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Volumn 2, Issue 2, 2012, Pages 148-154

Severe pulmonary hypertension: The role of metabolic and endocrine disorders

Author keywords

Epigenetics; Gender; Obesity; Pulmonary hypertension; Right heart failure; Thyroid

Indexed keywords


EID: 84888242708     PISSN: 20458932     EISSN: 20458940     Source Type: Journal    
DOI: 10.4103/2045-8932.97592     Document Type: Review
Times cited : (26)

References (60)
  • 2
    • 77955056839 scopus 로고    scopus 로고
    • Cardiovascular involvement in patients with different causes of hyperthyroidism
    • Biondi B, Kahaly GJ. Cardiovascular involvement in patients with different causes of hyperthyroidism. Nat Rev Endocrinol 2010;6:431-43.
    • (2010) Nat Rev Endocrinol , vol.6 , pp. 431-443
    • Biondi, B.1    Kahaly, G.J.2
  • 3
    • 10744233940 scopus 로고    scopus 로고
    • Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
    • Gladwin MT, Sachdev V, Jison ML, Shizukuda Y, Plehn JF, Minter K, et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 2004;350:886-95.
    • (2004) N Engl J Med , vol.350 , pp. 886-895
    • Gladwin, M.T.1    Sachdev, V.2    Jison, M.L.3    Shizukuda, Y.4    Plehn, J.F.5    Minter, K.6
  • 4
    • 79960101398 scopus 로고    scopus 로고
    • A hemodynamic study of pulmonary hypertension in sickle cell disease
    • Parent F, Bachir D, Inamo J, Lionnet F, Driss F, Loko G, et al. A hemodynamic study of pulmonary hypertension in sickle cell disease. N Engl J Med 2011;365:44-53.
    • (2011) N Engl J Med , vol.365 , pp. 44-53
    • Parent, F.1    Bachir, D.2    Inamo, J.3    Lionnet, F.4    Driss, F.5    Loko, G.6
  • 5
    • 0030041787 scopus 로고    scopus 로고
    • Comparison of the hemodynamics and survival of adults with severe primary pulmonary hypertension or Eisenmenger syndrome
    • Hopkins WE, Ochoa LL, Richardson GW, Trulock EP. Comparison of the hemodynamics and survival of adults with severe primary pulmonary hypertension or Eisenmenger syndrome. J Heart Lung Transplant 1996;15:100-5.
    • (1996) J Heart Lung Transplant , vol.15 , pp. 100-105
    • Hopkins, W.E.1    Ochoa, L.L.2    Richardson, G.W.3    Trulock, E.P.4
  • 8
    • 84869089160 scopus 로고    scopus 로고
    • The genetics of pulmonary arterial hypertension in the post-BMPR2 era
    • Fessel JP, Loyd JE, Austin ED. The genetics of pulmonary arterial hypertension in the post-BMPR2 era. Pulm Circ 2011;1:305-19.
    • (2011) Pulm Circ , vol.1 , pp. 305-319
    • Fessel, J.P.1    Loyd, J.E.2    Austin, E.D.3
  • 9
    • 70350122864 scopus 로고    scopus 로고
    • Estrogen exposure, obesity and thyroid disease is women with severe pulmonary hypertension
    • Sweeney L, Voelkel N. Estrogen exposure, obesity and thyroid disease is women with severe pulmonary hypertension. Eur J Med Res 2009;14:433-42.
    • (2009) Eur J Med Res , vol.14 , pp. 433-442
    • Sweeney, L.1    Voelkel, N.2
  • 10
    • 33646731984 scopus 로고    scopus 로고
    • Severe pulmonary hypertension in postmenopausal obese women
    • Taraseviciute A, Voelkel NF. Severe pulmonary hypertension in postmenopausal obese women. Eur J Med Res 2006;11:198-202.
    • (2006) Eur J Med Res , vol.11 , pp. 198-202
    • Taraseviciute, A.1    Voelkel, N.F.2
  • 11
    • 78651415646 scopus 로고    scopus 로고
    • The changing picture of patients with pulmonary arterial hypertension in the United States: How REVEAL differs from historic and non-US Contemporary Registries
    • Frost AE, Badesch DB, Barst RJ, Benza RL, Elliott CG, Farber HW, et al. The changing picture of patients with pulmonary arterial hypertension in the United States: how REVEAL differs from historic and non-US Contemporary Registries. Chest 2011;139:128-37.
