-
1
-
-
0036790977
-
Diversity, topographic differentiation, and positional memory in human fibroblasts
-
Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, et al. Diversity, topographic differentiation, and positional memory in human fibroblasts. Proc Natl Acad Sci U S A 2002;99:12877-82.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12877-12882
-
-
Chang, H.Y.1
Chi, J.T.2
Dudoit, S.3
Bondre, C.4
Van De Rijn, M.5
Botstein, D.6
-
2
-
-
0036277026
-
Myofibroblasts and mechano-regulation of connective tissue remodelling
-
Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 2002;3:349-63.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 349-363
-
-
Tomasek, J.J.1
Gabbiani, G.2
Hinz, B.3
Chaponnier, C.4
Brown, R.A.5
-
3
-
-
0014545123
-
Ultrastructural features of wound healing in mouse skin
-
Tarin D, Croft CB. Ultrastructural features of wound healing in mouse skin. J Anat 1969;105:189-90.
-
(1969)
J Anat
, vol.105
, pp. 189-190
-
-
Tarin, D.1
Croft, C.B.2
-
5
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-7.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
6
-
-
8144228952
-
Friends or foes-bipolar effects of the tumour stroma in cancer
-
Mueller MM, Fusenig NE. Friends or foes-bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 2004;4:839-49.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
7
-
-
0023939143
-
Smoothmuscle differentiation in stromal cells of malignant and non-malignant breast tissues
-
Sappino AP, Skalli O, Jackson B, Schurch W, Gabbiani G. Smoothmuscle differentiation in stromal cells of malignant and non-malignant breast tissues. Int J Cancer 1988;41:707-12.
-
(1988)
Int J Cancer
, vol.41
, pp. 707-712
-
-
Sappino, A.P.1
Skalli, O.2
Jackson, B.3
Schurch, W.4
Gabbiani, G.5
-
8
-
-
0033178473
-
Mechanisms of myofibroblast activity and phenotypic modulation
-
Serini G, Gabbiani G. Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 1999;250:273-83.
-
(1999)
Exp Cell Res
, vol.250
, pp. 273-283
-
-
Serini, G.1
Gabbiani, G.2
-
9
-
-
76349096670
-
Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumorpromoting inflammation in an NF-kappaB-dependent manner
-
Erez N, Truitt M, Olson P, Arron ST, Hanahan D. Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumorpromoting inflammation in an NF-kappaB-dependent manner. Cancer Cell 2010;17:135-47.
-
(2010)
Cancer Cell
, vol.17
, pp. 135-147
-
-
Erez, N.1
Truitt, M.2
Olson, P.3
Arron, S.T.4
Hanahan, D.5
-
10
-
-
38849141696
-
Cancer-associated stromal fibroblasts promote pancreatic tumor progression
-
Hwang RF, Moore T, Arumugam T, Ramachandran V, Amos KD, Rivera A, et al. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res 2008;68:918-26.
-
(2008)
Cancer Res
, vol.68
, pp. 918-926
-
-
Hwang, R.F.1
Moore, T.2
Arumugam, T.3
Ramachandran, V.4
Amos, K.D.5
Rivera, A.6
-
11
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999;59:5002-11.
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
Grossfeld, G.D.2
Hayward, S.W.3
Carroll, P.R.4
Tlsty, T.D.5
Cunha, G.R.6
-
12
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth andangiogenesis throughelevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth andangiogenesis throughelevated SDF-1/CXCL12 secretion. Cell 2005;121:335-48.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
-
13
-
-
33747859659
-
Stromal fibroblasts in cancer: A novel tumorpromoting cell type
-
Orimo A, Weinberg RA. Stromal fibroblasts in cancer: a novel tumorpromoting cell type. Cell Cycle 2006;5:1597-601.
