Null mutation of the prolactin receptor gene produces a defect in maternal behavior

Endocrinology

Volumn 139, Issue 10, 1998, Pages 4102-4107

  Lucas, B K ^a   Ormandy, C J ^b   Binart, N ^a   Bridges, R S ^c   Kelly, P A ^a  

^a INSERM   (France)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE; ESTRADIOL; PROLACTIN; PROLACTIN RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANOSMIA; ARTICLE; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; HOMOZYGOSITY; HYPOTHALAMUS; LEARNING; LOCOMOTION; MAMMAL; MATERNAL BEHAVIOR; MAZE TEST; NONHUMAN; OVARIECTOMY; PREOPTIC AREA; PRIORITY JOURNAL; RODENT; SEXUAL BEHAVIOR;

EID: 0031733935     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.10.6243     Document Type: Article

References (45)

1. Rosenblatt JS 1967 Nonhormonal basis of maternal behavior in the rat. Science 156:1512-1514
2. Cosnier J, Couturier C 1966 Comportement maternel induit chez les rattes adultes castrées. C R Seances Soc Biol Fil 160:789-791
3. Herrenkohl LR, Rosenberg PA 1972 Exteroceptive stimulation of maternal behavior in the naive rat. Physiol Behav 8:595-598
4. Fleming AS, Rosenblatt JS 1974 Olfactory regulation of maternal behavior in rats: effects of olfactory bulb removal in experienced and inexperienced lactating and cycling females. J Comp Physiol Psychol 86:221-232
5. Fleming AS, Gavarth K, Sarker J 1992 Effects of transections to the vomeronasal nerves or to the main olfactory bulbs on the initiation and long term retention of maternal behavior in primiparous rats. Behav Neural Biol 57:177-188
6. Mayer AD, Rosenblatt JS 1975 Olfactory basis for the delayed onset of maternal behavior in virgin female rats: experiential effects. J Comp Physiol Psychol 89:701-710
7. Bridges RS, Numan M, Rosheim PM, Mann PE, Lupini CE 1990 Central prolactin infusions stimulate maternal behavior in steroid-treated nulliparous female rats. Proc Natl Acad Sci 87:8003-8007
8. Bridges RS, Dibiase R, Loundes DD, Doherty PC 1984 Prolactin stimulation of maternal behavior in female rats. Science 227:782-784
9. Bazan JP 1989 A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor B chain. Biochem Biophys Res Commun 164:788-795
10. Bakowska JC, Morrell JI 1998 Atlas of the neurons that express mRNA for the long form of the prolactin receptor in the forebrain of the female rat. J Comp Neurol 386:161-177
11. Shamgochian MD, Avakian C, Truond NH, Stone S, Tang KT, DeVito WJ 1995 Regulation of prolactin receptor expression by estradiol in the female Tat brain. Neuroreport 6:2537-2541
12. Buntin JD 1993 Prolactin-brain interactions and reproductive function. Am Zool 33:229-243
13. Voci VE, Carlson NR 1973 Enhancement of maternal behavior and nest building following systemic and diencephalic administration of prolactin and progesterone in the mouse. J Comp Physiol Psychol 88:388-393
14. Bridges RS, Ronsheim PM 1990 Prolactin (PRL) regulation of maternal behavior in rats: bromocriptine treatment delays and PRL promotes the rapid onset of behavior. Endocrinology 126:837-848
15. Bridges RS, Dunckel PT 1987 Hormonal regulation of maternal behavior in rats: stimulation following treatment with ectopic pituitary grafts plus progesterone. Biol Reprod 37:518-526
16. Bridges RS 1994 The role of lactogenic hormones in maternal behavior in female rats. Acta Paediatr 397:33-39
17. Ormandy CJ, Camus A, Barra J, Damotte D, Lucas BK, Buteau H, Edery M, Brousse N, Babinet C, Binart N, Kelly PA 1997 Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev 11:167-178
18. Abeliovich A, Paylor R, Chen C, Jeansok JK, Wehner JM, Tonegawa S 1993 PKC-mutant mice exhibit mild defects in spatial and contextual learning. Cell 75:1263-1271
19. Darling FMC, Slotnick BM 1994 Odor-cued taste avoidance: a simple and efficient method for assessing olfactory detection, discrimination and memory in the rat. Physiol Behav 55:817-822
20. Neville MC, Daniel CW 1987 The Mammary Gland. Development, Regulation and Function. Plenum Press, New York