    • (2011) Chest , vol.139 , pp. 128-137
    • Frost, A.E.1    Badesch, D.B.2    Barst, R.J.3    Benza, R.L.4    Elliott, C.G.5    Farber, H.W.6
  • 13
    • 0033506532 scopus 로고    scopus 로고
    • High prevalence of hypothyroidism in patients with primary pulmonary hypertension
    • Curnock AL, Dweik RA, Higgins BH, Saadi HF, Arroliga AC. High prevalence of hypothyroidism in patients with primary pulmonary hypertension. Am J Med Sci 1999;318:289-92.
    • (1999) Am J Med Sci , vol.318 , pp. 289-292
    • Curnock, A.L.1    Dweik, R.A.2    Higgins, B.H.3    Saadi, H.F.4    Arroliga, A.C.5
  • 14
    • 0033789802 scopus 로고    scopus 로고
    • Primary pulmonary hypertension and thyroid disease
    • Arroliga AC, Dweik RA, Rafanan AL. Primary pulmonary hypertension and thyroid disease. Chest 2000;118:1224-5.
    • (2000) Chest , vol.118 , pp. 1224-1225
    • Arroliga, A.C.1    Dweik, R.A.2    Rafanan, A.L.3
  • 16
    • 84856762337 scopus 로고    scopus 로고
    • Sex differences in the diagnosis, treatment, and outcome of patients with pulmonary arterial hypertension enrolled in the registry to evaluate early and long-term pulmonary arterial hypertension disease management
    • Shapiro S, Traiger GL, Turner M, McGoon MD, Wason P, Barst RJ. Sex differences in the diagnosis, treatment, and outcome of patients with pulmonary arterial hypertension enrolled in the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Chest 2012;141:363-73
    • (2012) Chest , vol.141 , pp. 363-373
    • Shapiro, S.1    Traiger, G.L.2    Turner, M.3    McGoon, M.D.4    Wason, P.5    Barst, R.J.6
  • 18
    • 85026308112 scopus 로고    scopus 로고
    • Endocrine aspects of pulmonary hypertension
    • (NF Voelkel, ed). Shelton, Connecticut: People’s Medical Publishing House
    • Sweeney L, Chhatwani L. Endocrine aspects of pulmonary hypertension. Pulmonary hypertension: Present and Future (NF Voelkel, ed). Shelton, Connecticut: People’s Medical Publishing House; 2011. p. 239-49.
    • (2011) Pulmonary Hypertension: Present and Future , pp. 239-249
    • Sweeney, L.1    Chhatwani, L.2
  • 19
    • 62149104001 scopus 로고    scopus 로고
    • The right ventricle under pressure: Cellular and molecular mechanisms of right-heart failure in pulmonary hypertension
    • Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF. The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest 2009;135:794-804.
    • (2009) Chest , vol.135 , pp. 794-804
    • Bogaard, H.J.1    Abe, K.2    Vonk Noordegraaf, A.3    Voelkel, N.F.4
  • 21
    • 84856460014 scopus 로고    scopus 로고
    • Body mass index is directly associated with biomarkers of angiogenesis and inflammation in children and adolescents
    • Siervo M, Ruggiero D, Sorice R, Nutile T, Aversano M, Iafusco M, et al. Body mass index is directly associated with biomarkers of angiogenesis and inflammation in children and adolescents. Nutrition 2012;28:262-6
    • (2012) Nutrition , vol.28 , pp. 262-266
    • Siervo, M.1    Ruggiero, D.2    Sorice, R.3    Nutile, T.4    Aversano, M.5    Iafusco, M.6
  • 22
    • 81855225795 scopus 로고    scopus 로고
    • Molecular mechanisms of cancer development in obesity
    • Khandekar MJ, Cohen P, Spiegelman BM. Molecular mechanisms of cancer development in obesity. Nat Rev Cancer 2011;11:886-95.
    • (2011) Nat Rev Cancer , vol.11 , pp. 886-895
    • Khandekar, M.J.1    Cohen, P.2    Spiegelman, B.M.3
  • 23
    • 77955676030 scopus 로고    scopus 로고
    • Prevalence and risk factors of pulmonary hypertension in patients with elevated pulmonary venous pressure and preserved ejection fraction
    • Leung CC, Moondra V, Catherwood E, Andrus BW. Prevalence and risk factors of pulmonary hypertension in patients with elevated pulmonary venous pressure and preserved ejection fraction. Am J Cardiol 2010;106: 284-6.