-
(2006)
Cell Cycle
, vol.5
, pp. 1597-1601
-
-
Orimo, A.1
Weinberg, R.A.2
-
14
-
-
75849159205
-
Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression
-
Shimoda M, Mellody KT, Orimo A. Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression. Semin Cell Dev Biol 2010;21:19-25.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 19-25
-
-
Shimoda, M.1
Mellody, K.T.2
Orimo, A.3
-
15
-
-
0035890799
-
Malignant transformation in a nontumorigenic human prostatic epithelial cell line
-
Hayward SW, Wang Y, Cao M, Hom YK, Zhang B, Grossfeld GD, et al. Malignant transformation in a nontumorigenic human prostatic epithelial cell line. Cancer Res 2001;61:8135-42.
-
(2001)
Cancer Res
, vol.61
, pp. 8135-8142
-
-
Hayward, S.W.1
Wang, Y.2
Cao, M.3
Hom, Y.K.4
Zhang, B.5
Grossfeld, G.D.6
-
17
-
-
0035003342
-
Tumors are unique organs defined by abnormal signaling and context
-
Radisky D, Hagios C, Bissell MJ. Tumors are unique organs defined by abnormal signaling and context. Semin Cancer Biol 2001;11:87-95.
-
(2001)
Semin Cancer Biol
, vol.11
, pp. 87-95
-
-
Radisky, D.1
Hagios, C.2
Bissell, M.J.3
-
18
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty TD, Coussens LM. Tumor stroma and regulation of cancer development. Annu Rev Pathol 2006;1:119-50.
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
19
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
20
-
-
0026674919
-
Focal adhesion proteintyrosine kinase phosphorylated in response to cell attachment to fibronectin
-
Hanks SK, Calalb MB, Harper MC, Patel SK. Focal adhesion proteintyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc Natl Acad Sci U S A 1992;89:8487-91.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8487-8491
-
-
Hanks, S.K.1
Calalb, M.B.2
Harper, M.C.3
Patel, S.K.4
-
22
-
-
0027679403
-
Integrin cytoplasmic domains: Mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
-
Sastry SK, Horwitz AF. Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling. Curr Opin Cell Biol 1993;5:819-31.
-
(1993)
Curr Opin Cell Biol
, vol.5
, pp. 819-831
-
-
Sastry, S.K.1
Horwitz, A.F.2
-
23
-
-
0038823614
-
Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase
-
Thannickal VJ, Lee DY, White ES, Cui Z, Larios JM, Chacon R, et al. Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. J Biol Chem 2003;278:12384-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 12384-12389
-
-
Thannickal, V.J.1
Lee, D.Y.2
White, E.S.3
Cui, Z.4
Larios, J.M.5
Chacon, R.6
-
24
-
-
79952216583
-
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution
-
Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, et al. LOXL2-mediated matrix remodeling in metastasis and mammary gland involution. Cancer Res 2011;71:1561-72.
-
(2011)
Cancer Res
, vol.71
, pp. 1561-1572
-
-
Barker, H.E.1
Chang, J.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Nicolau, M.6
-
25
-
-
0026503190
-
Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
-
Aslakson CJ, Miller FR. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 1992;52:1399-405.
-
(1992)
Cancer Res
, vol.52
, pp. 1399-1405
-
-
Aslakson, C.J.1
Miller, F.R.2
-
26
-
-
79952327797
-
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer
-
Baker AM, Cox TR, Bird D, Lang G, Murray GI, Sun XF, et al. The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer. J Natl Cancer Inst 2011;103:407-24.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 407-424
-
-
Baker, A.M.1
Cox, T.R.2
Bird, D.3
Lang, G.4
Murray, G.I.5
Sun, X.F.6
-
27
-
-
84876119523
-
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
-
Baker AM, Bird D, Lang G, Cox TR, Erler JT. Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK. Oncogene 2013;32:1863-8.
