Sensitivity of heterozygous α1,6-fucosyltransferase knock-out mice to cigarette smoke-induced emphysema: Implication of aberrant transforming growth factor-β signaling and matrix metalloproteinase gene expression

Journal of Biological Chemistry

Volumn 287, Issue 20, 2012, Pages 16699-16708

  Gao, Congxiao ^a,b   Maeno, Toshitaka ^c   Ota, Fumi ^a,b   Ueno, Manabu ^c   Korekane, Hiroaki ^a,b   Takamatsu, Shinji ^a,b   Shirato, Ken ^a,d   Matsumoto, Akio ^a,e   Kobayashi, Satoshi ^b   Yoshida, Keiichi ^b   Kitazume, Shinobu ^b   Ohtsubo, Kazuaki ^a,b   Betsuyaku, Tomoko ^f   Taniguchi, Naoyuki ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d WASEDA UNIVERSITY   (Japan)

^e CHIBA UNIVERSITY   (Japan)

^f KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; GENE EXPRESSION; MAMMALS; TOBACCO;

CIGARETTE SMOKES; DISEASE PROCESS; EMBRYONIC FIBROBLASTS; EXPRESSION LEVELS; GENETIC DISRUPTION; MATRIX METALLOPROTEINASES; RECEPTOR SIGNALING; TRANSFORMING GROWTH FACTOR BETA;

SMOKE;

FUCOSYLTRANSFERASE; GELATINASE B; MATRIX METALLOPROTEINASE; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE COURSE; EMPHYSEMA; ENZYME ACTIVITY; FEMALE; FIBROBLAST; FUCOSYLATION; GENE EXPRESSION; HETEROZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; LUNG PARENCHYMA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RISK FACTOR; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SMOKE INDUCED EMPHYSEMA; UPREGULATION;

MUS;

EID: 84860855463     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.315333     Document Type: Article

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