Relevance of signaling molecules for apoptosis induction on influenza A virus replication

Biochemical and Biophysical Research Communications

Volumn 441, Issue 3, 2013, Pages 531-537

  Iwai, Atsushi ^a   Shiozaki, Takuya ^b   Miyazaki, Tadaaki ^b  

^a Aureo Science Co Ltd   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Influenza A virus; Signal transduction

Indexed keywords

CASPASE 3; DEATH RECEPTOR; INTERFERON REGULATORY FACTOR 3; RETINOIC ACID INDUCIBLE PROTEIN I; VIRUS PROTEIN;

APOPTOSIS; DISEASE SEVERITY; IMMUNE RESPONSE; INFLUENZA A; INFLUENZA VIRUS A; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; VIRUS REPLICATION; VIRUS VIRULENCE;

INFLUENZA A VIRUS; MAMMALIA;

AKT; APAF-1; APOPTOSIS; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; B-CELL LYMPHOMA 2; BAX; BCL-2; BCL-2 HOMOLOGY; BCL-2-ASSOCIATED X PROTEIN; BH; C-JUN AMINO-TERMINAL KINASE; CASPASES; CYSTEINE-ASPARTIC ACID PROTEASE; DAP3; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DEATH-ASSOCIATED PROTEIN 3; DR4; DR5; FADD; FAS-ASSOCIATED DEATH DOMAIN; IAV; IFN; IFN REGULATORY FACTOR 3; INF-Β PROMOTER STIMULATOR PROTEIN 1; INFLUENZA A VIRUS; INTERFERON; IPS-1; IRF3; JNK; M; MATRIX PROTEIN; NA; NEURAMINIDASE; NF-ΚB; NON-STRUCTURAL PROTEIN 1; NP; NS1; NUCLEAR FACTOR-ΚB; NUCLEOPROTEIN; PHOSPHATIDYLINOSITOL-3 KINASE; PI3K; RETINOIC ACID-INDUCIBLE GENE-I; RIG-I; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS INDUCING LIGAND; TNF-Α; TNF-Α RECEPTOR 1; TNFΑR1; TRADD; TRAIL; TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR Α; V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 1; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN; XIAP; ZAPS; ZINC FINGER ANTIVIRAL PROTEIN, SHORT FORM;

APOPTOSIS; CASPASE 3; DEAD-BOX RNA HELICASES; HUMANS; INFLUENZA A VIRUS; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84888294378     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.100     Document Type: Short Survey

References (45)

