Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein

Journal of Biological Chemistry

Volumn 287, Issue 18, 2012, Pages 15109-15117

  Gaur, Pratibha ^a   Ranjan, Priya ^b   Sharma, Shipra ^a   Patel, Jenish R ^b   Bowzard, J Bradford ^b   Rahman, Shah K ^a   Kumari, Rashmi ^a   Gangappa, Shivaprakash ^b   Katz, Jacqueline M ^b   Cox, Nancy J ^b   Lal, Renu B ^b   Sambhara, Suryaprakash ^b   Lal, Sunil K ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULES; CELL SURVIVAL; HOST CELLS; HUMAN BRONCHIAL EPITHELIAL CELLS; HUMAN LUNG; INFECTED CELLS; INFLUENZA A VIRUS; INFLUENZA VIRUS; NEURAMINIDASE; VIRAL PROTEINS; VIRAL REPLICATION;

ANTIGENS; BIOMOLECULES; CELL DEATH; PHOSPHORYLATION; VIRUSES;

PROTEINS;

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; FOCAL ADHESION KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN BCL 2; PROTEIN KINASE B; SMALL INTERFERING RNA; STEROID RECEPTOR COACTIVATOR 1; VIRUS SIALIDASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CLUSTER ANALYSIS; CONTROLLED STUDY; DOWN REGULATION; INFLUENZA VIRUS A; LUNG ADENOCARCINOMA; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; VIRION; VIRUS CELL INTERACTION; VIRUS REPLICATION;

ANTIGENS, CD; APOPTOSIS; BRONCHI; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; EPITHELIAL CELLS; GLYCOGEN SYNTHASE KINASE 3; GPI-LINKED PROTEINS; HEK293 CELLS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; NEURAMINIDASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; VIRAL PROTEINS; VIRUS REPLICATION;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 84860374380     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.328070     Document Type: Article

References (35)

