Applying the skin sensitisation adverse outcome pathway (AOP) to quantitative risk assessment

Toxicology in Vitro

Volumn 28, Issue 1, 2014, Pages 8-12

  Maxwell, Gavin ^a   MacKay, Cameron ^a   Cubberley, Richard ^a   Davies, Michael ^a   Gellatly, Nichola ^a   Glavin, Stephen ^a   Gouin, Todd ^a   Jacquoilleot, Sandrine ^a   Moore, Craig ^a   Pendlington, Ruth ^a   Saib, Ouarda ^a   Sheffield, David ^a   Stark, Richard ^a   Summerfield, Vicki ^a  

^a UNILEVER RESEARCH   (United Kingdom)

Author keywords

Adverse outcome pathway; Mathematical modelling; Risk assessment; Skin sensitisation

Indexed keywords

HAPTEN;

ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL RESEARCH; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; IMMUNE RESPONSE; MATHEMATICAL MODEL; MEDICAL DECISION MAKING; PREDICTION; QUALITY CONTROL; RISK ASSESSMENT; SKIN SENSITISATION ADVERSE OUTCOME PATHWAY; SKIN SENSITIZATION; SKIN TEST;

ANIMALIA;

ADVERSE OUTCOME PATHWAY; MATHEMATICAL MODELLING; RISK ASSESSMENT; SKIN SENSITISATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BENCHMARKING; CD8-POSITIVE T-LYMPHOCYTES; DERMATITIS, ALLERGIC CONTACT; HUMANS; MODELS, THEORETICAL; PROTEIN BINDING; RISK ASSESSMENT; SKIN; T-LYMPHOCYTES; TOXICITY TESTS; TOXICOLOGY;

EID: 84888294580     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.10.013     Document Type: Article

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