-
1
-
-
2442485795
-
Follicle-stimulating Hormone Activation of Hypoxia-inducible Factor-1 by the Phosphatidylinositol 3-Kinase/AKT/Ras Homolog Enriched in Brain (Rheb)/Mammalian Target of Rapamycin (mTOR) Pathway Is Necessary for Induction of Select Protein Markers of Follicular Differentiation
-
DOI 10.1074/jbc.M401235200
-
Alam H, Maizels ET, Park Y, Ghaey S, Feiger ZJ, Chandel NS & Hunzicker-Dunn M 2004 Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation. Journal of Biological Chemistry 279 19431-19440. (doi:10.1074/jbc.M401235200) (Pubitemid 38623376)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 19431-19440
-
-
Alam, H.1
Maizels, E.T.2
Park, Y.3
Ghaey, S.4
Feiger, Z.J.5
Chandel, N.S.6
Hunzicker-Dunn, M.7
-
2
-
-
84861203286
-
Mammary cancer promotion by ovarian hormones involves IGFR/AKT/mTOR signaling
-
doi:10.1016/j.steroids.2012.03.009
-
Arumugam A, Parada J & Rajkumar L 2012 Mammary cancer promotion by ovarian hormones involves IGFR/AKT/mTOR signaling. Steroids 77 791-797. (doi:10.1016/j.steroids.2012.03.009)
-
(2012)
Steroids
, vol.77
, pp. 791-797
-
-
Arumugam, A.1
Parada, J.2
Rajkumar, L.3
-
3
-
-
0034028352
-
Mammalian follicular development and atresia: Role of apoptosis
-
Asselin E, Xiao CW, Wang YF & Tsang BK 2000 Mammalian follicular development and atresia: role of apoptosis. Biological Signals and Receptors 9 87-95. (doi:10.1159/000014627) (Pubitemid 30301433)
-
(2000)
Biological Signals and Receptors
, vol.9
, Issue.2
, pp. 87-95
-
-
Asselin, E.1
Xiao, C.W.2
Wang, Y.F.3
Tsang, B.K.4
-
4
-
-
0035020260
-
X-linked inhibitor of apoptosis protein activates the phosphatidylinositol 3-kinase/Akt pathway in rat granulosa cells during follicular development
-
DOI 10.1210/en.142.6.2451
-
Asselin E, Wang Y & Tsang BK 2001 X-linked inhibitor of apoptosis protein activates the phosphatidylinositol 3-kinase/Akt pathway in rat granulosa cells during follicular development. Endocrinology 142 2451-2457. (doi:10.1210/en.142.6.2451) (Pubitemid 32473101)
-
(2001)
Endocrinology
, vol.142
, Issue.6
, pp. 2451-2457
-
-
Asselin, E.1
Wang, Y.2
Tsang, B.K.3
-
5
-
-
0028891999
-
Identification of a deoxyribonuclease I-like endonuclease in rat granulosa and luteal cell nuclei
-
doi:10.1095/biolreprod53.5.1057
-
Boone DL, Yan W & Tsang BK 1995 Identification of a deoxyribonuclease I-like endonuclease in rat granulosa and luteal cell nuclei. Biology of Reproduction 53 1057-1065. (doi:10.1095/biolreprod53.5.1057)
-
(1995)
Biology of Reproduction
, vol.53
, pp. 1057-1065
-
-
Boone, D.L.1
Yan, W.2
Tsang, B.K.3
-
6
-
-
0002334077
-
Atresia
-
Eds FR Midgley & WA Sadler. New York: Plenum Press
-
Byskov AG 1979 Atresia. In Ovarian Follicular Development and Function, pp 41-58. Eds FR Midgley & WA Sadler. New York: Plenum Press.
