-
1
-
-
77949497609
-
Heme scavenging and the other facets of hemopexin
-
Tolosano, E., S. Fagoonee, N. Morello, F. Vinchi, and V. Fiorito. 2010. Heme scavenging and the other facets of hemopexin. Antioxid. Redox Signal. 12: 305-320.
-
(2010)
Antioxid. Redox Signal.
, vol.12
, pp. 305-320
-
-
Tolosano, E.1
Fagoonee, S.2
Morello, N.3
Vinchi, F.4
Fiorito, V.5
-
2
-
-
0027391548
-
Evidence for the localization of haemopexin immunoreactivity in neurones in the human brain
-
Morris, C. M., J. M. Candy, J. A. Edwardson, C. A. Bloxham, and A. Smith. 1993. Evidence for the localization of haemopexin immunoreactivity in neurones in the human brain. Neurosci. Lett. 149: 141-144.
-
(1993)
Neurosci. Lett.
, vol.149
, pp. 141-144
-
-
Morris, C.M.1
Candy, J.M.2
Edwardson, J.A.3
Bloxham, C.A.4
Smith, A.5
-
3
-
-
0030017273
-
Hemopexin in the human retina: Protection of the retina against heme-mediated toxicity
-
Hunt, R. C., D. M. Hunt, N. Gaur, and A. Smith. 1996. Hemopexin in the human retina: protection of the retina against heme-mediated toxicity. J. Cell. Physiol. 168: 71-80.
-
(1996)
J. Cell. Physiol.
, vol.168
, pp. 71-80
-
-
Hunt, R.C.1
Hunt, D.M.2
Gaur, N.3
Smith, A.4
-
4
-
-
77449150120
-
Haemopexin affects iron distribution and ferritin expression in mouse brain
-
Morello, N., E. Tonoli, F. Logrand, V. Fiorito, S. Fagoonee, E. Turco, L. Silengo, A. Vercelli, F. Altruda, and E. Tolosano. 2009. Haemopexin affects iron distribution and ferritin expression in mouse brain. J. Cell. Mol. Med. 13: 4192-4204.
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 4192-4204
-
-
Morello, N.1
Tonoli, E.2
Logrand, F.3
Fiorito, V.4
Fagoonee, S.5
Turco, E.6
Silengo, L.7
Vercelli, A.8
Altruda, F.9
Tolosano, E.10
-
5
-
-
65549152427
-
Heme-hemopexin complex attenuates neuronal cell death and stroke damage
-
Li, R. C., S. Saleem, G. Zhen, W. Cao, H. Zhuang, J. Lee, A. Smith, F. Altruda, E. Tolosano, and S. Doré. 2009. Heme-hemopexin complex attenuates neuronal cell death and stroke damage. J. Cereb. Blood Flow Metab. 29: 953-964.
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 953-964
-
-
Li, R.C.1
Saleem, S.2
Zhen, G.3
Cao, W.4
Zhuang, H.5
Lee, J.6
Smith, A.7
Altruda, F.8
Tolosano, E.9
Doré, S.10
-
6
-
-
0032958691
-
Regulation of hemopexin synthesis in degenerating and regenerating rat sciatic nerve
-
Madore, N., L. Camborieux, N. Bertrand, and J. P. Swerts. 1999. Regulation of hemopexin synthesis in degenerating and regenerating rat sciatic nerve. J. Neurochem. 72: 708-715.
-
(1999)
J. Neurochem.
, vol.72
, pp. 708-715
-
-
Madore, N.1
Camborieux, L.2
Bertrand, N.3
Swerts, J.P.4
-
7
-
-
0034632157
-
Respective roles of inflammation and axonal breakdown in the regulation of peripheral nerve hemopexin: An analysis in rats and in C57BL/Wlds mice
-
Camborieux, L., V. Julia, B. Pipy, and J. P. Swerts. 2000. Respective roles of inflammation and axonal breakdown in the regulation of peripheral nerve hemopexin: an analysis in rats and in C57BL/Wlds mice. J. Neuroimmunol. 107: 29-41.