1. Hinshaw V.S., Olsen C.W., Dybdahl-Sissoko N., Evans D. Apoptosis: a mechanism of cell killing by influenza A and B viruses. J. Virol. 1994, 68:3667-3673.
2. Chan P.K. Outbreak of avian influenza A(H5N1) virus infection in Hong Kong in 1997. Clin. Infect. Dis. 2002, 34(Suppl. 2):S58-S64.
3. Alnemri E.S., Livingston D.J., Nicholson D.W., Salvesen G., Thornberry N.A., Wong W.W., Yuan J. Human ICE/CED-3 protease nomenclature. Cell 1996, 87:171.
4. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995, 376:37-43.
5. Enari M., Sakahira H., Yokoyama H., Okawa K., Iwamatsu A., Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998, 391:43-50.
6. Chinnaiyan A.M., O'Rourke K., Tewari M., Dixit V.M. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995, 81:505-512.
7. Hsu H., Xiong J., Goeddel D.V. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 1995, 81:495-504.
8. Miyazaki T., Reed J.C. A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins. Nat. Immunol. 2001, 2:493-500.
9. Zou H., Henzel W.J., Liu X., Lutschg A., Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997, 90:405-413.
10. Cory S., Adams J.M. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2002, 2:647-656.
11. Wurzer W.J., Planz O., Ehrhardt C., Giner M., Silberzahn T., Pleschka S., Ludwig S. Caspase 3 activation is essential for efficient influenza virus propagation. EMBO J. 2003, 22:2717-2728.
12. Hale B.G., Jackson D., Chen Y.H., Lamb R.A., Randall R.E. Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. Proc. Natl. Acad. Sci. USA 2006, 103:14194-14199.
13. Matsuda M., Suizu F., Hirata N., Miyazaki T., Obuse C., Noguchi M. Characterization of the interaction of influenza virus NS1 with Akt. Biochem. Biophys. Res. Commun. 2010, 395:312-317.
14. Gaur P., Ranjan P., Sharma S., Patel J.R., Bowzard J.B., Rahman S.K., Kumari R., Gangappa S., Katz J.M., Cox N.J., Lal R.B., Sambhara S., Lal S.K. Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein. J. Biol. Chem. 2012, 287:15109-15117.
15. Wurzer W.J., Ehrhardt C., Pleschka S., Berberich-Siebelt F., Wolff T., Walczak H., Planz O., Ludwig S. NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation. J. Biol. Chem. 2004, 279:30931-30937.
16. Ludwig S., Ehrhardt C., Neumeier E.R., Kracht M., Rapp U.R., Pleschka S. Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway. J. Biol. Chem. 2001, 276:10990-10998.
17. Ludwig S., Wang X., Ehrhardt C., Zheng H., Donelan N., Planz O., Pleschka S., Garcia-Sastre A., Heins G., Wolff T. The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors. J. Virol. 2002, 76:11166-11171.
18. Nacken W., Ehrhardt C., Ludwig S. Small molecule inhibitors of the c-Jun N-terminal kinase (JNK) possess antiviral activity against highly pathogenic avian and human pandemic influenza A viruses. Biol. Chem. 2012, 393:525-534.
19. Mehrotra S., Chhabra A., Hegde U., Chakraborty N.G., Mukherji B. Inhibition of c-Jun N-terminal kinase rescues influenza epitope-specific human cytolytic T lymphocytes from activation-induced cell death. J. Leukoc. Biol. 2007, 81:539-547.
20. Kawai T., Takahashi K., Sato S., Coban C., Kumar H., Kato H., Ishii K.J., Takeuchi O., Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 2005, 6:981-988.
21. Besch R., Poeck H., Hohenauer T., Senft D., Hacker G., Berking C., Hornung V., Endres S., Ruzicka T., Rothenfusser S., Hartmann G. Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells. J. Clin. Invest. 2009, 119:2399-2411.
22. Chattopadhyay S., Marques J.T., Yamashita M., Peters K.L., Smith K., Desai A., Williams B.R., Sen G.C. Viral apoptosis is induced by IRF-3-mediated activation of Bax. Embo J 2010, 29:1762-1773.
23. Lei Y., Moore C.B., Liesman R.M., O'Connor B.P., Bergstralh D.T., Chen Z.J., Pickles R.J., Ting J.P. MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS One 2009, 4:e5466.
24. Cardenas W.B., Loo Y.M., Gale M., Hartman A.L., Kimberlin C.R., Martinez-Sobrido L., Saphire E.O., Basler C.F. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. J. Virol. 2006, 80:5168-5178.