-
(1979)
Ovarian Follicular Development and Function
, pp. 41-58
-
-
Byskov, A.G.1
-
7
-
-
78751556979
-
Autophagy as a therapeutic target in cancer
-
doi:10.4161/cbt.11.2.14622
-
Chen N & Karantza V 2011 Autophagy as a therapeutic target in cancer. Cancer Biology & Therapy 11 157-168. (doi:10.4161/cbt.11.2.14622)
-
(2011)
Cancer Biology & Therapy
, vol.11
, pp. 157-168
-
-
Chen, N.1
Karantza, V.2
-
8
-
-
77952112061
-
The role of autophagy in follicular development and atresia in rat granulosa cells
-
doi:10.1016/j.fertnstert.2009.11.021
-
Choi JY, Jo MW, Lee EY, Yoon BK & Choi DS 2010 The role of autophagy in follicular development and atresia in rat granulosa cells. Fertility and Sterility 93 2532-2537. (doi:10.1016/j.fertnstert.2009.11.021)
-
(2010)
Fertility and Sterility
, vol.93
, pp. 2532-2537
-
-
Choi, J.Y.1
Jo, M.W.2
Lee, E.Y.3
Yoon, B.K.4
Choi, D.S.5
-
9
-
-
79952441038
-
Induction of apoptotic cell death via accumulation of autophagosomes in rat granulosa cells
-
doi:10.1016/j.fertnstert.2010.06.006
-
Choi J, Jo M, Lee E & Choi D 2011a Induction of apoptotic cell death via accumulation of autophagosomes in rat granulosa cells. Fertility and Sterility 95 1482-1486. (doi:10.1016/j.fertnstert.2010.06.006)
-
(2011)
Fertility and Sterility
, vol.95
, pp. 1482-1486
-
-
Choi, J.1
Jo, M.2
Lee, E.3
Choi, D.4
-
10
-
-
80052552886
-
The role of autophagy in corpus luteum regression in the rat
-
doi:10.1095/ biolreprod.111.091314
-
Choi J, Jo M, Lee E & Choi D 2011b The role of autophagy in corpus luteum regression in the rat. Biology of Reproduction 85 465-472. (doi:10.1095/ biolreprod.111.091314)
-
(2011)
Biology of Reproduction
, vol.85
, pp. 465-472
-
-
Choi, J.1
Jo, M.2
Lee, E.3
Choi, D.4
-
11
-
-
70349969648
-
Apoptosis and autophagy: Targeting autophagy signalling in cancer cells-'trick or treats'?
-
doi:10.1111/j.1742-4658.2009.07332.x
-
Corcelle EA, Puustinen P & Jaattela M 2009 Apoptosis and autophagy: targeting autophagy signalling in cancer cells-'trick or treats'? FEBS Journal 276 6084-6096. (doi:10.1111/j.1742-4658.2009.07332.x)
-
(2009)
FEBS Journal
, vol.276
, pp. 6084-6096
-
-
Corcelle, E.A.1
Puustinen, P.2
Jaattela, M.3
-
12
-
-
65249109900
-
Autophagy, an Achilles' heel AKTing against cancer?
-
doi:10.4161/auto.5.3.7827
-
Degtyarev M, De Maziere A, Klumperman J & Lin K 2009 Autophagy, an Achilles' heel AKTing against cancer? Autophagy 5 415-418. (doi:10.4161/auto.5. 3.7827)
-
(2009)
Autophagy
, vol.5
, pp. 415-418
-
-
Degtyarev, M.1
De Maziere, A.2
Klumperman, J.3
Lin, K.4
-
13
-
-
0024728391
-
Biochemical and histological validation of a model to study follicular atresia in rats
-
Dhanasekaran N & Moudgal NR 1989 Biochemical and histological validation of a model to study follicular atresia in rats. Endocrinologia Experimentalis 23 155-166.
-
(1989)
Endocrinologia Experimentalis
, vol.23
, pp. 155-166
-
-
Dhanasekaran, N.1
Moudgal, N.R.2
-
14
-
-
33746058246
-
Lectin-like oxidized low-density lipoprotein receptor-1-mediated autophagy in human granulosa cells as an alternative of programmed cell death
-
DOI 10.1210/en.2006-0088
-
Duerrschmidt N, Zabirnyk O, Nowicki M, Ricken A, Hmeidan FA, Blumenauer V, Borlak J & Spanel-Borowski K 2006 Lectin-like oxidized low-density lipoprotein receptor-1-mediated autophagy in human granulosa cells as an alternative of programmed cell death. Endocrinology 147 3851-3860. (doi:10.1210/en.2006-0088) (Pubitemid 44079390)
-
(2006)
Endocrinology
, vol.147
, Issue.8
, pp. 3851-3860
-
-
Duerrschmidt, N.1
Zabirnyk, O.2
Nowicki, M.3
Ricken, A.4
Hmeidan, F.A.5
Blumenauer, V.6
Borlak, J.7
Spanel-Borowski, K.8
-
15
-
-
35848959917
-
Akt inhibitor shows anticancer and radiosensitizing effects in malignant glioma cells by inducing autophagy
-
Fujiwara K, Iwado E, Mills GB, Sawaya R, Kondo S & Kondo Y 2007 Akt inhibitor shows anticancer and radiosensitizing effects in malignant glioma cells by inducing autophagy. International Journal of Oncology 31 753-760.
