Analysis of gene expression in canine idiopathic pulmonary fibrosis

Veterinary Journal

Volumn 198, Issue 2, 2013, Pages 479-486

  Krafft, E ^a   Laurila, H P ^b   Peters, I R ^c   Bureau, F ^a   Peeters, D ^a   Day, M J ^d   Rajamaki M M ^b   Clercx, C ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Canine; Chemokine ligand 2; Gene expression; Idiopathic pulmonary fibrosis; Microarray analysis

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; BREEDING; CCL2 GENE; CELL INTERACTION; CELL MOTION; CELL PROLIFERATION; CONTROLLED STUDY; EXPERIMENTAL DOG; FEMALE; FIBROBLAST ACTIVATION PROTEIN GENE; FIBROSING ALVEOLITIS; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; INTERLEUKIN 8 GENE; INTRACELLULAR SIGNALING; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLUNC GENE; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CANIS FAMILIARIS;

CANINE; CHEMOKINE LIGAND 2; GENE EXPRESSION; IDIOPATHIC PULMONARY FIBROSIS; MICROARRAY ANALYSIS;

ANIMALS; BIOLOGICAL MARKERS; CHEMOKINE CCL2; DOG DISEASES; DOGS; FEMALE; GENE EXPRESSION REGULATION; IDIOPATHIC PULMONARY FIBROSIS; LUNG; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TRANSCRIPTOME;

EID: 84888428805     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2013.08.018     Document Type: Article

References (52)

