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Volumn 10, Issue 6, 2013, Pages 483-489

CD40 interacts directly with RAG1 and RAG2 in autoaggressive T cells and Fas prevents CD40-induced RAG expression

Author keywords

autoimmunity; CD40; Fas; RAG; T cell receptor

Indexed keywords

CD40 ANTIGEN; FAS ANTIGEN; KU ANTIGEN; RAG1 PROTEIN; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 84888321980     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2013.24     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 0029083695 scopus 로고
    • Rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent
    • Leu TM, Schatz DG. rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent. Mol Cell Biol 1995; 15: 5657-5670.
    • (1995) Mol Cell Biol , vol.15 , pp. 5657-5670
    • Leu, T.M.1    Schatz, D.G.2
  • 2
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S. Somatic generation of antibody diversity. Nature 1983; 302: 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 5
    • 0034671816 scopus 로고    scopus 로고
    • Receptor revision in peripheral T cells creates a diverse Vβ repertoire
    • McMahan CJ, Fink PJ. Receptor revisionin peripheralT cells creates a diverse V beta repertoire. J Immunol 2000; 165: 6902-6907. (Pubitemid 32001160)
    • (2000) Journal of Immunology , vol.165 , Issue.12 , pp. 6902-6907
    • McMahan, C.J.1    Fink, P.J.2
  • 7
    • 0346034786 scopus 로고    scopus 로고
    • Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: A mechanism for the generation of autoaggressive T cells in the periphery
    • Vaitaitis GM, Poulin M, Sanderson RJ, Haskins K, Wagner DH Jr. Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery. J Immunol 2003; 170: 3455-3459. (Pubitemid 36359210)
    • (2003) Journal of Immunology , vol.170 , Issue.7 , pp. 3455-3459
    • Vaitaitis, G.M.1    Poulin, M.2    Sanderson, R.J.3    Haskins, K.4    Wagner Jr., D.H.5
  • 8
    • 38449105934 scopus 로고    scopus 로고
    • Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage
    • Zehn D, Bevan MJ, Fink PJ. Cutting edge: TCR revision affects predominantly Foxp3 cells and skews them toward the Th17 lineage. J Immunol 2007; 179: 5653-5657.
    • (2007) J Immunol , vol.179 , pp. 5653-5657
    • Zehn, D.1    Bevan, M.J.2    Fink, P.J.3
  • 9
    • 0038544675 scopus 로고    scopus 로고
    • T cell receptor revision does not solely target recent thymic emigrants
    • Cooper CJ, Orr MT, McMahan CJ. Fink PJ. T cell receptor revision does not solely target recent thymic emigrants. J Immunol 2003; 171: 226-233. (Pubitemid 36745292)
    • (2003) Journal of Immunology , vol.171 , Issue.1 , pp. 226-233
    • Cooper, C.J.1    Orr, M.T.2    McMahan, C.J.3    Fink, P.J.4
  • 11
    • 34848908354 scopus 로고    scopus 로고
    • Age-dependent TCR revision mediated by interaction between alphabeta TCR and self-antigens
    • Takase M, Kanagawa EM, Kanagawa O. Age-dependent TCR revision mediated by interaction between alphabeta TCR and self-antigens. J Immunol 2007; 179: 2163-2169.
    • (2007) J Immunol , vol.179 , pp. 2163-2169
    • Takase, M.1    Kanagawa, E.M.2    Kanagawa, O.3
  • 12
    • 0033673028 scopus 로고    scopus 로고
    • Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe
    • Fink PJ, McMahan CJ. Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe. Immunol Today 2000; 21: 561-566.
    • (2000) Immunol Today , vol.21 , pp. 561-566
    • Fink, P.J.1    McMahan, C.J.2
  • 13
    • 77953425962 scopus 로고    scopus 로고
    • Cutting Edge: Rag deletion in peripheral T cells blocks TCR revision
    • Hale JS, Ames KT, Boursalian TE, Fink PJ. Cutting Edge: Rag deletion in peripheral T cells blocks TCR revision. J Immunol 2010; 184: 5964-5968.
