Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties

Biochemical Journal

Volumn 456, Issue 3, 2013, Pages 311-322

  Wirth, Alexander ^a   Chen, Chen Wacker ^a   Wu, Yao Wen ^b   Gorinski, Nataliya ^a   Filippov, Mikhail A ^a,c,d   Pandey, Ghanshyam ^e   Ponimaskin, Evgeni ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d LOBACHEVSKY STATE UNIVERSITY OF NIZHNY NOVGOROD   (Russian Federation)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Cdc42; Cellular morphology; Palmitoylation; Prenylation; Small GTPase

Indexed keywords

CYSTEINE; PROTEIN CDC42; SHORT HAIRPIN RNA; CDC42 PROTEIN, MOUSE; ISOENZYME;

ACTIN FILAMENT; ACYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CEREBELLUM; CONTROLLED STUDY; DENDRITIC SPINE; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HIPPOCAMPAL NEURONAL CULTURE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIPID METABOLISM; LIPIDATION; MEMBRANE BINDING; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PALMITOYLATION; PRENYLATION; PRIORITY JOURNAL; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS; SYNAPSE; TRANSCRIPTION REGULATION; ANIMAL; ANTIBODY SPECIFICITY; CYTOLOGY; DENDRITE; GENETIC TRANSCRIPTION; GENETICS; LIPOYLATION; METABOLISM; PHYSIOLOGY; PROTEIN PRENYLATION; PSEUDOPODIUM; TUMOR CELL LINE;

ANIMALS; CDC42 GTP-BINDING PROTEIN; CELL LINE, TUMOR; CEREBELLUM; CYSTEINE; DENDRITES; HIPPOCAMPUS; HUMANS; ISOENZYMES; LIPOYLATION; MICE; ORGAN SPECIFICITY; PROTEIN PRENYLATION; PSEUDOPODIA; TRANSCRIPTION, GENETIC;

EID: 84888398927     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130788     Document Type: Article

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