Crosstalk between NSL Histone Acetyltransferase and MLL/SET Complexes: NSL Complex Functions in Promoting Histone H3K4 Di-Methylation Activity by MLL/SET Complexes

PLoS Genetics

Volumn 9, Issue 11, 2013, Pages

  Zhao, Xiaoming ^a   Su, Jiaming ^a   Wang, Fei ^a   Liu, Da ^a   Ding, Jian ^a   Yang, Yang ^a   Conaway, Joan W ^b,c   Conaway, Ronald C ^b,c   Cao, Lingling ^a   Wu, Donglu ^a   Wu, Min ^d   Cai, Yong ^a   Jin, Jingji ^a  

^a JILIN UNIVERSITY   (China)

^b STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^d WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE H3; HISTONE H4; HISTONE METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA SET DOMAIN CONTAINING FAMILY HISTONE H3K4 METHYLTRANSFERASE COMPLEX; NON SPECIFIC LETHAL HISTONE ACETYLTRANSFERASE; PROTEIN HMOF; PROTEIN NSL1; PROTEIN RBBP5; UNCLASSIFIED DRUG;

ANKRD2 GENE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; GENE; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ANALYSIS; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

ANIMALS; HEK293 CELLS; HISTONE ACETYLTRANSFERASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; MALE; METHYLATION; MULTIPROTEIN COMPLEXES; MUSCLE PROTEINS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84888245424     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003940     Document Type: Article

References (41)

