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Volumn 10, Issue 7, 2013, Pages 706-713

Distinct roles of sAPP-α and sAPP-β in regulating U251 cell differentiation

Author keywords

Alzheimer's disease; APP; Differentiation; Down syndrome; Glioma; Neural stem cells; sAPP ; sAPP ; U251

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN ALPHA; AMYLOID PRECURSOR PROTEIN BETA; UNCLASSIFIED DRUG;

EID: 84888265424     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/15672050113109990141     Document Type: Article
Times cited : (4)

References (38)
  • 1
    • 0033595706 scopus 로고    scopus 로고
    • Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286: 735-741 (1999).
    • (1999) Science , vol.286 , pp. 735-741
    • Vassar, R.1    Bennett, B.D.2    Babu-Khan, S.3    Kahn, S.4    Mendiaz, E.A.5    Denis, P.6
  • 3
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
    • Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736 (1987).
    • (1987) Nature , vol.325 , pp. 733-736
    • Kang, J.1    Lemaire, H.G.2    Unterbeck, A.3    Salbaum, J.M.4    Masters, C.L.5    Grzeschik, K.H.6
  • 4
    • 0034069795 scopus 로고    scopus 로고
    • Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides
    • Chen QS, Kagan BL, Hirakura Y, Xie CW. Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. J Neurosci Res 60: 65-72 (2000).
    • (2000) J Neurosci Res , vol.60 , pp. 65-72
    • Chen, Q.S.1    Kagan, B.L.2    Hirakura, Y.3    Xie, C.W.4
  • 5
    • 0031026779 scopus 로고    scopus 로고
    • Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping
    • Clarris HJ, Cappai R, Heffernan D, Beyreuther K, Masters CL, Small DH. Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping. J Neurochem 68: 1164-1172 (1997).
    • (1997) J Neurochem , vol.68 , pp. 1164-1172
    • Clarris, H.J.1    Cappai, R.2    Heffernan, D.3    Beyreuther, K.4    Masters, C.L.5    Small, D.H.6
  • 6
    • 80052266213 scopus 로고    scopus 로고
    • The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics
    • Karran E, Mercken M, De Strooper B. The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics. Nat Rev Drug Discov 10: 698-712 (2011).
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 698-712
    • Karran, E.1    Mercken, M.2    de Strooper, B.3
  • 7
    • 0024408853 scopus 로고
    • Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein
    • Palmert MR, Siedlak SL, Podlisny MB, Greenberg B, Shelton ER, Chan HW, et al. Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein. Biochem Biophys Res Commun 165: 182-188 (1989).
    • (1989) Biochem Biophys Res Commun , vol.165 , pp. 182-188
    • Palmert, M.R.1    Siedlak, S.L.2    Podlisny, M.B.3    Greenberg, B.4    Shelton, E.R.5    Chan, H.W.6
  • 9
  • 10
    • 0028982840 scopus 로고
    • Decreased alpha-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease
    • Lannfelt L, Basun H, Wahlund LO, Rowe BA, Wagner SL. Decreased alpha-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease. Nat Med 1: 829-832 (1995).
    • (1995) Nat Med , vol.1 , pp. 829-832
    • Lannfelt, L.1    Basun, H.2    Wahlund, L.O.3    Rowe, B.A.4    Wagner, S.L.5
  • 11
    • 0029841562 scopus 로고    scopus 로고
    • Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain
    • Furukawa K, Sopher BL, Rydel RE, Begley JG, Pham DG, Martin GM, et al. Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J Neurochem 67: 1882-1896 (1996).
    • (1996) J Neurochem , vol.67 , pp. 1882-1896
    • Furukawa, K.1    Sopher, B.L.2    Rydel, R.E.3    Begley, J.G.4    Pham, D.G.5    Martin, G.M.6
  • 12
    • 79952529991 scopus 로고    scopus 로고
    • What the halted phase III gamma-secretase inhibitor trial may (or may not) be telling us
    • Schor NF. What the halted phase III gamma-secretase inhibitor trial may (or may not) be telling us. Ann Neurol 69: 237-239 (2011).
    • (2011) Ann Neurol , vol.69 , pp. 237-239
    • Schor, N.F.1
  • 13
    • 72549105935 scopus 로고    scopus 로고
    • Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: A randomized controlled trial
    • Green RC, Schneider LS, Amato DA, Beelen AP, Wilcock G, Swabb EA, et al. Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. JAMA 302: 2557-64 (2009).