-
(2000)
J. Neuroimmunol.
, vol.107
, pp. 29-41
-
-
Camborieux, L.1
Julia, V.2
Pipy, B.3
Swerts, J.P.4
-
8
-
-
0026669745
-
Hemopexin is synthesized in peripheral nerves but not in central nervous system and accumulates after axotomy
-
Swerts, J. P., C. Soula, Y. Sagot, M. J. Guinaudy, J. C. Guillemot, P. Ferrara, A. M. Duprat, and P. Cochard. 1992. Hemopexin is synthesized in peripheral nerves but not in central nervous system and accumulates after axotomy. J. Biol. Chem. 267: 10596-10600.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 10596-10600
-
-
Swerts, J.P.1
Soula, C.2
Sagot, Y.3
Guinaudy, M.J.4
Guillemot, J.C.5
Ferrara, P.6
Duprat, A.M.7
Cochard, P.8
-
9
-
-
0036424643
-
Identification of proteins in human cerebrospinal fluid using liquid-phase isoelectric focusing as a prefractionation step followed by two-dimensional gel electrophoresis and matrixassisted laser desorption/ionisation mass spectrometry
-
Davidsson, P., S. Folkesson, M. Christiansson, M. Lindbjer, B. Dellheden, K. Blennow, and A. Westman-Brinkmalm. 2002. Identification of proteins in human cerebrospinal fluid using liquid-phase isoelectric focusing as a prefractionation step followed by two-dimensional gel electrophoresis and matrixassisted laser desorption/ionisation mass spectrometry. Rapid Commun. Mass Spectrom. 16: 2083-2088.
-
(2002)
Rapid Commun. Mass Spectrom.
, vol.16
, pp. 2083-2088
-
-
Davidsson, P.1
Folkesson, S.2
Christiansson, M.3
Lindbjer, M.4
Dellheden, B.5
Blennow, K.6
Westman-Brinkmalm, A.7
-
10
-
-
33645776682
-
Comparative proteomics of cerebrospinal fluid in neuropathologically- confirmed Alzheimer's disease and non-demented elderly subjects
-
Castaño, E. M., A. E. Roher, C. L. Esh, T. A. Kokjohn, and T. Beach. 2006. Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects. Neurol. Res. 28: 155-163.
-
(2006)
Neurol. Res.
, vol.28
, pp. 155-163
-
-
Castaño, E.M.1
Roher, A.E.2
Esh, C.L.3
Kokjohn, T.A.4
Beach, T.5
-
11
-
-
46749135674
-
Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload
-
Vinchi, F., S. Gastaldi, L. Silengo, F. Altruda, and E. Tolosano. 2008. Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload. Am. J. Pathol. 173: 289-299.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 289-299
-
-
Vinchi, F.1
Gastaldi, S.2
Silengo, L.3
Altruda, F.4
Tolosano, E.5
-
12
-
-
69449086963
-
Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages
-
Liang, X., T. Lin, G. Sun, L. Beasley-Topliffe, J. M. Cavaillon, and H. S. Warren. 2009. Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages. J. Leukoc. Biol. 86: 229-235.
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 229-235
-
-
Liang, X.1
Lin, T.2
Sun, G.3
Beasley-Topliffe, L.4
Cavaillon, J.M.5
Warren, H.S.6
-
13
-
-
84864809340
-
Identification of hemopexin as an anti-inflammatory factor that inhibits synergy of hemoglobin with HMGB1 in sterile and infectious inflammation
-
Lin, T., F. Sammy, H. Yang, S. Thundivalappil, J. Hellman, K. J. Tracey, and H. S. Warren. 2012. Identification of hemopexin as an anti-inflammatory factor that inhibits synergy of hemoglobin with HMGB1 in sterile and infectious inflammation. J. Immunol. 189: 2017-2022.