    • (2010) J Immunol , vol.184 , pp. 5964-5968
    • Hale, J.S.1    Ames, K.T.2    Boursalian, T.E.3    Fink, P.J.4
  • 14
    • 33947207868 scopus 로고    scopus 로고
    • Re-shaping the T cell repertoire: TCR editing and TCR revision for good and for bad
    • DOI 10.1016/j.clim.2006.08.006, PII S1521661606008382
    • Wagner DH Jr. Re-shaping the T cell repertoire: TCR editing and TCR revision for good and for bad. Clin Immunol 2007; 123: 1-6. (Pubitemid 46415682)
    • (2007) Clinical Immunology , vol.123 , Issue.1 , pp. 1-6
    • Wagner Jr., D.H.1
  • 15
    • 0033194297 scopus 로고    scopus 로고
    • Increased expression of CD40 on thymocytes and peripheral T cells in autoimmunity: A mechanism for acquiring changes in the peripheral T cell receptor repertoire
    • Wagner DH Jr, Newell E, Sanderson RJ, Freed JH, Newell MK. Increased expression of CD40 on thymocytes and peripheral T cells in autoimmunity: a mechanism for acquiring changes in the peripheral T cell receptor repertoire. Int J Mol Med 1999; 4: 231-242.
    • (1999) Int J Mol Med , vol.4 , pp. 231-242
    • Wagner Jr., D.H.1    Newell, E.2    Sanderson, R.J.3    Freed, J.H.4    Newell, M.K.5
  • 17
    • 0031279105 scopus 로고    scopus 로고
    • CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice
    • Balasa B, Krahl T, Patstone G, Lee J, Tisch R, McDevitt HO et al. CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. J Immunol 1997; 159: 4620-4627. (Pubitemid 127470625)
    • (1997) Journal of Immunology , vol.159 , Issue.9 , pp. 4620-4627
    • Balasa, B.1    Krahl, T.2    Patstone, G.3    Lee, J.4    Tisch, R.5    McDevitt, H.O.6    Sarvetnick, N.7
  • 18
    • 0027816953 scopus 로고
    • Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40
    • Durie FH, Fava RA, Foy TM, Aruffo A, Ledbetter JA, Noelle RJ. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science 1993; 261: 1328-1330. (Pubitemid 24081170)
    • (1993) Science , vol.261 , Issue.5126 , pp. 1328-1330
    • Durie, F.H.1    Fava, R.A.2    Foy, T.M.3    Aruffo, A.4    Ledbetter, J.A.5    Noelle, R.J.6
  • 20
    • 33846234751 scopus 로고    scopus 로고
    • A costimulatory function for T cell CD40
    • Munroe ME, Bishop GA. A costimulatory function for T cell CD40. J Immunol 2007; 178: 671-682. (Pubitemid 46095139)
    • (2007) Journal of Immunology , vol.178 , Issue.2 , pp. 671-682
    • Munroe, M.E.1    Bishop, G.A.2
  • 21
    • 0141453661 scopus 로고    scopus 로고
    • Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis
    • DOI 10.1002/art.11230
    • Quezada SA, Eckert M, Adeyi OA, Schned AR, Noelle RJ, Burns CM. Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis. Arthritis Rheum 2003; 48: 2541-2554. (Pubitemid 37138671)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.9 , pp. 2541-2554
    • Quezada, S.A.1    Eckert, M.2    Adeyi, O.A.3    Schned, A.R.4    Noelle, R.J.5    Burns, C.M.6
  • 22
    • 12344336336 scopus 로고    scopus 로고
    • The role of CD40-CD154 interactions in autoimmunity and the benefit of disrupting this pathway
    • DOI 10.1080/08916930400002386
    • Toubi E, Shoenfeld Y. The role of CD40-CD154 interactions in autoim-munity and the benefit of disrupting this pathway. Autoimmunity 2004; 37: 457-464. (Pubitemid 40123415)
    • (2004) Autoimmunity , vol.37 , Issue.6-7 , pp. 457-464
    • Toubi, E.1    Shoenfeld, Y.2
  • 23
    • 44349086299 scopus 로고    scopus 로고
    • High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity
    • Vaitaitis GM, Wagner DH Jr. High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity. PLoS ONE 2008; 3: e2076.
