Pro-inflammatory cytokine-mediated ferroportin down-regulation contributes to the nigral iron accumulation in lipopolysaccharide-induced Parkinsonian models

Neuroscience

Volumn 257, Issue , 2014, Pages 20-30

  Zhang, Z ^a   Hou, L ^a   Song, J L ^b   Song, N ^a   Sun, Y J ^c   Lin, X ^a   Wang, X L ^a   Zhang, F Z ^d   Ge, Y L ^a  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b Maternal and Child Healthcare Hospital of Qingdao   (China)

^c Qingdao Cancer Hospital   (China)

^d LIAOCHENG PEOPLE'S HOSPITAL   (China)

Author keywords

Ferroportin; Heme oxygenase 1; Inflammation; Iron accumulation; Parkinson's disease; Pro inflammatory cytokine

Indexed keywords

FERROPORTIN; HEME OXYGENASE; INTERLEUKIN 1; INTERLEUKIN 6; IRON; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL STRAIN SH SY5Y; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; FLOW CYTOMETRY; GLIA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; IRON TRANSPORT; MALE; NEUROBLASTOMA CELL; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; UPREGULATION; WESTERN BLOTTING;

CM; CONDITIONED MEDIA; CT; CYCLE TIME; ELISA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FERROPORTIN; FPN; HE; HEMATOXYLIN AND EOSIN; HEME OXYGENASE-1; HO-1; IL; INFLAMMATION; INTERLEUKIN; IRON ACCUMULATION; LIPOPOLYSACCHARIDE; LPS; PARKINSON'S DISEASE; PBS; PD; PHOSPHATE-BUFFERED SALINE; PRO-INFLAMMATORY CYTOKINE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RT-PCR; SDS-PAGE; SN; SODIUM DODECYL SULFATE-POLYACRYLAMIDE GEL ELECTROPHORESIS; SODIUM SALICYLATE; SS; SUBSTANTIA NIGRA; TH; TNF-Α; TUMOR NECROSIS FACTOR-Α; TYROSINE HYDROXYLASE;

ANALYSIS OF VARIANCE; ANIMALS; ANNEXINS; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; IRON; LIPOPOLYSACCHARIDES; MALE; NEUROBLASTOMA; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 84888395755     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.09.037     Document Type: Article

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