A role for benzo[a]pyrene and Slug in invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis: A potential molecular link between smoking and radiographic progression

Joint Bone Spine

Volumn 80, Issue 6, 2013, Pages 621-625

  Lee, Jaejoon ^a   Jeong, Hyemin ^a   Park, Eun Jung ^a   Hwang, Ji Won ^a   Bae, Eun Kyung ^b   Ahn, Joong Kyong ^c   Ahn, Kwang Sung ^d   Koh, Eun Mi ^a   Cha, Hoon Suk ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Samsung Medical Center   (South Korea)

^c School of Medicine   (South Korea)

^d Seoul National University Hospital   (South Korea)

Author keywords

Joint erosions; Rheumatoid Arthritis; Risk factors; Synoviocytes; Tobacco

Indexed keywords

BENZO[A]PYRENE; COMPLEMENTARY DNA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR SLUG; SNAIL FAMILY TRANSCRIPTION FACTORS; TOXIC SUBSTANCE; TRANSCRIPTION FACTOR;

ARTICLE; CELL INVASION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FIBROBLAST LIKE SYNOVIOCYTE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; RNA INTERFERENCE; SMOKING; SYNOVIOCYTE; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CELL CULTURE; GENETICS; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SYNOVIUM;

ARTHRITIS, RHEUMATOID; BENZO(A)PYRENE; CELLS, CULTURED; HUMANS; NOXAE; SIGNAL TRANSDUCTION; SMOKING; SYNOVIAL MEMBRANE; TRANSCRIPTION FACTORS;

EID: 84888435484     PISSN: 1297319X     EISSN: 17787254     Source Type: Journal    
DOI: 10.1016/j.jbspin.2013.02.009     Document Type: Article

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