-
(2012)
J. Immunol.
, vol.189
, pp. 2017-2022
-
-
Lin, T.1
Sammy, F.2
Yang, H.3
Thundivalappil, S.4
Hellman, J.5
Tracey, K.J.6
Warren, H.S.7
-
14
-
-
63449122537
-
Protein expression profiles in pediatric multiple sclerosis: Potential biomarkers
-
Rithidech, K. N., L. Honikel, M. Milazzo, D. Madigan, R. Troxell, and L. B. Krupp. 2009. Protein expression profiles in pediatric multiple sclerosis: potential biomarkers. Mult. Scler. 15: 455-464.
-
(2009)
Mult. Scler.
, vol.15
, pp. 455-464
-
-
Rithidech, K.N.1
Honikel, L.2
Milazzo, M.3
Madigan, D.4
Troxell, R.5
Krupp, L.B.6
-
15
-
-
0034727066
-
Multiple sclerosis
-
Noseworthy, J. H., C. Lucchinetti, M. Rodriguez, and B. G. Weinshenker. 2000. Multiple sclerosis. N. Engl. J. Med. 343: 938-952.
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 938-952
-
-
Noseworthy, J.H.1
Lucchinetti, C.2
Rodriguez, M.3
Weinshenker, B.G.4
-
16
-
-
33644607018
-
Multiple sclerosis - The plaque and its pathogenesis
-
Frohman, E. M., M. K. Racke, and C. S. Raine. 2006. Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 354: 942-955.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 942-955
-
-
Frohman, E.M.1
Racke, M.K.2
Raine, C.S.3
-
17
-
-
84862635336
-
Will the real multiple sclerosis please stand up?
-
Stys, P. K., G. W. Zamponi, J. van Minnen, and J. J. Geurts. 2012. Will the real multiple sclerosis please stand up? Nat. Rev. Neurosci. 13: 507-514.
-
(2012)
Nat. Rev. Neurosci.
, vol.13
, pp. 507-514
-
-
Stys, P.K.1
Zamponi, G.W.2
Van Minnen, J.3
Geurts, J.J.4
-
18
-
-
0030240326
-
The central nervous system as an immunocompetent organ: Role of glial cells in antigen presentation
-
Shrikant, P., and E. N. Benveniste. 1996. The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation. J. Immunol. 157: 1819-1822.
-
(1996)
J. Immunol.
, vol.157
, pp. 1819-1822
-
-
Shrikant, P.1
Benveniste, E.N.2
-
19
-
-
51249090471
-
T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis
-
Hedegaard, C. J., M. Krakauer, K. Bendtzen, H. Lund, F. Sellebjerg, and C. H. Nielsen. 2008. T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis. Immunology 125: 161-169.
-
(2008)
Immunology
, vol.125
, pp. 161-169
-
-
Hedegaard, C.J.1
Krakauer, M.2
Bendtzen, K.3
Lund, H.4
Sellebjerg, F.5
Nielsen, C.H.6
-
20
-
-
46949104323
-
IL-12-and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke, M. A., T. J. Carlson, A. V. Andjelkovic, and B. M. Segal. 2008. IL-12-and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J. Exp. Med. 205: 1535-1541.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
21
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes, I. M., L. M. Cerretti, D. Liggitt, R. A. Harris, and J. M. Goverman. 2008. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat. Med. 14: 337-342.
-
(2008)
Nat. Med.
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
22
-
-
67249090787
-
T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta
-
Durelli, L., L. Conti, M. Clerico, D. Boselli, G. Contessa, P. Ripellino, B. Ferrero, P. Eid, and F. Novelli. 2009. T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta. Ann. Neurol. 65: 499-509.
-
(2009)
Ann. Neurol.
, vol.65
, pp. 499-509
-
-
Durelli, L.1
Conti, L.2
Clerico, M.3
Boselli, D.4
Contessa, G.5
Ripellino, P.6
Ferrero, B.7
Eid, P.8
Novelli, F.9
-
23
-
-
0033485566
-
Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice
-
Tolosano, E., E. Hirsch, E. Patrucco, C. Camaschella, R. Navone, L. Silengo, and F. Altruda. 1999. Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. Blood 94: 3906-3914.