-
(2013)
Oncogene
, vol.32
, pp. 1863-1868
-
-
Baker, A.M.1
Bird, D.2
Lang, G.3
Cox, T.R.4
Erler, J.T.5
-
28
-
-
57349153946
-
A small molecule inhibitor, 1, 2, 4, 5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth
-
Golubovskaya VM, Nyberg C, Zheng M, Kweh F, Magis A, Ostrov D, et al. A small molecule inhibitor, 1, 2, 4, 5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem 2008;51:7405-16.
-
(2008)
J Med Chem
, vol.51
, pp. 7405-7416
-
-
Golubovskaya, V.M.1
Nyberg, C.2
Zheng, M.3
Kweh, F.4
Magis, A.5
Ostrov, D.6
-
29
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicolau M, Dornhofer N, Kong C, Le QT, et al. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 2006;440:1222-6.
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
-
30
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, et al. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 2009;15:35-44.
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
-
31
-
-
0022501322
-
Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody
-
Van Vliet E, Melis M, Foidart JM, Van Ewijk W. Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody. J Histochem Cytochem 1986;34:883-90.
-
(1986)
J Histochem Cytochem
, vol.34
, pp. 883-890
-
-
Van Vliet, E.1
Melis, M.2
Foidart, J.M.3
Van Ewijk, W.4
-
32
-
-
79958250916
-
FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
-
Lee HO, Mullins SR, Franco-Barraza J, Valianou M, Cukierman E, Cheng JD. FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells. BMC Cancer 2011;11:245.
-
(2011)
BMC Cancer
, vol.11
, pp. 245
-
-
Lee, H.O.1
Mullins, S.R.2
Franco-Barraza, J.3
Valianou, M.4
Cukierman, E.5
Cheng, J.D.6
-
33
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 2009;139:891-906.
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
-
34
-
-
34447276000
-
Tumor microenvironment: The role of the tumor stroma in cancer
-
Li H, Fan X, Houghton J. Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biochem 2007;101:805-15.
-
(2007)
J Cell Biochem
, vol.101
, pp. 805-815
-
-
Li, H.1
Fan, X.2
Houghton, J.3
-
35
-
-
33846782878
-
Collagen reorganization at the tumor-stromal interface facilitates local invasion
-
Provenzano PP, Eliceiri KW, Campbell JM, Inman DR, White JG, Keely PJ. Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med 2006;4:38.
-
(2006)
BMC Med
, vol.4
, pp. 38
-
-
Provenzano, P.P.1
Eliceiri, K.W.2
Campbell, J.M.3
Inman, D.R.4
White, J.G.5
Keely, P.J.6
-
36
-
-
84864962631
-
The role of the myofibroblast in tumor stroma remodeling
-
Otranto M, Sarrazy V, Bonte F, Hinz B, Gabbiani G, Desmouliere A. The role of the myofibroblast in tumor stroma remodeling. Cell Adh Migr 2012;6:203-19.
-
(2012)
Cell Adh Migr
, vol.6
, pp. 203-219
-
-
Otranto, M.1
Sarrazy, V.2
Bonte, F.3
Hinz, B.4
Gabbiani, G.5
Desmouliere, A.6
-
37
-
-
0035159094
-
Alphasmooth muscle actin expression upregulates fibroblast contractile activity
-
Hinz B, Celetta G, Tomasek JJ, Gabbiani G, Chaponnier C. Alphasmooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell 2001;12:2730-41.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 2730-2741
-
-
Hinz, B.1
Celetta, G.2
Tomasek, J.J.3
Gabbiani, G.4
Chaponnier, C.5
-
38
-
-
0029149053
-
Factors influencing myofibroblast differentiation during wound healing and fibrosis
-
Desmouliere A. Factors influencing myofibroblast differentiation during wound healing and fibrosis. Cell Biol Int 1995;19:471-6.
-
(1995)
Cell Biol Int
, vol.19
, pp. 471-476
-
-
Desmouliere, A.1
-
39
-
-
0027212686
-
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
-
Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 1993;122:103-11.