1. Bannister A, Kouzarides T, (2011) Regulation of chromatin by histone modifications. Cell Res 21: 381-395.
2. Jin J, Cai Y, Li B, Conaway RC, Workman JL, et al. (2005) In and out: histone variant exchange in chromatin. Trends Biochem Sci 30: 680-687.
3. Berger SL, (2007) The complex language of chromatin regulation during transcription. Nature 447: 407-412.
4. Lee JS, Smith E, Shilatifard A, (2010) The language of histone crosstalk. Cell 142: 682-685.
5. Cedar H, Bergman Y, (2009) Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet 10: 295-304.
6. Suganuma T, Workman JL, (2008) Crosstalk among histone modifications. Cell 135: 604-607.
7. Daujat S, Bauer UM, Shah V, Turner B, Berger S, et al. (2002) Crosstalk between CARM1 methylation and CBP acetylation on histone H3. Curr Biol 12: 2090-2097.
8. Lee JS, Shukla A, Schneider J, Swanson SK, Washburn MP, et al. (2007) Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell 131: 1084-1096.
9. Neal KC, Pannuti A, Smith ER, Lucchesi JC, (2000) A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. Biochim Biophys Acta 1490: 170-174.
10. Carrozza MJ, Utley RT, Workman JL, Côté J, (2003) The divers functions of histone acetyltransferase complexes. Trends Genet 19: 321-329.
11. Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, et al. (2008) The mammalian ortholog of Drosophla MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol 28: 397-409.
12. Sharma GG, So S, Gupta A, Kumar R, Cayrou C, et al. (2010) Pandita TK: MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol 30: 3582-3595.
13. Rea S, Xouri G, Akhtar A, (2007) Males absent on the first (MOF): from flies to humans. Oncogene 26: 5385-5394.
14. Bhadra MP, Horikoshi N, Pushpavallipvalli SN, Sarkar A, et al. (2012) The role of MOF in the ionizing radiation response is conserved in Drosophila melanogaster. Chromosoma 121: 79-90.
15. Kind J, Vaquerizas JM, Gebhardt P, Gentzel M, Luscombe NM, et al. (2008) Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila. Cell 133: 813-828.
16. Smith ER, Cayrou C, Huang R, Lane WS, Côté J, et al. (2005) A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Mol Cell Biol 25: 9175-9188.
17. Cai Y, Jin J, Swanson SK, Cole MD, Choi SH, et al. (2010) Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. J Biol Chem 285: 4268-4272.
18. Mendjan S, Taipale M, Kind J, Holz H, Gebhardt P, et al. (2006) Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. Mol Cell 21: 811-823.
19. Shogren-Knaak M, Ishii H, Sun JM, Pazin MJ, Davie JR, et al. (2006) Histone H4-K16 acetylation controls chromatin structure and protein interaction. Science 311: 844-847.
20. Horikoshi N, Kumar P, Sharma GG, Chen M, Hunt CR, et al. (2013) Gonome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression. Genome Integr 4: 3 DOI: 10.1186/2041-9414-4-3.
21. Raja SJ, Charapitsa I, Conrad T, Vaquerizas JM, Gebhardt P, et al. (2010) The nonspecific lethal complex is a transcriptional regulator in Drosophila. Mol Cell 38: 827-841.
22. Feller C, Prestel M, Hartmann H, Straub T, Söding J, et al. (2012) The MOFcontaining NSL complex associates globally with housekeeping genes, but activates only a defined subset. Nucleic Acids Res 40: 1509-1522.
23. Lam KC, Mühlpfordt F, Vaquerizas JM, Raja SJ, Holz H, et al. (2012) The NSL Complex Regulates Housekeeping Genes in Drosophila. Plos Genet 8 (6) (): e1002736.
24. Jin J, Cai Y, Yao T, Gottschalk AJ, Florens L, et al. (2005) A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. JBC 280: 41207-41212.
25. Cho YW, Hong T, Hong S, Guo H, Yu H, et al. (2007) PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. JBC 282: 20395-20406.
26. Suganuma T, Gutiérrez JL, Li B, Florens L, Swanson SK, et al. (2008) ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding. Nat Struct Mol Biol 15: 364-372.
27. Zippo A, Serafini R, Rocchigiani M, Pennacchini S, Krepelova A, et al. (2009) Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcriprion elongation. Cell 138: 1122-1136.
28. Kapoor-Vazirani P, Kagey JD, Vertino PM, (2011) SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Mol Cell Biol 31: 1594-1609.
29. Katoh H, Qin ZS, Liu R, Wang L, Li W, et al. (2011) FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by rectruiting MOF and causing displacement of PLU-1. Mol Cell 44: 770-784.
30. Akhtar A, Becker PB, (2001) The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition. EMBO Rep 2: 113-118.
31. Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, et al. (2013) Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol 20: 317-325.
32. Li X, Wu L, Corsa CA, Kunkel S, Dou Y, (2009) Two mammalian MOF complexes regulate transcription activation by distinct mechanisms. Mol Cell 36: 290-301.
33. Morales V, Straub T, Neumann MF, Mengus G, Akhtar A, et al. (2004) Functional integration of the histone acetyltransferase MOF into the dosage compensation complex. EMBO J 23: 2258-2268.
34. Wu L, Zee BM, Wang Y, Garcia BA, Dou Y, (2011) The RING Finger Protein MSL2 in the MOF Complex Is an E3 Ubiquitin Ligase for H2B K34 and Is Involved in Crosstalk with H3 K4 and K79 Methylation. Mol Cell 43: 132-144.
35. Sims RJ 3rd, Nishioka K, Reinberg D, (2003) Histone lysine methylation: a signature for chromatin function. Trends Genet 19: 629-639.
36. Malik S, Bhaumik SR, (2010) Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human. FEBS J 277: 1805-1821.
37. Thomas T, Dixon MP, Kueh AJ, Voss AK, (2008) Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture. Mol Cell Biol 28: 5093-5105.
38. Kojic S, Radojkovic D, Faulkner G, (2011) Muscle ankyrin repeat proteins: their role in striated muscle function in health and disease. Crit Rev Clin Lab Sci 48: 269-294.
39. Dignam JD, Lebovitz RM, Roeder RG, (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489.
40. Cai Y, Jin J, Gottschalk AJ, Yao T, Conaway JW, et al. (2006) Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes. Methods 40: 312-317.
41. Washburn MP, Wolters D, Yates JR 3rd, (2001) Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol 19: 242-247.