-
(2007)
International Journal of Oncology
, vol.31
, pp. 753-760
-
-
Fujiwara, K.1
Iwado, E.2
Mills, G.B.3
Sawaya, R.4
Kondo, S.5
Kondo, Y.6
-
16
-
-
0026356114
-
Development of follicles in the mammalian ovary
-
Hirshfield AN 1991 Development of follicles in the mammalian ovary. International Review of Cytology 124 43-101.
-
(1991)
International Review of Cytology
, vol.124
, pp. 43-101
-
-
Hirshfield, A.N.1
-
17
-
-
0006815297
-
Targeted overexpression of Bcl-2 in ovaries of transgenic mice leads to decreased follicle apoptosis, enhanced folliculogenesis, and increased germ cell tumorigenesis
-
DOI 10.1210/en.137.11.4837
-
Hsu SY, Lai RJ, Finegold M & Hsueh AJ 1996 Targeted overexpression of Bcl-2 in ovaries of transgenic mice leads to decreased follicle apoptosis, enhanced folliculogenesis, and increased germ cell tumorigenesis. Endocrinology 137 4837-4843. (doi:10.1210/en.137.11.4837) (Pubitemid 26403325)
-
(1996)
Endocrinology
, vol.137
, Issue.11
, pp. 4837-4843
-
-
Hsu, S.Y.1
Lai, R.J.-M.2
Finegold, M.3
Hsueh, A.J.W.4
-
18
-
-
0025751695
-
Biochemical identification of apoptosis (programmed cell death) in granulosa cells: Evidence for a potential mechanism underlying follicular atresia
-
doi:10.1210/endo-129-5-2415
-
Hughes FM Jr & GorospeWC 1991 Biochemical identification of apoptosis (programmed cell death) in granulosa cells: evidence for a potential mechanism underlying follicular atresia. Endocrinology 129 2415-2422. (doi:10.1210/endo- 129-5-2415)
-
(1991)
Endocrinology
, vol.129
, pp. 2415-2422
-
-
Hughes Jr., F.M.1
Gorospe, W.C.2
-
19
-
-
84868122919
-
PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells
-
doi:10.1073/pnas.1205661109
-
Hunzicker-Dunn ME, Lopez-Biladeau B, Law NC, Fiedler SE, Carr DW & Maizels ET 2012 PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells. PNAS 109 E2979-E2988. (doi:10.1073/pnas.1205661109)
-
(2012)
PNAS
, vol.109
-
-
Hunzicker-Dunn, M.E.1
Lopez-Biladeau, B.2
Law, N.C.3
Fiedler, S.E.4
Carr, D.W.5
Maizels, E.T.6
-
20
-
-
33747863220
-
Insulin-like growth factor-1 and TNF-α regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
-
DOI 10.1111/j.1440-1711.2006.01454.x
-
Jia G, ChengG,GangaharDM&AgrawalDK 2006 Insulin-like growth factor-1 and TNF-a regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells. Immunology and Cell Biology 84 448-454. (doi:10.1111/j.1440-1711.2006.01454.x) (Pubitemid 44286038)
-
(2006)
Immunology and Cell Biology
, vol.84
, Issue.5
, pp. 448-454
-
-
Jia, G.1
Cheng, G.2
Gangahar, D.M.3
Agrawal, D.K.4
-
21
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
doi:10.1093/emboj/19.21.5720
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y & Yoshimori T 2000 LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO Journal 19 5720-5728. (doi:10.1093/emboj/19.21.5720)
-
(2000)
EMBO Journal
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
22
-
-
3242888703
-
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
-
DOI 10.1242/jcs.01131
-
