Completely humanizing prolactin rescues infertility in prolactin knockout mice and leads to human prolactin expression in extrapituitary mouse tissues

Endocrinology

Volumn 154, Issue 12, 2013, Pages 4777-4789

  Christensen, Heather R ^a,b   Murawsky, Michael K ^a   Horseman, Nelson D ^a   Willson, Tara A ^a   Gregerson, Karen A ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b College of Mount St Joseph ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE MESILATE; ESTRADIOL; PROLACTIN; PROLACTIN ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; HORMONAL REGULATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFERTILITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROMOTER REGION; REPRODUCTION; TRANSGENE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; FEMALE INFERTILITY; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HYPOPHYSIS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; INFERTILITY, FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PITUITARY GLAND; PROLACTIN; RNA, MESSENGER;

EID: 84888270779     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1476     Document Type: Article

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