    • (2010) Am J Cardiol , vol.106 , pp. 284-286
    • Leung, C.C.1    Moondra, V.2    Catherwood, E.3    Rus, B.W.4
  • 24
    • 0035023128 scopus 로고    scopus 로고
    • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
    • Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 2001;280:E745-51.
    • (2001) Am J Physiol Endocrinol Metab , vol.280 , pp. E745-E751
    • Kern, P.A.1    Ranganathan, S.2    Li, C.3    Wood, L.4    Ranganathan, G.5
  • 25
    • 53749092291 scopus 로고    scopus 로고
    • Complications of pediatric livedonor kidney transplantation: A single center’s experience in Egypt
    • El-Husseini AA, Sobh MA, Ghoneim MA. Complications of pediatric livedonor kidney transplantation: a single center’s experience in Egypt. Pediatr Nephrol 2008;23:2067-73.
    • (2008) Pediatr Nephrol , vol.23 , pp. 2067-2073
    • El-Husseini, A.A.1    Sobh, M.A.2    Ghoneim, M.A.3
  • 26
    • 77954470456 scopus 로고    scopus 로고
    • Vitamin D insuffiency, deficiency, and bone health
    • Gallagher J, Sai A. Vitamin D insuffiency, deficiency, and bone health. J Clin Endocrinol Metab 2010;95:2630-3.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2630-2633
    • Gallagher, J.1    Sai, A.2
  • 27
    • 73649147052 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcomaassociated herpes virus G protein-coupled receptor in vitro and in vivo
    • Gonzalez-Pardo V, Martin D, Gutkind JS, Verstuyf A, Bouillon R, de Boland AR, et al. 1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcomaassociated herpes virus G protein-coupled receptor in vitro and in vivo. Endocrinology 2010;151:23-31.
    • (2010) Endocrinology , vol.151 , pp. 23-31
    • Gonzalez-Pardo, V.1    Martin, D.2    Gutkind, J.S.3    Verstuyf, A.4    Bouillon, R.5    De Boland, A.R.6
  • 28
    • 78650905925 scopus 로고    scopus 로고
    • Vitamin D in atherosclerosis, vascular disease, and endothelial function
    • Brewer LC, Michos ED, Reis JP. Vitamin D in atherosclerosis, vascular disease, and endothelial function. Curr Drug Targets 2011;12:54-60.
    • (2011) Curr Drug Targets , vol.12 , pp. 54-60
    • Brewer, L.C.1    Michos, E.D.2    Reis, J.P.3
  • 29
    • 84856999767 scopus 로고    scopus 로고
    • An update on vitamin D and human immunity
    • Hewison M. An update on vitamin D and human immunity. Clin Endocrinol (Oxf) 2012;76:315-25.
    • (2012) Clin Endocrinol (Oxf) , vol.76 , pp. 315-325
    • Hewison, M.1
  • 30
    • 34248143459 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells
    • Ben-Shoshan M, Amir S, Dang DT, Dang LH, Weisman Y, Mabjeesh NJ. 1alpha,25-dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells. Mol Cancer Ther 2007;6:1433-9.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1433-1439
    • Ben-Shoshan, M.1    Amir, S.2    Dang, D.T.3    Dang, L.H.4    Weisman, Y.5    Mabjeesh, N.J.6
  • 31
    • 78650676621 scopus 로고    scopus 로고
    • Vitamin D: An instrumental factor in the anti-phospholipid syndrome by inhibition of tissue factor expression
    • Agmon-Levin N, Blank M, Zandman-Goddard G, Orbach H, Meroni PL, Tincani A, et al. Vitamin D: An instrumental factor in the anti-phospholipid syndrome by inhibition of tissue factor expression. Ann Rheum Dis 2011;70:145-50.
    • (2011) Ann Rheum Dis , vol.70 , pp. 145-150
    • Agmon-Levin, N.1    Blank, M.2    Zandman-Goddard, G.3    Orbach, H.4    Meroni, P.L.5    Tincani, A.6
  • 33
    • 49349084463 scopus 로고    scopus 로고
    • Parathyroid hormone effectively induces mobilization of progenitor cells without depletion of bone marrow
    • Brunner S, Zaruba MM, Huber B, David R, Vallaster M, Assmann G, et al. Parathyroid hormone effectively induces mobilization of progenitor cells without depletion of bone marrow. Exp Hematol 2008;36:1157-66.