25. Pichlmair A., Schulz O., Tan C.P., Naslund T.I., Liljestrom P., Weber F., Reis e Sousa C. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006, 314:997-1001.
26. Gack M.U., Albrecht R.A., Urano T., Inn K.S., Huang I.C., Carnero E., Farzan M., Inoue S., Jung J.U., Garcia-Sastre A. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe 2009, 5:439-449.
27. Iwai A., Shiozaki T., Kawai T., Akira S., Kawaoka Y., Takada A., Kida H., Miyazaki T. Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1. J. Biol. Chem. 2010, 285:32064-32074.
28. Varga Z.T., Grant A., Manicassamy B., Palese P. Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential. J. Virol. 2012, 86:8359-8366.
29. Bradel-Tretheway B.G., Mattiacio J.L., Krasnoselsky A., Stevenson C., Purdy D., Dewhurst S., Katze M.G. Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors. J. Virol. 2011, 85:8569-8581.
30. Hayakawa S., Shiratori S., Yamato H., Kameyama T., Kitatsuji C., Kashigi F., Goto S., Kameoka S., Fujikura D., Yamada T., Mizutani T., Kazumata M., Sato M., Tanaka J., Asaka M., Ohba Y., Miyazaki T., Imamura M., Takaoka A. ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses. Nat. Immunol. 2011, 12:37-44.
31. Nencioni L., Iuvara A., Aquilano K., Ciriolo M.R., Cozzolino F., Rotilio G., Garaci E., Palamara A.T. Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2. FASEB J. 2003, 17:758-760.
32. Shiozaki T., Iwai A., Kawaoka Y., Takada A., Kida H., Miyazaki T. Requirement for Siva-1 for replication of influenza A virus through apoptosis induction. J. Gen. Virol. 2011, 92:315-325.
33. Resch U., Schichl Y.M., Winsauer G., Gudi R., Prasad K., de Martin R. Siva1 is a XIAP-interacting protein that balances NFkappaB and JNK signalling to promote apoptosis. J. Cell Sci. 2009, 122:2651-2661.
34. Deveraux Q.L., Takahashi R., Salvesen G.S., Reed J.C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997, 388:300-304.
35. Lad S.P., Yang G., Scott D.A., Chao T.H., Correia Jda S., de la Torre J.C., Li E. Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Mol. Immunol. 2008, 45:2277-2287.
36. Michallet M.C., Meylan E., Ermolaeva M.A., Vazquez J., Rebsamen M., Curran J., Poeck H., Bscheider M., Hartmann G., Konig M., Kalinke U., Pasparakis M., Tschopp J. TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity 2008, 28:651-661.
37. Li H.M., Fujikura D., Harada T., Uehara J., Kawai T., Akira S., Reed J.C., Iwai A., Miyazaki T. IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation. Cell Death Differ. 2009, 16:1615-1621.
38. Miyazaki T., Shen M., Fujikura D., Tosa N., Kim H.R., Kon S., Uede T., Reed J.C. Functional role of death-associated protein 3 (DAP3) in anoikis. J. Biol. Chem. 2004, 279:44667-44672.
39. Kissil J.L., Cohen O., Raveh T., Kimchi A. Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death. EMBO J. 1999, 18:353-362.
40. Takeda S., Iwai A., Nakashima M., Fujikura D., Chiba S., Li H.M., Uehara J., Kawaguchi S., Kaya M., Nagoya S., Wada T., Yuan J., Rayter S., Ashworth A., Reed J.C., Yamashita T., Uede T., Miyazaki T. LKB1 is crucial for TRAIL-mediated apoptosis induction in osteosarcoma. Anticancer Res. 2007, 27:761-768.
41. Harada T., Iwai A., Miyazaki T. Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction. Apoptosis 2010, 15:1247-1255.
42. Halder U.C., Bagchi P., Chattopadhyay S., Dutta D., Chawla-Sarkar M. Cell death regulation during influenza A virus infection by matrix (M1) protein: a model of viral control over the cellular survival pathway. Cell Death Dis. 2011, 2:e197.
43. Gannage M., Dormann D., Albrecht R., Dengjel J., Torossi T., Ramer P.C., Lee M., Strowig T., Arrey F., Conenello G., Pypaert M., Andersen J., Garcia-Sastre A., Munz C. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 2009, 6:367-380.
44. Chanturiya A.N., Basanez G., Schubert U., Henklein P., Yewdell J.W., Zimmerberg J. PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes. J. Virol. 2004, 78:6304-6312.
45. Tripathi S., Batra J., Cao W., Sharma K., Patel J.R., Ranjan P., Kumar A., Katz J.M., Cox N.J., Lal R.B., Sambhara S., Lal S.K. Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin. Cell Death Dis. 2013, 4:e562.