1. Acharya P.S., Zukas A., Chandan V., Katzenstein A.L., Pure E. Fibroblast activation protein: A serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis. Human Pathology 2006, 37:352-360.
2. Antoniades H.N., Neville-Golden J., Galanopoulos T., Kradin R.L., Valente A.J., Graves D.T. Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis. Proceedings of the National Academy of Sciences of the USA 1992, 89:5371-5375.
3. Augsten M., Hagglof C., Olsson E., Stolz C., Tsagozis P., Levchenko T., Frederick M.J., Borg A., Micke P., Egevad, et al. CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth. Proceedings of the National Academy of Sciences of the USA 2009, 106:3414-3419.
4. Bartlett J.A., Gakhar L., Penterman J., Singh P.K., Mallampalli R.K., Porter E., McCray P.B. PLUNC: A multifunctional surfactant of the airways. Biochemical Society Transactions 2011, 39:1012-1016.
5. Buhling F., Wille A., Rocken C., Wiesner O., Baier A., Meinecke I., Welte T., Pap T. Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis. Respiratory Research 2005, 6:37.
6. Carre P.C., Mortenson R.L., King T.E., Noble P.W., Sable C.L., Riches D.W. Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis. Journal of Clinical Investigation 1991, 88:1802-1810.
7. Corcoran B.M., Cobb M., Martin M.W., Dukes-McEwan J., French A., Fuentes V.L., Boswood A., Rhind S. Chronic pulmonary disease in West Highland white terriers. Veterinary Record 1999, 144:611-616.
8. Coward W.R., Saini G., Jenkins G. The pathogenesis of idiopathic pulmonary fibrosis. Therapeutic Advances in Respiratory Disease 2010, 4:367-388.
9. Datta A., Scotton C.J., Chambers R.C. Novel therapeutic approaches for pulmonary fibrosis. British Journal of Pharmacology 2011, 163:141-172.
10. Gakhar L., Bartlett J.A., Penterman J., Mizrachi D., Singh P.K., Mallampalli R.K., Ramaswamy S., McCray P.B. PLUNC is a novel airway surfactant protein with anti-biofilm activity. PLoS ONE 2010, 5:e9098.
11. Gharaee-Kermani M., Denholm E.M., Phan S.H. Costimulation of fibroblast collagen and transforming growth factor β1 gene expression by monocyte chemoattractant protein-1 via specific receptors. Journal of Biological Chemistry 1996, 271:17779-17784.
12. Heikkila H.P., Lappalainen A.K., Day M.J., Clercx C., Rajamaki M.M. Clinical, bronchoscopic, histopathologic, diagnostic imaging, and arterial oxygenation findings in West Highland White Terriers with idiopathic pulmonary fibrosis. Journal of Veterinary Internal Medicine 2011, 25:433-439.
13. Johnson V.S., Corcoran B.M., Wotton P.R., Schwarz T., Sullivan M. Thoracic high-resolution computed tomographic findings in dogs with canine idiopathic pulmonary fibrosis. Journal of Small Animal Practice 2005, 46:381-388.
14. Kaminski N. Microarray analysis of idiopathic pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology 2003, 29:S32-S36.
15. Kaminski N., Allard J.D., Pittet J.F., Zuo F., Griffiths M.J., Morris D., Huang X., Sheppard D., Heller R.A. Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis. Proceedings of the National Academy of Sciences of the USA 2000, 97:1778-1783.
16. Kaminski N., Friedman N. Practical approaches to analyzing results of microarray experiments. American Journal of Respiratory Cell and Molecular Biology 2002, 27:125-132.
17. Kaminski N., Rosas I.O. Gene expression profiling as a window into idiopathic pulmonary fibrosis pathogenesis: Can we identify the right target genes?. Proceedings of the American Thoracic Society 2006, 3:339-344.
18. Kelly M.M., Leigh R., Gilpin S.E., Cheng E., Martin G.E., Radford K., Cox G., Gauldie J. Cell-specific gene expression in patients with usual interstitial pneumonia. American Journal of Respiratory and Critical Care Medicine 2006, 174:557-565.
19. Konishi K., Gibson K.F., Lindell K.O., Richards T.J., Zhang Y., Dhir R., Bisceglia M., Gilbert S., Yousem S.A., Song J.W., et al. Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 2009, 180:167-175.
20. Krafft E., Heikkila H.P., Jespers P., Peeters D., Day M.J., Rajamaki M.M., McEntee K., Clercx C. Serum and bronchoalveolar lavage fluid endothelin-1 concentrations as diagnostic biomarkers of canine idiopathic pulmonary fibrosis. Journal of Veterinary Internal Medicine 2011, 25:990-996.
21. Kurth I., Willimann K., Schaerli P., Hunziker T., Clark-Lewis I., Moser B. Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development. Journal of Experimental Medicine 2001, 194:855-861.
22. -δδCT method. Methods 2001, 25:402-408.
23. Maeyama T., Kuwano K., Kawasaki M., Kunitake R., Hagimoto N., Matsuba T., Yoshimi M., Inoshima I., Yoshida K., Hara N. Upregulation of Fas-signalling molecules in lung epithelial cells from patients with idiopathic pulmonary fibrosis. European Respiratory Journal 2001, 17:180-189.
24. Maher T.M. Idiopathic pulmonary fibrosis: Pathobiology of novel approaches to treatment. Clinics in Chest Medicine 2012, 33:69-83.
25. Moodley Y.P., Caterina P., Scaffidi A.K., Misso N.L., Papadimitriou J.M., McAnulty R.J., Laurent G.J., Thompson P.J., Knight D.A. Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis. Journal of Pathology 2004, 202:486-495.
26. Moodley Y.P., Misso N.L., Scaffidi A.K., Fogel-Petrovic M., McAnulty R.J., Laurent G.J., Thompson P.J., Knight D.A. Inverse effects of interleukin-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs. American Journal of Respiratory Cell and Molecular Biology 2003, 29:490-498.