    • (2008) Exp Hematol , vol.36 , pp. 1157-1166
    • Brunner, S.1    Zaruba, M.M.2    Huber, B.3    David, R.4    Vallaster, M.5    Assmann, G.6
  • 34
    • 54349126907 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates the endothelial expression of vascular endothelial growth factor
    • Rashid G, Bernheim J, Green J, Benchetrit S. Parathyroid hormone stimulates the endothelial expression of vascular endothelial growth factor. Eur J Clin Invest 2008;38:798-803.
    • (2008) Eur J Clin Invest , vol.38 , pp. 798-803
    • Rashid, G.1    Bernheim, J.2    Green, J.3    Benchetrit, S.4
  • 35
    • 73349125475 scopus 로고    scopus 로고
    • Dual role of parathyroid hormone in endothelial progenitor cells and marrow stromal mesenchymal stem cells
    • Di Bernardo G, Galderisi U, Fiorito C, Squillaro T, Cito L, Cipollaro M, et al. Dual role of parathyroid hormone in endothelial progenitor cells and marrow stromal mesenchymal stem cells. J Cell Physiol 2010;222:474-80.
    • (2010) J Cell Physiol , vol.222 , pp. 474-480
    • Di Bernardo, G.1    Galderisi, U.2    Fiorito, C.3    Squillaro, T.4    Cito, L.5    Cipollaro, M.6
  • 38
    • 34249852339 scopus 로고    scopus 로고
    • Hemodynamic changes in hyperthyroidism-related pulmonary hypertension: A prospective echocardiographic study
    • Siu CW, Zhang XH, Yung C, Kung AW, Lau CP, Tse HF. Hemodynamic changes in hyperthyroidism-related pulmonary hypertension: A prospective echocardiographic study. J Clin Endocrinol Metab 2007;92:1736-42.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1736-1742
    • Siu, C.W.1    Zhang, X.H.2    Yung, C.3    Kung, A.W.4    Lau, C.P.5    Tse, H.F.6
  • 40
    • 13444271660 scopus 로고    scopus 로고
    • Cardiovascular abnormalities in hyperthyroidism: A prospective Doppler echocardiographic study
    • Merce J, Ferras S, Oltra C, Sanz E, Vendrell J, Simon I, et al. Cardiovascular abnormalities in hyperthyroidism: A prospective Doppler echocardiographic study. Am J Med 2005;118:126-31.
    • (2005) Am J Med , vol.118 , pp. 126-131
    • Merce, J.1    Ferras, S.2    Oltra, C.3    Sanz, E.4    Vendrell, J.5    Simon, I.6
  • 41
    • 33749860155 scopus 로고    scopus 로고
    • Hyperthyroidism as a cause of pulmonary arterial hypertension: A prospective study
    • Armigliato M, Paolini R, Aggio S, Zamboni S, Galasso MP, Zonzin P, et al. Hyperthyroidism as a cause of pulmonary arterial hypertension: A prospective study. Angiology 2006;57:600-6.
    • (2006) Angiology , vol.57 , pp. 600-606
    • Armigliato, M.1    Paolini, R.2    Aggio, S.3    Zamboni, S.4    Galasso, M.P.5    Zonzin, P.6
  • 42
    • 12244286039 scopus 로고    scopus 로고
    • Systolic pulmonary artery pressure and serum uric acid levels in patients with hyperthyroidism
    • Yazar A, Doven O, Atis S, Gen R, Pata C, Yazar EE, et al. Systolic pulmonary artery pressure and serum uric acid levels in patients with hyperthyroidism. Arch Med Res 2003;34:35-40.
    • (2003) Arch Med Res , vol.34 , pp. 35-40
    • Yazar, A.1    Doven, O.2    Atis, S.3    Gen, R.4    Pata, C.5    Yazar, E.E.6
  • 43
    • 34547865714 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF), VEGF receptors expression and microvascular density in benign and malignant thyroid diseases
    • Jebreel A, England J, Bedford K, Murphy J, Karsai L, Atkin S. Vascular endothelial growth factor (VEGF), VEGF receptors expression and microvascular density in benign and malignant thyroid diseases. Int J Exp Pathol 2007;88:271-7.
