M., Castro C. Quercetin and catechin synergistically inhibit angiotensin II-induced redox-dependent signalling pathways in vascular smooth muscle cells from hypertensive rats. Free Radical Research 2012, 46:619-627.
31. Rodriguez-Rodriguez R., Herrera M.D., Perona J.S., Ruiz-Gutierrez V. Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in 'orujo' olive oil, on rat aorta. British Journal of Nutrition 2004, 92:635-642.
32. Rodriguez-Rodriguez R., Justo M.L., Claro C.M., Vila E., Parrado J., Herrera M.D., de Sotomayor M.A. Endothelium-dependent vasodilator and antioxidant properties of a novel enzymatic extract of grape pomace from wine industrial waste. Food Chemistry 2012, 135:1044-1051.
33. Rodriguez-Rodriguez R., Munoz-Berbel X., Demming S., Buttgenbach S., Herrera M.D., Llobera A. Cell-based microfluidic device for screening anti-proliferative activity of drugs in vascular smooth muscle cells. Biomedical Microdevices 2012, 14:1129-1140.
34. Sanae F., Miyaichi Y., Kizu H., Hayashi H. Effects of catechins on vascular tone in rat thoracic aorta with endothelium. Life Sciences 2002, 71:2553-2562.
35. Sarr M., Chataigneau M., Martins S., Schott C., El Bedoui J., Oak M.H., et al. Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: Role of NADPH oxidase. Cardiovascular Research 2006, 71:794-802.
36. Schini-Kerth V.B., Auger C., Kim J.H., Etienne-Selloum N., Chataigneau T. Nutritional improvement of the endothelial control of vascular tone by polyphenols: Role of NO and EDHF. Pflugers Archiv: European Journal of Physiology 2010, 459:853-862.
37. Sofi F., Cesari F., Abbate R., Gensini G.F., Casini A. Adherence to Mediterranean diet and health status: Meta-analysis. BMJ 2008, 337:a1344.
38. Stoclet J.C., Chataigneau T., Ndiaye M., Oak M.H., El Bedoui J., Chataigneau M., et al. Vascular protection by dietary polyphenols. European Journal of Pharmacology 2004, 500:299-313.
39. Vislocky L.M., Fernandez M.L. Biomedical effects of grape products. Nutrition Reviews 2010, 68:656-670.
40. - mediated endothelium-dependent relaxations. American Journal of Physiology 1999, 276(3 Pt 2):H1043-H1048.
41. Xia E.Q., Deng G.F., Guo Y.J., Li H.B. Biological activities of polyphenols from grapes. International Journal of Molecular Sciences 2010, 11:622-646.