Molecular size as the main determinant of solute maximum flux across the skin

Journal of Investigative Dermatology

Volumn 122, Issue 4, 2004, Pages 993-999

  Magnusson, Beatrice M ^a   Anissimov, Yuri G ^a   Cross, Sheree E ^a   Roberts, Michael S ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Maximum flux; Prediction; Structure activity relationship; Transdermal penetration

Indexed keywords

OCTANOL;

ADDITION REACTION; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; EXPERIMENTAL TEST; HUMAN; HUMAN TISSUE; HYDROGEN BOND; ION TRANSPORT; IONIZATION; LITERATURE; MELTING POINT; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOLECULAR MODEL; MOLECULAR WEIGHT; PARAMETER; PARTICLE SIZE; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; REGRESSION ANALYSIS; SKIN PERMEABILITY; SOLUBILITY; SOLUTE;

EID: 2342599148     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.22413.x     Document Type: Article

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