Kabeya Y, Mizushima N, Yamamoto A, Oshitani-Okamoto S, Ohsumi Y & Yoshimori T 2004 LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. Journal of Cell Science 117 2805-2812. (doi:10.1242/jcs.01131) (Pubitemid 38997262)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2805-2812
-
-
Kabeya, Y.1
Mizushima, N.2
Yamamoto, A.3
Oshitani-Okamoto, S.4
Ohsumi, Y.5
Yoshimori, T.6
-
23
-
-
0033604585
-
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
-
doi:10.1006/excr.1999.4690
-
Kandel ES & Hay N 1999 The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Experimental Cell Research 253 210-229. (doi:10.1006/excr.1999.4690)
-
(1999)
Experimental Cell Research
, vol.253
, pp. 210-229
-
-
Kandel, E.S.1
Hay, N.2
-
24
-
-
34547124065
-
Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinase-dependent pathway in rat granulosa cells
-
DOI 10.1210/en.2007-0202
-
Kayampilly PP & Menon KM 2007 Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinase-dependent pathway in rat granulosa cells. Endocrinology 148 3950-3957. (doi:10.1210/en. 2007-0202) (Pubitemid 47105853)
-
(2007)
Endocrinology
, vol.148
, Issue.8
, pp. 3950-3957
-
-
Kayampilly, P.P.1
Menon, K.M.J.2
-
25
-
-
0033316264
-
Involvement of the Fas/Fas ligand system in p53-mediated granulosa cell apoptosis during follicular development and atresia
-
Kim JM, Yoon YD & Tsang BK 1999 Involvement of the Fas/Fas ligand system in p53-mediated granulosa cell apoptosis during follicular development and atresia. Endocrinology 140 2307-2317. (doi:10.1210/ en.140.5.2307) (Pubitemid 30636472)
-
(1999)
Endocrinology
, vol.140
, Issue.5
, pp. 2307-2317
-
-
Kim, J.-M.1
Yoon, Y.-D.2
Tsang, B.K.3
-
26
-
-
75149129007
-
PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway
-
doi:10.1093/jmcb/ mjp002
-
Li C, Liu H, Sun Y, Wang H, Guo F, Rao S, Deng J, Zhang Y, Miao Y, Guo C et al. 2009 PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. Journal of Molecular Cell Biology 1 37-45. (doi:10.1093/jmcb/ mjp002)
-
(2009)
Journal of Molecular Cell Biology
, vol.1
, pp. 37-45
-
-
Li, C.1
Liu, H.2
Sun, Y.3
Wang, H.4
Guo, F.5
Rao, S.6
Deng, J.7
Zhang, Y.8
Miao, Y.9
Guo, C.10
-
27
-
-
0036253107
-
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation
-
DOI 10.1247/csf.27.29
-
Nara A, Mizushima N, Yamamoto A, Kabeya Y, Ohsumi Y & Yoshimori T 2002 SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation. Cell Structure and Function 27 29-37. (doi:10.1247/csf.27.29) (Pubitemid 34498352)
-
(2002)
Cell Structure and Function
, vol.27
, Issue.1
, pp. 29-37
-
-
Nara, A.1
Mizushima, N.2
Yamamoto, A.3
Kabeya, Y.4
Ohsumi, Y.5
Yoshimori, T.6
-
28
-
-
77953506788
-
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy
-
doi:10.4161/auto.6.2.11062
-
Qin L, Wang Z, Tao L & Wang Y 2010 ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy 6 239-247. (doi:10.4161/auto.6.2.11062)
-
(2010)
Autophagy
, vol.6
, pp. 239-247
-
-
Qin, L.1
Wang, Z.2
Tao, L.3
Wang, Y.4
-
29
-
-
27544500981
-
Growing roles for the mTOR pathway
-
DOI 10.1016/j.ceb.2005.09.009, PII S0955067405001481
-
Sarbassov DD, Ali SM & Sabatini DM 2005 Growing roles for the mTOR pathway. Current Opinion in Cell Biology 17 596-603. (doi:10.1016/j. ceb.2005.09.009) (Pubitemid 41540408)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.6
