Multiple sites on Streptococcus gordonii surface protein PadA bind to platelet GPIIbIIIa

Thrombosis and Haemostasis

Volumn 110, Issue 6, 2013, Pages 1278-1287

  Keane, Ciara ^a   Petersen, Helen J ^b   Tilley, Dorothea O ^a   Haworth, Jennifer ^b   Cox, Dermot ^a   Jenkinson, Howard F ^b   Kerrigan, Steve W ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Aggregation; Bacterial surface protein; Dense granule release; Platelet adhesion; Shear adhesion; Spreading

Indexed keywords

BACTERIAL PROTEIN; FIBRINOGEN RECEPTOR; PLATELET ADHERENCE PROTEIN A; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL SPREADING; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PURIFICATION; PROTEOMICS; SECRETORY GRANULE; SITE DIRECTED MUTAGENESIS; STREPTOCOCCUS GORDONII; THROMBOCYTE; THROMBOCYTE ADHESION;

AGGREGATION; BACTERIAL SURFACE PROTEIN; DENSE GRANULE RELEASE; PLATELET ADHESION; SHEAR ADHESION; SPREADING;

AMINO ACID MOTIFS; BACTERIAL PROTEINS; BINDING SITES; BLOOD PLATELETS; CARRIER PROTEINS; CELL DEGRANULATION; CELLS, CULTURED; ENDOCARDITIS; FIBRINOGEN; HUMANS; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEOMICS; SIGNAL TRANSDUCTION; STREPTOCOCCUS GORDONII; THROMBOSIS;

EID: 84888403247     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-07-0580     Document Type: Article

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