    • (2008) PLoS ONE , vol.3
    • Vaitaitis, G.M.1    Wagner Jr., D.H.2
  • 24
    • 2942752011 scopus 로고    scopus 로고
    • + auto-aggressive T cell expansion during insulin-dependent diabetes mellitus
    • DOI 10.1002/eji.200324703
    • 1 auto-aggressive T cell expansion during insulin-dependent diabetes mellitus. Eur J Immunol 2004; 34: 1488-1497. (Pubitemid 39256029)
    • (2004) European Journal of Immunology , vol.34 , Issue.5 , pp. 1488-1497
    • Waid, D.M.1    Vaitaitis, G.M.2    Wagner Jr., D.H.3
  • 25
    • 0037083423 scopus 로고    scopus 로고
    • Mechanism of action of combined short-term CTLA4Ig and anti-CD40 ligand in murine systemic lupus erythematosus
    • Wang X, Huang W, Mihara M, Sinha J, Davidson A. Mechanism of action of combined short-term CTLA4Ig and anti-CD40 ligand in murine systemic lupus erythematosus. J Immunol 2002; 168: 2046-2053. (Pubitemid 34135809)
    • (2002) Journal of Immunology , vol.168 , Issue.4 , pp. 2046-2053
    • Wang, X.1    Huang, W.2    Mihara, M.3    Sinha, J.4    Davidson, A.5
  • 26
    • 0035113959 scopus 로고    scopus 로고
    • Characteristics of inflammatory cells in spontaneous autoimmune thyroiditis of NOD.H-2h4 mice
    • DOI 10.1006/jaut.2000.0458
    • Yu S, Medling B, Yagita H, Braley-Mullen H. Characteristics of inflammatory cells in spontaneous autoimmune thyroiditis of NOD. H-2h4 mice. J Autoimmun 2001; 16: 37-46. (Pubitemid 32174173)
    • (2001) Journal of Autoimmunity , vol.16 , Issue.1 , pp. 37-46
    • Yu, S.1    Medling, B.2    Yagita, H.3    Braley-Mullen, H.4
  • 31
    • 38449094444 scopus 로고    scopus 로고
    • IL-6 contributes to the expression of RAGs in human mature B cells
    • Hillion S, Dueymes M, Youinou P, Jamin C. IL-6 contributes to the expression of RAGs in human mature B cells. J Immunol 2007; 179: 6790-6798.
    • (2007) J Immunol , vol.179 , pp. 6790-6798
    • Hillion, S.1    Dueymes, M.2    Youinou, P.3    Jamin, C.4
  • 32
    • 0028041170 scopus 로고
    • Monoclonal antibodies to murine CD40 define two distinct functional epitopes
    • DOI 10.1002/eji.1830240816
    • Heath AW, Wu WW, Howard MC. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur J Immunol 1994; 24: 1828-1834. (Pubitemid 24237553)
    • (1994) European Journal of Immunology , vol.24 , Issue.8 , pp. 1828-1834
    • Heath, A.W.1    Wu, W.W.2    Howard, M.C.3
  • 33
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching
    • DOI 10.1016/S1074-7613(00)80258-7
    • Rolink A, Melchers F, Andersson J. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity 1996; 5: 319-330. (Pubitemid 26366755)
    • (1996) Immunity , vol.5 , Issue.4 , pp. 319-330
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 35
    • 77955424415 scopus 로고    scopus 로고
    • CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity
    • Vaitaitis GM, Wagner DH Jr. CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity. Mol Immunol 2010; 47: 2303-2313.