27. Moodley Y.P., Scaffidi A.K., Misso N.L., Keerthisingam C., McAnulty R.J., Laurent G.J., Mutsaers S.E., Thompson P.J., Knight D.A. Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation. American Journal of Pathology 2003, 163:345-354.
28. Niedermeyer J., Garin-Chesa P., Kriz M., Hilberg F., Mueller E., Bamberger U., Rettig W.J., Schnapp A. Expression of the fibroblast activation protein during mouse embryo development. International Journal of Developmental Biology 2001, 45:445-447.
29. Norris A.J., Naydan D.K., Wilson D.W. Interstitial lung disease in West Highland White Terriers. Veterinary Pathology 2005, 42:35-41.
30. Oyama M.A., Chittur S. Genomic expression patterns of cardiac tissues from dogs with dilated cardiomyopathy. American Journal of Veterinary Research 2005, 66:1140-1155.
31. Pardo A., Selman M. Matrix metalloproteases in aberrant fibrotic tissue remodeling. Proceedings of the American Thoracic Society 2006, 3:383-388.
32. Peeters D., Peters I.R., Farnir F., Clercx C., Day M.J. Real-time RT-PCR quantification of mRNA encoding cytokines and chemokines in histologically normal canine nasal, bronchial and pulmonary tissue. Veterinary Immunology and Immunopathology 2005, 104:195-204.
33. Peeters D., Peters I.R., Clercx C., Day M.J. Real-time RT-PCR quantification of mRNA encoding cytokines, CC chemokines and CCR3 in bronchial biopsies from dogs with eosinophilic bronchopneumopathy. Veterinary Immunology and Immunopathology 2006, 110:65-77.
34. Peeters D., Peters I.R., Helps C.R., Gabriel A., Day M.J., Clercx C. Distinct tissue cytokine and chemokine mRNA expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinitis. Veterinary Immunology and Immunopathology 2007, 117:95-105.
35. Peters I.R., Helps C.R., Hall E.J., Day M.J. Real-time RT-PCR: Considerations for efficient and sensitive assay design. Journal of Immunological Methods 2004, 286:203-217.
36. Peters I.R., Peeters D., Helps C.R., Day M.J. Development and application of multiple internal reference (housekeeper) gene assays for accurate normalisation of canine gene expression studies. Veterinary Immunology and Immunopathology 2007, 117:55-66.
37. Prasse A., Müller-Quernheim J. Non-invasive biomarkers in pulmonary fibrosis. Respirology 2009, 14:788-795.
38. Richards T.J., Kaminski N., Baribaud F., Flavin S., Brodmerkel C., Horowitz D., Li K., Choi J., Vuga L.J., Lindell K.O., et al. Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 2012, 185:67-76.
39. Rosas I.O., Richards T.J., Konishi K., Zhang Y., Gibson K., Lokshin A.E., Lindell K.O., Cisneros J., Macdonald S.D., Pardo A., et al. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Medicine 2008, 5:e93.
40. Sekiya T., Miyamasu M., Imanishi M., Yamada H., Nakajima T., Yamaguchi M., Fujisawa T., Pawankar R., Sano Y., Ohta K., et al. Inducible expression of a Th2-type CC chemokine thymus- and activation-regulated chemokine by human bronchial epithelial cells. Journal of Immunology 2000, 165:2205-2213.
41. Selman M., Carrillo G., Estrada A., Mejia M., Becerril C., Cisneros J., Gaxiola M., Perez-Padilla R., Navarro C., Richards T., et al. Accelerated variant of idiopathic pulmonary fibrosis: Clinical behavior and gene expression pattern. PLoS ONE 2007, 2:e482.
42. Selman M., Pardo A., Kaminski N. Idiopathic pulmonary fibrosis: Aberrant recapitulation of developmental programs?. PLoS Medicine 2008, 5:e62.
43. Song J.W., Do K.H., Jang S.J., Colby T.V., Han S., Kim D.S. Blood biomarkers MMP-7 and SP-A: Predictors of outcome in idiopathic pulmonary fibrosis. Chest 2013, 143:1422-1429.
44. Starnes T., Rasila K.K., Robertson M.J., Brahmi Z., Dahl R., Christopherson K., Hromas R. The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: Implications for the downregulation of CXCL14 in malignancy. Experimental Hematology 2006, 34:1101-1105.
45. Sterling T., Danail B. A survey of current software for network analysis in molecular biology. Human Genomics 2010, 4:353-360.
46. Strieter R.M. What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis. Proceedings of the American Thoracic Society 2008, 5:305-310.
47. Studer S.M., Kaminski N. Towards systems biology of human pulmonary fibrosis. Proceedings of the American Thoracic Society 2007, 4:85-91.
48. Syrjä P., Heikkilä H.P., Lilja-Maula L., Krafft E., Clercx C., Day M.J., Rönty M., Myllärniemi M., Rajamäki M.M. The histopathology of idiopathic pulmonary fibrosis in West Highland white terriers shares features of both non-specific interstitial pneumonia and usual interstitial pneumonia in man. Journal of Comparative Pathology 2013, 149:303-313.
49. Vij R., Noth I. Peripheral blood biomarkers in idiopathic pulmonary fibrosis. Translational Research 2012, 159:218-227.
50. Wilson M.S., Wynn T.A. Pulmonary fibrosis: Pathogenesis, etiology and regulation. Mucosal Immunology 2009, 2:103-121.
51. Yamashita C.M., Dolgonos L., Zemans R.L., Young S.K., Robertson J., Briones N., Suzuki T., Campbell M.N., Gauldie J., Radisky D.C., et al. Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. American Journal of Pathology 2011, 179:1733-1745.
52. Zuo F., Kaminski N., Eugui E., Allard J., Yakhini Z., Ben-Dor A., Lollini L., Morris D., Kim Y., DeLustro B., et al. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proceedings of the National Academy of Sciences of the USA 2002, 99:6292-6297.