Mechanism of outside-in αiIbβ3-mediated activation of human platelets by the colonizing bacterium, streptococcus gordonii

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 12, 2010, Pages 2408-2415

  Keane, Ciara ^a   Petersen, Helen ^b   Reynolds, Kieran ^a   Newman, Debra K ^c,d   Cox, Dermot ^a   Jenkinson, Howard F ^b   Newman, Peter J ^a,c,d   Kerrigan, Steven W ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c BLOOD RESEARCH INSTITUTE   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

F RIIa; infective endocarditis; ITAM; platelet spreading; Streptococcus gordonii

Indexed keywords

ALPHA2BBETA3 INTEGRIN; GLYCOPROTEIN IB ALPHA; INTEGRIN; PROTEIN A; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIUM ADHERENCE; CELL INTERACTION; FILOPODIUM; LAMELLIPODIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STREPTOCOCCUS GORDONII; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE RELEASE REACTION; THROMBOSIS;

ADHESINS, BACTERIAL; BLOOD PLATELETS; CARRIER PROTEINS; CYTOPLASMIC GRANULES; ENDOCARDITIS, BACTERIAL; HUMANS; INTEGRIN ALPHA2; INTEGRIN BETA3; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE GLYCOPROTEINS; PHOSPHOLIPASE C GAMMA; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN-TYROSINE KINASES; RECEPTORS, IGG; SIGNAL TRANSDUCTION; STREPTOCOCCUS GORDONII; THROMBOSIS;

EID: 78650418323     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.216515     Document Type: Article

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