    • (2010) Mol Immunol , vol.47 , pp. 2303-2313
    • Vaitaitis, G.M.1    Wagner Jr., D.H.2
  • 36
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 37
    • 0032514701 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement
    • DiLorenzo TP, Graser RT, Ono T, Christianson GJ, Chapman HD, Roopenian DC et al. Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proc Natl Acad Sci USA 1998; 95: 12538-12543.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12538-12543
    • Dilorenzo, T.P.1    Graser, R.T.2    Ono, T.3    Christianson, G.J.4    Chapman, H.D.5    Roopenian, D.C.6
  • 38
    • 0035997348 scopus 로고    scopus 로고
    • V(D)J recombination: RAG proteins, repair factors, and regulation
    • DOI 10.1146/annurev.biochem.71.090501.150203
    • Gellert M. V(D)J recombination: RAG proteins, repair factors, and regulation. Annu Rev Biochem 2002; 71: 101-132. (Pubitemid 34800216)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 101-132
    • Gellert, M.1
  • 41
    • 0032416375 scopus 로고    scopus 로고
    • Production of pathogenic antibodies: Cognate interactions between autoimmune T and B cells
    • DOI 10.1191/096120398678920703
    • Datta SK. Production of pathogenic antibodies: cognate interactions between autoimmune T and B cells. Lupus 1998; 7: 591-596. (Pubitemid 29008224)
    • (1998) Lupus , vol.7 , Issue.9 , pp. 591-596
    • Datta, S.K.1
  • 43
    • 0031777665 scopus 로고    scopus 로고
    • Protection from insulin dependent diabetes mellitus afforded by insulin antigens in incomplete Freund's adjuvant depends on route of administration
    • DOI 10.1006/jaut.1997.0184
    • Hutchings P, Cooke A. Protection from insulin dependent diabetes mellitus afforded by insulin antigens in incomplete Freund's adjuvant depends on route of administration. J Autoimmun 1998; 11: 127-130. (Pubitemid 28273008)
    • (1998) Journal of Autoimmunity , vol.11 , Issue.2 , pp. 127-130
    • Hutchings, P.1    Cooke, A.2
  • 44
    • 33845684328 scopus 로고    scopus 로고
    • Long-term prevention of diabetes and marked suppression of insulin autoantibodies and insulitis in mice lacking native insulin B9-23 sequence
    • DOI 10.1196/annals.1375.018, Immunology of Diabetes IV: Progress in Our Understanding
    • Nakayama M, Babaya N, Miao D, Gianani R, Liu E, Elliott JF et al. Long-term prevention of diabetes and marked suppression of insulin autoantibodies and insulitis in mice lacking native insulin B9-23 sequence. Ann NY Acad Sci 2006; 1079: 122-129. (Pubitemid 44968711)
    • (2006) Annals of the New York Academy of Sciences , vol.1079 , pp. 122-129
    • Nakayama, M.1    Babaya, N.2    Miao, D.3    Gianani, R.4    Liu, E.5    Elliott, J.F.6    Eisenbarth, G.S.7
  • 46
    • 84871682813 scopus 로고    scopus 로고
    • Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes
    • Skarstrand H, Lernmark A, Vaziri-Sani F. Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes. Scand J Immunol 2013; 77: 21-29.
    • (2013) Scand J Immunol , vol.77 , pp. 21-29
    • Skarstrand, H.1    Lernmark, A.2    Vaziri-Sani, F.3
  • 48
    • 0033106415 scopus 로고    scopus 로고
    • T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides
    • DOI 10.1006/jaut.1998.0262
    • Abulafia-Lapid R, Elias D, Raz I, Keren-Zur Y, Atlan H, Cohen IR. T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides. J Autoimmun 1999; 12: 121-129. (Pubitemid 29130589)
    • (1999) Journal of Autoimmunity , vol.12 , Issue.2 , pp. 121-129
    • Abulafia-Lapid, R.1    Elias, D.2    Raz, I.3    Keren-Zur, Y.4    Atlan, H.5    Cohen, I.R.6
  • 49
    • 56549110891 scopus 로고    scopus 로고
    • CD40 on NOD CD4 T cells contributes to their activation and pathogenicity
    • Baker RL, Wagner DH Jr, Haskins K. CD40 on NOD CD4 T cells contributes to their activation and pathogenicity. J Autoimmun 2008; 31: 385-392.
    • (2008) J Autoimmun , vol.31 , pp. 385-392
    • Baker, R.L.1    Wagner Jr., D.H.2    Haskins, K.3


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