Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors

Medical Gas Research

Volumn 1, Issue 1, 2011, Pages

  Kang, Ki Mun ^a   Kang, Young Nam ^a   Choi, Ihil Bong ^a,b   Gu, Yeunhwa ^b,c   Kawamura, Tomohiro ^d   Toyoda, Yoshiya ^d   Nakao, Atsunori ^d,e  

^a Gyeongsang National University   (South Korea)

^b The Catholic University of Korea College of Medicine   (South Korea)

^c SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRINKING WATER; HYDROGEN; PLACEBO; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ANOREXIA; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DIARRHEA; DOWN REGULATION; FEMALE; FLUID INTAKE; FLUID THERAPY; GASTROINTESTINAL SYMPTOM; HUMAN; LIVER CANCER; MALE; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION EXPOSURE; RADIATION INDUCED EMESIS; RADIATION INJURY; RADIATION PROTECTION; RADIATION RESPONSE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SUPPLEMENTATION; TASTE DISORDER; THERAPY EFFECT; TREATMENT OUTCOME;

EID: 84855406078     PISSN: None     EISSN: 20459912     Source Type: Journal    
DOI: 10.1186/2045-9912-1-11     Document Type: Article

References (27)

1. The Swedish Council on Technology Assessment in Health Care (SBU) systematic overview of radiotherapy for cancer including a prospective survey of radiotherapy practice in Sweden 2001 - summary and conclusions. Ringborg U, Bergqvist D, Brorsson B, Cavallin-Stahl E, Ceberg J, Einhorn N, Frodin JE, Jarhult J, Lamnevik G, Lindholm C, Littbrand B, Norlund A, Nylen U, Rosen M, Svensson H, Moller TR, Acta Oncol 2003 42 5-6 357 65 10.1080/02841860310010826 14596499 (Pubitemid 37193830)
2. Inflammation and chronic oxidative stress in radiation-induced late normal tissue injury: therapeutic implications. Zhao W, Robbins ME, Curr Med Chem 2009 16 2 130 43 10.2174/092986709787002790 19149566
3. Radioprotectors and mitigators of radiation-induced normal tissue injury. Citrin D, Cotrim AP, Hyodo F, Baum BJ, Krishna MC, Mitchell JB, Oncologist 2010 15 4 360 71 10.1634/theoncologist.2009-S104 20413641
4. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S, Nat Med 2007 13 6 688 94 10.1038/nm1577 17486089 (Pubitemid 46889750)
5. Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Buchholz BM, Kaczorowski DJ, Sugimoto R, Yang R, Wang Y, Billiar TR, McCurry KR, Bauer AJ, Nakao A, Am J Transplant 2008 8 10 2015 24 10.1111/j.1600-6143.2008.02359.x 18727697
6. Recent Advances in Hydrogen Research as a Therapeutic Medical Gas. Huang C, Kawamura T, Toyoda Y, Nakao A, Free Rad Res 2010 44 9 971 82 10.3109/10715762.2010.500328
7. Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease. Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, Yamaguchi H, Sakumi K, Yamakawa Y, Kido MA, Takaki A, Katafuchi T, Tanaka Y, Nakabeppu Y, Noda M, PLoS One 2009 4 9 7247 10.1371/journal.pone.0007247 19789628
8. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N, J Clin Biochem Nutr 2010 46 2 140 9 10.3164/jcbn.09-100 20216947
9. Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. Gu Y, Huang CS, Inoue T, Yamashita T, Ishida T, Kang KM, Nakao A, J Clin Biochem Nutr 2010 46 3 269 76 10.3164/jcbn.10-19 20490324
10. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S, Biochem Biophys Res Commun 2008 377 4 1195 8 10.1016/j.bbrc.2008.10.156 18996093
11. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, Kitawaki J, Imai S, Nakano K, Ohta M, Adachi T, Obayashi H, Yoshikawa T, Nutr Res 2008 28 3 137 43 10.1016/j.nutres.2008.01.008 19083400 (Pubitemid 351452069)
12. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, et al. J Natl Cancer Inst 1993 85 5 365 76 10.1093/jnci/85.5.365 8433390 (Pubitemid 23073154)