, pp. 596-603
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sabatini, D.M.3
-
30
-
-
70349637019
-
Granulosa cell subtypes respond by autophagy or cell death to oxLDL-dependent activation of the oxidized lipoprotein receptor 1 and toll-like 4 receptor
-
doi:10.4161/auto.5.7.9507
-
Serke H, Vilser C, NowickiM, Hmeidan FA, Blumenauer V, Hummitzsch K, Losche A & Spanel-Borowski K 2009 Granulosa cell subtypes respond by autophagy or cell death to oxLDL-dependent activation of the oxidized lipoprotein receptor 1 and toll-like 4 receptor. Autophagy 5 991-1003. (doi:10.4161/auto.5.7.9507)
-
(2009)
Autophagy
, vol.5
, pp. 991-1003
-
-
Serke, H.1
Vilser, C.2
Nowicki, M.3
Hmeidan, F.A.4
Blumenauer, V.5
Hummitzsch, K.6
Losche, A.7
Spanel-Borowski, K.8
-
31
-
-
0028891851
-
Expression of members of the bcl-2 gene family in the immature rat ovary: Equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels
-
doi:10.1210/en. 136.1.232
-
Tilly JL, Tilly KI, Kenton ML & Johnson AL 1995 Expression of members of the bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels. Endocrinology 136 232-241. (doi:10.1210/en. 136.1.232)
-
(1995)
Endocrinology
, vol.136
, pp. 232-241
-
-
Tilly, J.L.1
Tilly, K.I.2
Kenton, M.L.3
Johnson, A.L.4
-
32
-
-
77952102000
-
The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, age, and body weight
-
doi:10.1016/j.fertnstert.2009.02.038
-
Vilser C, Hueller H, Nowicki M, Hmeidan FA, Blumenauer V & Spanel-Borowski K 2010 The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, age, and body weight. Fertility and Sterility 93 2706-2715. (doi:10.1016/j.fertnstert. 2009.02.038)
-
(2010)
Fertility and Sterility
, vol.93
, pp. 2706-2715
-
-
Vilser, C.1
Hueller, H.2
Nowicki, M.3
Hmeidan, F.A.4
Blumenauer, V.5
Spanel-Borowski, K.6
-
33
-
-
69449092724
-
Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy
-
Wu YT, Tan HL, Huang Q, Ong CN & Shen HM 2009 Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy. Autophagy 5 824-834.
-
(2009)
Autophagy
, vol.5
, pp. 824-834
-
-
Wu, Y.T.1
Tan, H.L.2
Huang, Q.3
Ong, C.N.4
Shen, H.M.5
-
34
-
-
77950286070
-
Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: Role of phosphatidylinositol 3-kinaseakt pathway
-
doi:10.1210/ en.2009-1048
-
Yu J, Akishita M, Eto M, Ogawa S, Son BK, Kato S, Ouchi Y & Okabe T 2010 Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: role of phosphatidylinositol 3-kinase/akt pathway. Endocrinology 151 1822-1828. (doi:10.1210/ en.2009-1048)
-
(2010)
Endocrinology
, vol.151
, pp. 1822-1828
-
-
Yu, J.1
Akishita, M.2
Eto, M.3
Ogawa, S.4
Son, B.K.5
Kato, S.6
Ouchi, Y.7
Okabe, T.8
-
35
-
-
82655168783
-
TSC1/TSC2 inactivation inhibits AKT through mTORC1-dependent up-regulation of STAT3-PTEN cascade
-
doi:10.1016/ j.canlet.2011.09.006
-
Zha X, Hu Z, He S, Wang F, Shen H & Zhang H 2011 TSC1/TSC2 inactivation inhibits AKT through mTORC1-dependent up-regulation of STAT3-PTEN cascade. Cancer Letters 313 211-217. (doi:10.1016/ j.canlet.2011.09.006)
-
(2011)
Cancer Letters
, vol.313
, pp. 211-217
-
-
Zha, X.1
Hu, Z.2
He, S.3
Wang, F.4
Shen, H.5
Zhang, H.6
|