    • (2009) JAMA , vol.302 , pp. 2557-2564
    • Green, R.C.1    Schneider, L.S.2    Amato, D.A.3    Beelen, A.P.4    Wilcock, G.5    Swabb, E.A.6
  • 15
    • 84655162702 scopus 로고    scopus 로고
    • Developing beta-secretase inhibitors for treatment of Alzheimer's disease
    • Ghosh AK, Brindisi M, Tang J. Developing beta-secretase inhibitors for treatment of Alzheimer's disease. J Neurochem 120(1): 71-83 (2012).
    • (2012) J Neurochem , vol.120 , Issue.1 , pp. 71-83
    • Ghosh, A.K.1    Brindisi, M.2    Tang, J.3
  • 16
    • 84655160771 scopus 로고    scopus 로고
    • Activation of alpha-secretase cleavage
    • Postina R. Activation of alpha-secretase cleavage. J Neurochem 120(1): 46-54 (2012).
    • (2012) J Neurochem , vol.120 , Issue.1 , pp. 46-54
    • Postina, R.1
  • 17
    • 79955655453 scopus 로고    scopus 로고
    • Activation of the alpha-secretase processing of AbetaPP as a therapeutic approach in Alzheimer's disease
    • Vincent B, Govitrapong P. Activation of the alpha-secretase processing of AbetaPP as a therapeutic approach in Alzheimer's disease. J Alzheimers Dis 24(2): 75-94 (2011).
    • (2011) J Alzheimers Dis , vol.24 , Issue.2 , pp. 75-94
    • Vincent, B.1    Govitrapong, P.2
  • 18
    • 33746216955 scopus 로고    scopus 로고
    • Amyloid precursor protein regulates differentiation of human neural stem cells
    • Kwak YD, Brannen CL, Qu T, Kim HM, Dong X, Soba P, et al. Amyloid precursor protein regulates differentiation of human neural stem cells. Stem Cells Dev 15: 381-389 (2006).
    • (2006) Stem Cells Dev , vol.15 , pp. 381-389
    • Kwak, Y.D.1    Brannen, C.L.2    Qu, T.3    Kim, H.M.4    Dong, X.5    Soba, P.6
  • 19
    • 33645940285 scopus 로고    scopus 로고
    • sAPPalpha enhances the transdifferentiation of adult bone marrow progenitor cells to neuronal phenotypes
    • Chen CW, Boiteau RM, Lai WF, Barger SW, Cataldo AM. sAPPalpha enhances the transdifferentiation of adult bone marrow progenitor cells to neuronal phenotypes. Curr Alzheimer Res 3: 63-70 (2006).
    • (2006) Curr Alzheimer Res , vol.3 , pp. 63-70
    • Chen, C.W.1    Boiteau, R.M.2    Lai, W.F.3    Barger, S.W.4    Cataldo, A.M.5
  • 20
    • 67349257218 scopus 로고    scopus 로고
    • A novel approach to the identification and enrichment of cancer stem cells from a cultured human glioma cell line
    • Zhou ZH, Ping YF, Yu SC, Yi L, Yao XH, Chen JH, et al. A novel approach to the identification and enrichment of cancer stem cells from a cultured human glioma cell line. Cancer Lett 281: 92-99 (2009).
    • (2009) Cancer Lett , vol.281 , pp. 92-99
    • Zhou, Z.H.1    Ping, Y.F.2    Yu, S.C.3    Yi, L.4    Yao, X.H.5    Chen, J.H.6
  • 22
    • 0026767361 scopus 로고
    • Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage
    • Hung AY, Koo EH, Haass C, Selkoe DJ. Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage. Proc Natl Acad Sci U S A 89: 9439-9443 (1992).
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 9439-9443
    • Hung, A.Y.1    Koo, E.H.2    Haass, C.3    Selkoe, D.J.4
  • 23
    • 0028445312 scopus 로고
    • Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons
    • Salbaum JM, Ruddle FH. Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons. J Exp Zool 269: 116-127 (1994).
    • (1994) J Exp Zool , vol.269 , pp. 116-127
    • Salbaum, J.M.1    Ruddle, F.H.2
  • 24
    • 2542519087 scopus 로고    scopus 로고
    • Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone
    • Caille I, Allinquant B, Dupont E, Bouillot C, Langer A, Muller U, et al. Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone. Development 131: 2173-2181 (2004).
    • (2004) Development , vol.131 , pp. 2173-2181
    • Caille, I.1    Allinquant, B.2    Dupont, E.3    Bouillot, C.4    Langer, A.5    Muller, U.6
  • 25
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • Huang Y, Mucke L. Alzheimer mechanisms and therapeutic strategies. Cell 148: 1204-1222 (2012).
    • (2012) Cell , vol.148 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 26
    • 3343015515 scopus 로고    scopus 로고
    • Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress
    • Dong H, Goico B, Martin M, Csernansky CA, Bertchume A, Csernansky JG. Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress. Neuroscience 127: 601-609 (2004).