-
(1993)
J Cell Biol
, vol.122
, pp. 103-111
-
-
Desmouliere, A.1
Geinoz, A.2
Gabbiani, F.3
Gabbiani, G.4
-
40
-
-
0242319836
-
Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation
-
Kolodsick JE, Peters-Golden M, Larios J, Toews GB, Thannickal VJ, Moore BB. Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation. Am J Respir Cell Mol Biol 2003;29:537-44.
-
(2003)
Am J Respir Cell Mol Biol
, vol.29
, pp. 537-544
-
-
Kolodsick, J.E.1
Peters-Golden, M.2
Larios, J.3
Toews, G.B.4
Thannickal, V.J.5
Moore, B.B.6
-
41
-
-
34447309766
-
The myofibroblast: One function, multiple origins
-
Hinz B, Phan SH, Thannickal VJ, Galli A, Bochaton-Piallat ML, Gabbiani G. The myofibroblast: one function, multiple origins. Am J Pathol 2007;170:1807-16.
-
(2007)
Am J Pathol
, vol.170
, pp. 1807-1816
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Galli, A.4
Bochaton-Piallat, M.L.5
Gabbiani, G.6
-
42
-
-
0037164867
-
The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis
-
Danen EH, Sonneveld P, Brakebusch C, Fassler R, Sonnenberg A. The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis. J Cell Biol 2002;159:1071-86.
-
(2002)
J Cell Biol
, vol.159
, pp. 1071-1086
-
-
Danen, E.H.1
Sonneveld, P.2
Brakebusch, C.3
Fassler, R.4
Sonnenberg, A.5
-
43
-
-
0035516140
-
Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk
-
Geiger B, Bershadsky A, Pankov R, Yamada KM. Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk. Nat Rev Mol Cell Biol 2001;2:793-805.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 793-805
-
-
Geiger, B.1
Bershadsky, A.2
Pankov, R.3
Yamada, K.M.4
-
44
-
-
0026612521
-
Pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
-
Schaller MD, Borgman CA, Cobb BS, Vines RR, Reynolds AB, Parsons JT. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci U S A 1992;89:5192-6.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cobb, B.S.3
Vines, R.R.4
Reynolds, A.B.5
Parsons, J.T.6
-
45
-
-
0027291705
-
Focal adhesion kinase: An integrin-linked protein tyrosine kinase
-
Schaller MD, Parsons JT. Focal adhesion kinase: an integrin-linked protein tyrosine kinase. Trends Cell Biol 1993;3:258-62.
-
(1993)
Trends Cell Biol
, vol.3
, pp. 258-262
-
-
Schaller, M.D.1
Parsons, J.T.2
-
46
-
-
0030888680
-
Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence
-
Saito H, Papaconstantinou J, Sato H, Goldstein S. Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence. J Biol Chem 1997;272:8157-60.
-
(1997)
J Biol Chem
, vol.272
, pp. 8157-8160
-
-
Saito, H.1
Papaconstantinou, J.2
Sato, H.3
Goldstein, S.4
-
47
-
-
38549116786
-
Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis
-
Dean JP, Nelson PS. Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis. Br J Cancer 2008;98:245-9.
-
(2008)
Br J Cancer
, vol.98
, pp. 245-249
-
-
Dean, J.P.1
Nelson, P.S.2
-
48
-
-
20144386127
-
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
-
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sorlie T, et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A 2005;102:3738-43.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3738-3743
-
-
Chang, H.Y.1
Nuyten, D.S.2
Sneddon, J.B.3
Hastie, T.4
Tibshirani, R.5
Sorlie, T.6
-
49
-
-
19344363035
-
Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
-
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, et al. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2004;2:E7.
-
(2004)
PLoS Biol
, vol.2
-
-
Chang, H.Y.1
Sneddon, J.B.2
Alizadeh, A.A.3
Sood, R.4
West, R.B.5
Montgomery, K.6
|