    • (2007) Int J Exp Pathol , vol.88 , pp. 271-277
    • Jebreel, A.1    England, J.2    Bedford, K.3    Murphy, J.4    Karsai, L.5    Atkin, S.6
  • 44
    • 0040316990 scopus 로고    scopus 로고
    • Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells
    • Lin HY, Shih A, Davis FB, Davis PJ. Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells. Biochem J 1999;338:427-32.
    • (1999) Biochem J , vol.338 , pp. 427-432
    • Lin, H.Y.1    Shih, A.2    Davis, F.B.3    Davis, P.J.4
  • 48
    • 34249062965 scopus 로고    scopus 로고
    • Hypoxia and the lung: Beyond hypoxic vasoconstriction
    • Nicolls MR, Voelkel NF. Hypoxia and the lung: Beyond hypoxic vasoconstriction. Antioxid Redox Signal 2007;9:741-3.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 741-743
    • Nicolls, M.R.1    Voelkel, N.F.2
  • 49
    • 84865606781 scopus 로고    scopus 로고
    • Progenitor cells in pulmonary vascular remodeling
    • Yeager ME, Frid MG, Stenmark KR. Progenitor cells in pulmonary vascular remodeling. Pulm Circ 2011;1:3-16.
    • (2011) Pulm Circ , vol.1 , pp. 3-16
    • Yeager, M.E.1    Frid, M.G.2    Stenmark, K.R.3
  • 50
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, et al. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. Faseb J 2001; 15: 427-38.
    • (2001) Faseb J , vol.15 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc Mahon, G.5    Waltenberger, J.6
  • 51
    • 21744460365 scopus 로고    scopus 로고
    • Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells
    • Sakao S, Taraseviciene-Stewart L, Lee JD, Wood K, Cool CD, Voelkel NF. Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells. FASEB J 2005;19:1178-80.
    • (2005) FASEB J , vol.19 , pp. 1178-1180
    • Sakao, S.1    Taraseviciene-Stewart, L.2    Lee, J.D.3    Wood, K.4    Cool, C.D.5    Voelkel, N.F.6
  • 53
    • 77954243018 scopus 로고    scopus 로고
    • Formation of plexiform lesions in experimental severe pulmonary arterial hypertension
    • Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, et al. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation 2010;121:2747-54.
    • (2010) Circulation , vol.121 , pp. 2747-2754
    • Abe, K.1    Toba, M.2    Alzoubi, A.3    Ito, M.4    Fagan, K.A.5    Cool, C.D.6
  • 54
    • 34147189502 scopus 로고    scopus 로고
    • Rho Kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
    • Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, et al. Rho Kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res 2007; 100:923-9.
    • (2007) Circ Res , vol.100 , pp. 923-929
    • Oka, M.1    Homma, N.2    Taraseviciene-Stewart, L.3    Morris, K.G.4    Kraskauskas, D.5    Burns, N.6
  • 57
    • 0031707153 scopus 로고    scopus 로고
    • Thyroid hormone receptor is a negative regulator in p53-mediated signaling pathways
    • Barrera-Hernandez G, Zhan Q, Wong R, Cheng SY. Thyroid hormone receptor is a negative regulator in p53-mediated signaling pathways. DNA Cell Biol 1998;17:743-50.
    • (1998) DNA Cell Biol , vol.17 , pp. 743-750
    • Barrera-Hernandez, G.1    Zhan, Q.2    Wong, R.3    Cheng, S.Y.4
  • 58
    • 33847060499 scopus 로고    scopus 로고
    • Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is antiapoptotic
    • Lin HY, Tang HY, Shih A, Keating T, Cao G, Davis PJ, et al. Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is antiapoptotic. Steroids 2007;72:180-7.
    • (2007) Steroids , vol.72 , pp. 180-187
    • Lin, H.Y.1    Tang, H.Y.2    Shih, A.3    Keating, T.4    Cao, G.5    Davis, P.J.6
  • 60
    • 77951218481 scopus 로고    scopus 로고
    • Influence of sex hormones and phytoestrogens on heart disease in men and women
    • Bhupathy P, Haines CD, Leinwand LA. Influence of sex hormones and phytoestrogens on heart disease in men and women. Womens Health (Lond Engl) 2010;6:77-95.
    • (2010) Womens Health (Lond Engl) , vol.6 , pp. 77-95
    • Bhupathy, P.1    Haines, C.D.2    Leinwand, L.A.3


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