    • (2004) Neuroscience , vol.127 , pp. 601-609
    • Dong, H.1    Goico, B.2    Martin, M.3    Csernansky, C.A.4    Bertchume, A.5    Csernansky, J.G.6
  • 27
  • 28
    • 84055213663 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis and its role in Alzheimer's disease
    • Mu Y, Gage FH. Adult hippocampal neurogenesis and its role in Alzheimer's disease. Mol Neurodegener 6: 85 (2011).
    • (2011) Mol Neurodegener , vol.6 , pp. 85
    • Mu, Y.1    Gage, F.H.2
  • 29
    • 33847258237 scopus 로고    scopus 로고
    • Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease
    • Zhang C, McNeil E, Dressler L, Siman R. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Exp Neurol 204: 77-87 (2007).
    • (2007) Exp Neurol , vol.204 , pp. 77-87
    • Zhang, C.1    McNeil, E.2    Dressler, L.3    Siman, R.4
  • 30
    • 3042751874 scopus 로고    scopus 로고
    • The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice
    • Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, et al. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Exp Neurol 188: 224-237 (2004).
    • (2004) Exp Neurol , vol.188 , pp. 224-237
    • Wen, P.H.1    Hof, P.R.2    Chen, X.3    Gluck, K.4    Austin, G.5    Younkin, S.G.6
  • 31
    • 2942653014 scopus 로고    scopus 로고
    • Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis
    • Wang R, Dineley KT, Sweatt JD, Zheng H. Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis. Neuroscience126: 305-312 (2004).
    • (2004) Neuroscience , vol.126 , pp. 305-312
    • Wang, R.1    Dineley, K.T.2    Sweatt, J.D.3    Zheng, H.4
  • 32
    • 21244476031 scopus 로고    scopus 로고
    • Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation
    • Chevallier NL, Soriano S, Kang DE, Masliah E, Hu G, Koo EH. Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation. Am J Pathol 167: 151-159 (2005).
    • (2005) Am J Pathol , vol.167 , pp. 151-159
    • Chevallier, N.L.1    Soriano, S.2    Kang, D.E.3    Masliah, E.4    Hu, G.5    Koo, E.H.6
  • 33
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory?
    • Deng W, Aimone JB, Gage FH. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 11: 339-350 (2010).
    • (2010) Nat Rev Neurosci , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 34
    • 79956192109 scopus 로고    scopus 로고
    • Resolving new memories: A critical look at the dentate gyrus, adult neurogenesis, and pattern separation
    • Aimone JB, Deng W, Gage FH. Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation. Neuron 70: 589-596 (2011).
    • (2011) Neuron , vol.70 , pp. 589-596
    • Aimone, J.B.1    Deng, W.2    Gage, F.H.3
  • 36
    • 0037176537 scopus 로고    scopus 로고
    • Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: A gene expression study
    • Bahn S, Mimmack M, Ryan M, Caldwell MA, Jauniaux E, Starkey M, et al. Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. Lancet 359: 310-315 (2002).
    • (2002) Lancet , vol.359 , pp. 310-315
    • Bahn, S.1    Mimmack, M.2    Ryan, M.3    Caldwell, M.A.4    Jauniaux, E.5    Starkey, M.6
  • 37
    • 77949470143 scopus 로고    scopus 로고
    • Increased soluble APPalpha, Abeta 1-42, and anti-Abeta 1-42 antibodies in plasma from down syndrome patients
    • Conti E, Galimberti G, Piazza F, Raggi ME, Ferrarese C. Increased soluble APPalpha, Abeta 1-42, and anti-Abeta 1-42 antibodies in plasma from down syndrome patients. Alzheimer Dis Assoc Disord 24: 96-100 (2010).
    • (2010) Alzheimer Dis Assoc Disord , vol.24 , pp. 96-100
    • Conti, E.1    Galimberti, G.2    Piazza, F.3    Raggi, M.E.4    Ferrarese, C.5
  • 38
    • 79959407483 scopus 로고    scopus 로고
    • Increased secreted amyloid precursor protein-alpha (sAPPalpha) in severe autism: Proposal of a specific, anabolic pathway and putative biomarker
    • Ray B, Long JM, Sokol DK, Lahiri DK. Increased secreted amyloid precursor protein-alpha (sAPPalpha) in severe autism: proposal of a specific, anabolic pathway and putative biomarker. PLoS One 6: e20405, (2011).
    • (2011) PLoS One , vol.6
    • Ray, B.1    Long, J.M.2    Sokol, D.K.3    Lahiri, D.K.4


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