13. Resuscitation of preterm infants with reduced oxygen results in less oxidative stress than resuscitation with 100% oxygen. Ezaki S, Suzuki K, Kurishima C, Miura M, Weilin W, Hoshi R, Tanitsu S, Tomita Y, Takayama C, Wada M, Kondo T, Tamura M, J Clin Biochem Nutr 2009 44 1 111 8 10.3164/jcbn.08-221 19177196
14. Long-term effect of stereotactic body radiation therapy for primary hepatocellular carcinoma ineligible for local ablation therapy or surgical resection. Stereotactic radiotherapy for liver cancer. Kwon JH, Bae SH, Kim JY, Choi BO, Jang HS, Jang JW, Choi JY, Yoon SK, Chung KW, BMC Cancer 2010 10 475 10.1186/1471-2407-10-475 20813065
15. Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S, Cancer Chemother Pharmacol 2009 64 4 753 61 10.1007/s00280-008-0924-2 19148645
16. Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice. Sato Y, Kajiyama S, Amano A, Kondo Y, Sasaki T, Handa S, Takahashi R, Fukui M, Hasegawa G, Nakamura N, Fujinawa H, Mori T, Ohta M, Obayashi H, Maruyama N, Ishigami A, Biochem Biophys Res Commun 2008 375 3 346 50 10.1016/j.bbrc.2008.08.020 18706888
17. Oral Administration Of Hydrogen Water Prevents Chronic Allograft Nephropathy In Rat Renal Transplantation. Cardinal JS, Zhan J, Wang Y, Sugimoto R, Tsung A, McCurry KR, Billiar TR, Nakao A, Kidney Int 2009 77 2 101 9 19907413
18. Melatonin as a radioprotective agent: a review. Vijayalaxmi, Reiter RJ, Tan DX, Herman TS, Thomas CR Jr, Int J Radiat Oncol Biol Phys 2004 59 3 639 53 10.1016/j.ijrobp.2004.02.006 15183467 (Pubitemid 38748729)
19. Effects of radiation and alpha-tocopherol on saliva flow rate, amylase activity, total protein and electrolyte levels in oral cavity cancer. Chitra S, Shyamala Devi CS, Indian J Dent Res 2008 19 3 213 8 10.4103/0970-9290.42953 18797097
20. Prevention of radioinduced cystitis by orgotein: a randomized study. Sanchiz F, Milla A, Artola N, Julia JC, Moya LM, Pedro A, Vila A, Anticancer Res 1996 16 4A 2025 8 8712737 (Pubitemid 26270719)
21. Pentoxifylline and alpha-tocopherol in prevention of radiation-induced lung toxicity in patients with lung cancer. Misirlioglu CH, Demirkasimoglu T, Kucukplakci B, Sanri E, Altundag K, Med Oncol 2007 24 3 308 11 10.1007/s12032-007-0006-z 17873306 (Pubitemid 350135952)
22. Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage. Xavier S, Yamada K, Samuni AM, Samuni A, DeGraff W, Krishna MC, Mitchell JB, Biochim Biophys Acta 2002 1573 2 109 20 12399020 (Pubitemid 35217932)
23. Pros and cons of antioxidant use during radiation therapy. Prasad KN, Cole WC, Kumar B, Che Prasad K, Cancer Treat Rev 2002 28 2 79 91 10.1053/ctrv.2002.0260 12297116
24. Antioxidants and cancer therapy: a systematic review. Ladas EJ, Jacobson JS, Kennedy DD, Teel K, Fleischauer A, Kelly KM, J Clin Oncol 2004 22 3 517 28 14752075 (Pubitemid 41079781)
25. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. Bairati I, Meyer F, Gelinas M, Fortin A, Nabid A, Brochet F, Mercier JP, Tetu B, Harel F, Abdous B, Vigneault E, Vass S, Del Vecchio P, Roy J, J Clin Oncol 2005 23 24 5805 13 10.1200/JCO.2005.05.514 16027437
26. Interaction between antioxidant vitamin supplementation and cigarette smoking during radiation therapy in relation to long-term effects on recurrence and mortality: a randomized trial among head and neck cancer patients. Meyer F, Bairati I, Fortin A, Gelinas M, Nabid A, Brochet F, Tetu B, Int J Cancer 2008 122 7 1679 83 18059031 (Pubitemid 351294980)
27. Radioprotective effect of hydrogen in cultured cells and mice. Qian L, Cao F, Cui J, Huang Y, Zhou X, Liu S, Cai J, Free Radic Res 2010 44 3 275 82 10.3109/10715760903468758 20166892