-
(1999)
Blood
, vol.94
, pp. 3906-3914
-
-
Tolosano, E.1
Hirsch, E.2
Patrucco, E.3
Camaschella, C.4
Navone, R.5
Silengo, L.6
Altruda, F.7
-
24
-
-
82955228112
-
T(H)17 cytokines in autoimmune neuroinflammation
-
Becher, B., and B. M. Segal. 2011. T(H)17 cytokines in autoimmune neuroinflammation. Curr. Opin. Immunol. 23: 707-712.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 707-712
-
-
Becher, B.1
Segal, B.M.2
-
25
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir, H., K. Kreymborg, I. Ifergan, A. Dodelet-Devillers, R. Cayrol, M. Bernard, F. Giuliani, N. Arbour, B. Becher, and A. Prat. 2007. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat. Med. 13: 1173-1175.
-
(2007)
Nat. Med.
, vol.13
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
Dodelet-Devillers, A.4
Cayrol, R.5
Bernard, M.6
Giuliani, F.7
Arbour, N.8
Becher, B.9
Prat, A.10
-
26
-
-
49649084476
-
Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice
-
Fagoonee, S., C. Caorsi, M. Giovarelli, M. Stoltenberg, L. Silengo, F. Altruda, G. Camussi, E. Tolosano, and B. Bussolati. 2008. Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice. J. Immunol. 181: 1937-1947.
-
(2008)
J. Immunol.
, vol.181
, pp. 1937-1947
-
-
Fagoonee, S.1
Caorsi, C.2
Giovarelli, M.3
Stoltenberg, M.4
Silengo, L.5
Altruda, F.6
Camussi, G.7
Tolosano, E.8
Bussolati, B.9
-
27
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington, L. E., R. D. Hatton, P. R. Mangan, H. Turner, T. L. Murphy, K. M. Murphy, and C. T. Weaver. 2005. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6: 1123-1132.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
28
-
-
84856566853
-
Th17 cells in multiple sclerosis express higher levels of JAK2, which increases their surface expression of IFN-gR2
-
Conti, L., R. De Palma, S. Rolla, D. Boselli, G. Rodolico, S. Kaur, O. Silvennoinen, E. Niccolai, A. Amedei, F. Ivaldi, et al. 2012. Th17 cells in multiple sclerosis express higher levels of JAK2, which increases their surface expression of IFN-gR2. J. Immunol. 188: 1011-1018.
-
(2012)
J. Immunol.
, vol.188
, pp. 1011-1018
-
-
Conti, L.1
De Palma, R.2
Rolla, S.3
Boselli, D.4
Rodolico, G.5
Kaur, S.6
Silvennoinen, O.7
Niccolai, E.8
Amedei, A.9
Ivaldi, F.10
-
29
-
-
32344453016
-
IFNgammaR2 trafficking tunes IFNgamma-STAT1 signaling in T lymphocytes
-
Regis, G., L. Conti, D. Boselli, and F. Novelli. 2006. IFNgammaR2 trafficking tunes IFNgamma-STAT1 signaling in T lymphocytes. Trends Immunol. 27: 96-101.
-
(2006)
Trends Immunol.
, vol.27
, pp. 96-101
-
-
Regis, G.1
Conti, L.2
Boselli, D.3
Novelli, F.4
-
30
-
-
17044423074
-
Iron regulates T-lymphocyte sensitivity to the IFN-gamma/STAT1 signaling pathway in vitro and in vivo
-
Regis, G., M. Bosticardo, L. Conti, S. De Angelis, D. Boselli, B. Tomaino, P. Bernabei, M. Giovarelli, and F. Novelli. 2005. Iron regulates T-lymphocyte sensitivity to the IFN-gamma/STAT1 signaling pathway in vitro and in vivo. Blood 105: 3214-3221.