1. Taubenberger, J. K., and Morens, D. M. (2008) The pathology of influenza virus infections. Annu. Rev. Pathol. 3, 499-522 (Pubitemid 351488291)
2. Bouvier, N. M., and Palese, P. (2008) The biology of influenza viruses. Vaccine 26, D49-53
3. Ehrhardt, C., Wolff, T., Pleschka, S., Planz, O., Beermann, W., Bode, J. G., Schmolke, M., and Ludwig, S. (2007) Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses. J. Virol. 81, 3058-3067 (Pubitemid 46456615)
4. Hale, B. G., and Randall, R. E. (2007) PI3K signalling during influenza A virus infections. Biochem. Soc. Trans. 35, 186-187 (Pubitemid 46596464)
5. Shin, Y. K., Liu, Q., Tikoo, S. K., Babiuk, L. A., and Zhou, Y. (2007) Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation. J. Gen. Virol. 88, 942-950 (Pubitemid 46359565)
6. Flory, E., Kunz, M., Scheller, C., Jassoy, C., Stauber, R., Rapp, U. R., and Ludwig, S. (2000) Influenza virus-induced NF-κB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IκB kinase. J. Biol. Chem. 275, 8307-8314 (Pubitemid 30180170)
7. Arora, D. J., and Gasse, N. (1998) Influenza virus hemagglutinin stimulates the protein kinase C activity of human polymorphonuclear leucocytes. Arch. Virol. 143, 2029-2037 (Pubitemid 28537103)
8. Pahl, H. L., and Baeuerle, P. A. (1995) Expression of influenza virus hemagglutinin activates transcription factor NF-κB. J. Virol. 69, 1480-1484
9. Chazal, N., and Gerlier, D. (2003) Virus entry, assembly, budding, and membrane rafts. Microbiol. Mol. Biol. Rev. 67, 226-237, table of contents (Pubitemid 36693473)
10. Schultz-Cherry, S., and Hinshaw, V. S. (1996) Influenza virus neuraminidase activates latent transforming growth factor-β. J. Virol. 70, 8624-8629 (Pubitemid 26378442)
11. Miller, J. L., and Anders, E. M. (2003) Virus-cell interactions in the induction of type 1 interferon by influenza virus in mouse spleen cells. J. Gen. Virol. 84, 193-202 (Pubitemid 36113565)
12. Houde, M., and Arora, D. J. (1990) Stimulation of tumor necrosis factor secretion by purified influenza virus neuraminidase. Cell. Immunol. 129, 104-111 (Pubitemid 20233617)
13. Duxbury, M. S., Ito, H., Zinner, M. J., Ashley, S. W., and Whang, E. E. (2004) CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells. Oncogene 23, 465-473 (Pubitemid 38175001)
14. Duxbury, M. S., Ito, H., Ashley, S. W., and Whang, E. E. (2004) CEACAM6 cross-linking induces caveolin-1-dependent, Src-mediated focal adhesion kinase phosphorylation in BxPC3 pancreatic adenocarcinoma cells. J. Biol. Chem. 279, 23176-23182 (Pubitemid 38685623)
15. Kumar, P., Gunalan, V., Liu, B., Chow, V. T., Druce, J., Birch, C., Catton, M., Fielding, B. C., Tan, Y. J., and Lal, S. K. (2007) The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein. Virology 366, 293-303 (Pubitemid 47398912)
16. Ratra, R., Kar-Roy, A., and Lal, S. K. (2009) ORF3 protein of hepatitis E virus interacts with the β chain of fibrinogen resulting in decreased fibrinogen secretion from HuH-7 cells. J. Gen. Virol. 90, 1359-1370
17. Duxbury, M. S., Ito, H., Benoit, E., Waseem, T., Ashley, S. W., and Whang, E. E. (2004) A novel role for carcinoembryonic antigen-related cell adhesion molecule 6 as a determinant of gemcitabine chemoresistance in pancreatic adenocarcinoma cells. Cancer Res. 64, 3987-3993 (Pubitemid 38697314)
18. Duxbury, M. S., Ito, H., Benoit, E., Zinner, M. J., Ashley, S. W., and Whang, E. E. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene 23, 5834-5842 (Pubitemid 39093029)
19. Bhatia, A., and Kast, R. E. (2007) How influenza's neuraminidase promotes virulence and creates localized lung mucosa immunodeficiency. Cell Mol. Biol. Lett. 12, 111-119 (Pubitemid 46786645)
20. Matrosovich, M. N., Matrosovich, T. Y., Gray, T., Roberts, N. A., and Klenk, H. D. (2004) Neuraminidase is important for the initiation of influenza virus infection in human airway epithelium. J. Virol. 78, 12665-12667 (Pubitemid 39458784)
21. Gaur, P., Munjhal, A., and Lal, S. K. (2011) Influenza virus and cell signaling pathways. Med. Sci. Monit. 17, RA148-154
22. Shih, W. L., Kuo, M. L., Chuang, S. E., Cheng, A. L., and Doong, S. L. (2003) Hepatitis B virus X protein activates a survival signaling by linking SRC to phosphatidylinositol 3-kinase. J. Biol. Chem. 278, 31807-31813
23. Cooray, S. (2004) The pivotal role of phosphatidylinositol 3-kinase/Akt signal transduction in virus survival. J. Gen. Virol. 85, 1065-1076
24. Mannová, P., and Beretta, L. (2005) Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication. J. Virol. 79, 8742-8749 (Pubitemid 40934785)
25. Mizutani, T., Fukushi, S., Saijo, M., Kurane, I., and Morikawa, S. (2004) Importance of Akt signaling pathway for apoptosis in SARS-CoV-infected Vero E6 cells. Virology 327, 169-174 (Pubitemid 39209322)
26. Autret, A., Martin-Latil, S., Brisac, C., Mousson, L., Colbère-Garapin, F., and Blondel, B. (2008) Early phosphatidylinositol 3-kinase/Akt pathway activation limits poliovirus-induced JNK-mediated cell death. J. Virol. 82, 3796-3802 (Pubitemid 351429955)
27. Lee, C. J., Liao, C. L., and Lin, Y. L. (2005) Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. J. Virol. 79, 8388-8399
28. Hartshorn, K. L., and White, M. R. (1999) Influenza A virus up-regulates neutrophil adhesion molecules and adhesion to biological surfaces. J. Leukoc. Biol. 65, 614-622 (Pubitemid 29227052)
29. Kuespert, K., Pils, S., and Hauck, C. R. (2006) CEACAMs: their role in physiology and pathophysiology. Curr. Opin. Cell Biol. 18, 565-571 (Pubitemid 44332912)
30. Kasahara, K., Watanabe, K., Kozutsumi, Y., Oohira, A., Yamamoto, T., and Sanai, Y. (2002) Association of GPI-anchored protein TAG-1 with srcfamily kinase Lyn in lipid rafts of cerebellar granule cells. Neurochem. Res. 27, 823-829
31. Kirshner, J., Chen, C. J., Liu, P., Huang, J., and Shively, J. E. (2003) CEACAM1-4S, a cell-cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture. Proc. Natl. Acad. Sci. U.S.A. 100, 521-526 (Pubitemid 36126084)
32. Najjar, S. M. (2002) Regulation of insulin action by CEACAM1. Trends Endocrinol. Metab. 13, 240-245
33. Bouchard, V., Demers, M. J., Thibodeau, S., Laquerre, V., Fujita, N., Tsuruo, T., Beaulieu, J. F., Gauthier, R., Vézina, A., Villeneuve, L., and Vachon, P. H. (2007) Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways. J. Cell Physiol. 212, 717-728 (Pubitemid 47271883)
34. Ducker, T. P., and Skubitz, K. M. (1992) Subcellular localization of CD66, CD67, and NCA in human neutrophils. J. Leukoc. Biol. 52, 11-16
35. Han, S. U., Kwak, T. H., Her, K. H., Cho, Y. H., Choi, C., Lee, H. J., Hong, S., Park, Y. S., Kim, Y. S., Kim, T. A., Kim, S. J. (2008) CEACAM5 and CEACAM6 are major target genes for Smad3-mediated TGF-β signaling. Oncogene 27, 675-683 (Pubitemid 351158896)