21. Morishige WK, Pepe GJ, Rothchild I 1973 Serum luteinizing hormone, prolactin and progesterone levels during pregnancy in the rat. Endocrinology 92:1527-1530
22. Loundes DD, Bridges RS 1986 Length of prolactin priming differentially affects maternal behavior in female rats. Biol Reprod 34:495-501
23. Rosenblatt JS, Siegel HI, Mayer AD 1979 Progress in the study of maternal behavior in the rat: hormonal, nonhormonal, sensory, and developmental aspects. In: Rosenblatt JS, Hinde RA (eds) Advances in the Study of Behavior. Academic Press, New York, 10:226-302
24. Koch M, Ehret G 1989 Estradiol and parental influence, but not prolactin are necessary for ultrasound recognition and pup retrieving in the mouse. Physiol Behav 45:771-776
25. Bridges RS, Millard WJ 1988 Growth hormone is secreted by ectopic pituitary grafts and stimulates maternal behavior in rats. Horm Behav 22:194-206
26. Bridges RS, Robertson MC, Shiu RPC, Friesen HG, Stuer AM, Mann PE 1996 Endocrine communication between conceptus and mother: placental lactogen stimulation of maternal behavior. Neuroendocrinology 64:57-64
27. Stanley BG, Leibowitz SF 1985 Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior. Proc Natl Acad Sci USA 82:3940-3943
28. Edwards DA, Walter B, Liang P 1996 Hypothalamic and olfactory control of sexual behavior and partner preference in male rats. Physiol Behav 60:1347-1354
29. Berdashkevich AP 1975 Hypothalamic autostimulation in rats at low frequencies of stimulation on the basis of locomotion. Biull Eksp Biol Med 79:6-9
30. Numan M, Corodimas KP, Numan MJ, Factor EM, Piers WD 1988 Axonsparing lesions of the preoptic region and substantia innominata disrupt maternal behavior in rats. Behav Neurosci 102:381-396
31. Sugiyama T, Minoura H, Toyoda N, Sakaguchi K, Tanaka M, Sudo S, Nakashima K 1996 Pup contact induces the expression of long form prolactin receptor mRNA in the brain of female rats: effects of ovariectomy and hypophysectomy on the receptor gene expression. J Endocrinol 161:324-329
32. Gandelman R, Zarrow MX, Denenberg VH, Myers M 1971 Olfactory bulb removal eliminates maternal behavior in the mouse. Science 171:210-211
33. Freemark M, Driscoll P, Andrews J, Kelly PA, Royster M 1996 Ontogenesis of prolactin receptor gene expression in the rat olfactory system: potential roles for lactogenic hormones in olfactory development. Endocrinology 137:934-942
34. Schanzel-Fakuda M, Jorganson KL, Bergen HT, Weesner G D, Pfaff DW 1992 Biology of normal luteinizing hormone releasing hormone neurons during and after their migration from olfactory placode. Endocr Rev 13:623-634
35. Fleming AS, Vaccarino F, Luebke C 1980 Amygdaloid inhibition of maternal behavior in the nulliparous female rat. Physiol Behav 25:731-743
36. Morris RGM 3981 Spatial localization does not require the presence of local cues. Learn Motiv 12:239-260
37. Eichenbaum H, Otto T, Cohen NJ 1992 The hippocampus: what does it do? Behav Neural Biol 57:2-36
38. Bouchon R, Ropartz P 1994 Pituitary grafts and behavior in mice. Effects of sex of donor and number of pituitary grafts on exploratory and learning abilities. Physiol Behav 55:711-715
39. Mayer AD, Rosenblatt JS 1977 Effects of intranasal zinc on open field and maternal behavior in female rats. Physiol Behav 18:101-109
40. Mayer AD, Rosenblatt JS 1979 Hormonal influences during ontogeny of maternal behavior in female rats. J Comp Physiol Psychol 93:879-898
41. Fleming AS, Luebke C 1981 Timidity prevents the virgin female rat from being a good mother: emotionality differences between nulliparous and parturient females. Physiol Behav 27:863-868
42. Hansen S, Ferreira A, Selart ME 1995 Behavioral similarities between mother rats and benzodiazepine-treated nonmaternal animals. Psychopharmacology 86:344-347
43. Hard E, Hansen S 1985 Reducing fearfulness in the lactating rat. Physiol Behav 35:641-643
44. Qureshi GA, Hansen S, Sodersten P 1987 Offspring control of cerebrospinal fluid GABA concentrations in lactating rats. Neurosci Lett 75:85-88
45. Hansen S 1990 Mechanisms involved in the control of punished responding in mother rats. Horm Behav 24:186-197