-
(2005)
Blood
, vol.105
, pp. 3214-3221
-
-
Regis, G.1
Bosticardo, M.2
Conti, L.3
De Angelis, S.4
Boselli, D.5
Tomaino, B.6
Bernabei, P.7
Giovarelli, M.8
Novelli, F.9
-
31
-
-
0032534730
-
IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: Roles of IL-6 in the activation and differentiation of autoreactive T cells
-
Samoilova, E. B., J. L. Horton, B. Hilliard, T. S. Liu, and Y. Chen. 1998. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J. Immunol. 161: 6480-6486.
-
(1998)
J. Immunol.
, vol.161
, pp. 6480-6486
-
-
Samoilova, E.B.1
Horton, J.L.2
Hilliard, B.3
Liu, T.S.4
Chen, Y.5
-
32
-
-
60549102720
-
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
-
Takatori, H., Y. Kanno, W. T. Watford, C. M. Tato, G. Weiss, I. I. Ivanov, D. R. Littman, and J. J. O'Shea. 2009. Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. J. Exp. Med. 206: 35-41.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 35-41
-
-
Takatori, H.1
Kanno, Y.2
Watford, W.T.3
Tato, C.M.4
Weiss, G.5
Ivanov, I.I.6
Littman, D.R.7
O'Shea, J.J.8
-
33
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D. J., J. Sherlock, Y. Chen, C. A. Murphy, B. Joyce, B. Seymour, L. Lucian, W. To, S. Kwan, T. Churakova, et al. 2003. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421: 744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
-
34
-
-
65549086460
-
Regulation of autoimmune encephalomyelitis by toll-like receptors
-
Marta, M., U. C. Meier, and A. Lobell. 2009. Regulation of autoimmune encephalomyelitis by toll-like receptors. Autoimmun. Rev. 8: 506-509.
-
(2009)
Autoimmun. Rev.
, vol.8
, pp. 506-509
-
-
Marta, M.1
Meier, U.C.2
Lobell, A.3
-
35
-
-
42249109064
-
Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis
-
Marta, M., A. Andersson, M. Isaksson, O. Kämpe, and A. Lobell. 2008. Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis. Eur. J. Immunol. 38: 565-575.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 565-575
-
-
Marta, M.1
Andersson, A.2
Isaksson, M.3
Kämpe, O.4
Lobell, A.5
-
36
-
-
77952866513
-
Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease
-
Reynolds, J. M., B. P. Pappu, J. Peng, G. J. Martinez, Y. Zhang, Y. Chung, L. Ma, X. O. Yang, R. I. Nurieva, Q. Tian, and C. Dong. 2010. Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease. Immunity 32: 692-702.
-
(2010)
Immunity
, vol.32
, pp. 692-702
-
-
Reynolds, J.M.1
Pappu, B.P.2
Peng, J.3
Martinez, G.J.4
Zhang, Y.5
Chung, Y.6
Ma, L.7
Yang, X.O.8
Nurieva, R.I.9
Tian, Q.10
Dong, C.11
-
37
-
-
79957460022
-
A role for hemopexin in oligodendrocyte differentiation and myelin formation
-
Morello, N., F. T. Bianchi, P. Marmiroli, E. Tonoli, V. Rodriguez Menendez, L. Silengo, G. Cavaletti, A. Vercelli, F. Altruda, and E. Tolosano. 2011. A role for hemopexin in oligodendrocyte differentiation and myelin formation. PLoS ONE 6: e20173.
-
(2011)
PLoS ONE
, vol.6
-
-
Morello, N.1
Bianchi, F.T.2
Marmiroli, P.3
Tonoli, E.4
Rodriguez Menendez, V.5
Silengo, L.6
Cavaletti, G.7
Vercelli, A.8
Altruda, F.9
Tolosano, E.10
-
38
-
-
84864464223
-
The conundrum of iron in multiple sclerosis-time for an individualised approach
-
van Rensburg, S. J., M. J. Kotze, and R. van Toorn. 2012. The conundrum of iron in multiple sclerosis-time for an individualised approach. Metab. Brain Dis. 27: 239-253.
-
(2012)
Metab. Brain Dis.
, vol.27
, pp. 239-253
-
-
Van Rensburg, S.J.1
Kotze, M.J.2
Van Toorn, R.3
|