Thyroid hormone receptor is a negative regulator in p53-mediated signaling pathways

DNA and Cell Biology

Volumn 17, Issue 9, 1998, Pages 743-750

  Barrera Hernandez, Gonzalo ^a   Zhan, Qimin ^a   Wong, Rosemary ^b   Cheng, Sheue Yann ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; THYROID HORMONE RECEPTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; DNA BINDING; GENE MAPPING; GENE TARGETING; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; RECEPTOR UPREGULATION; TUMOR SUPPRESSOR GENE;

EID: 0031707153     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1998.17.743     Document Type: Article

References (30)

1. ANDERSON, M.E., WOELKER, B., REED, M., WANG, P., and TEGTMEYER, P. (1997). Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation. Mol. Cel. Biol. 17, 6255-6264.
2. AVANTAGGIATI, M.L., OGRYZKO, V., GARDNER, K., GIORDANO, A., LEVINE, A.S., and KELLY, K. (1997). Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89, 1175-1184.
3. BARGONETTI, J., MANFREDI, J.J., CHEN, X., MARSHAK, D.R., and PRIVES, C. (1993). A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53-protein. Genes Div. 7, 2565-2574.
4. BHAT, M.K., PARKISON, C., McPHIE, P., LIANG, C.-M., and CHENG, S.-Y. (1993). Conformational changes of human β1 thyroid hormone receptor induced by binding of 3,3′,5-triiodo-L-thyronine. Biochem. Biophys. Res. Commun. 195, 385-392.
5. BHAT, M.K., YU, C.-L., YAP, N., ZHAN, Q., HAYASHI, Y., SETH, P., and CHENG, S.-Y. (1997). Tumor suppressor p53 is a negative regulator in thyroid hormone receptor signaling pathways. J. Biol. Chem. 272, 28989-28993.
6. CHAKRAVARTI, D., LAMORTE, V.J., NELSON, M.C., NAKAJIMA, T., SCHULMAN, I.G., JUGUILON, H., MONTMINY, M., and EVANS, R.M. (1996). Role of CBP/p300 in nuclear receptor signalling. Nature 383, 99-103.
7. CHENG, S.-Y. (1995). New insights into the structure and function of the thyroid hormone receptor. J. Biomed. Sci. 2, 77-89.
8. CHOMCZYNSKI, P., and SACCHI, N. (1987). Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
9. DeFESI, C.R., and SURKS, M.I. (1981). 3,5,3′-Triiodothyronine effects on the growth rate and cell cycle of cultured GC cells. Endocrinology 108, 259-267.
10. DeFESI, C.R., FELS, E.G., and SURKS, M.I. (1984). Triiodothyronine stimulates growth of cultured GC cells by action early in the G1 period. Endocrinology 114, 293-295.
11. 3 receptor. Endocrinology 116, 2062-2069.
12. EL-DEIRY, W.S., KERN, S.E., PIETENPOL., J.A., KINZLER, K.W., and VOGELSTEIN, B. (1992). Definition of a consensus binding site for p53. Nature Genet. 1, 45-49.
13. EL-DEIRY, W.S., TORINO, T., VELCULESCU, V.E., LEVY, D.B., PARSONS, R., TRENT, J.M., LIN, D., MERCER, W.E., KINZLER, K.W., and VOGELSTEIN, B. (1993). Waf1, a potential mediator of p53 tumor suppression. Cell 75, 817-825.
14. FAN, S., SMITH, M.L., RIVET, D.J. II, DUBA, D., ZHAN, Q., HOHN, K.W., FORNACE, A.J. JR., and O'CONNOR, P.M. (1995). Disruption of p53 function sensitizes breast cancer MCF-7 cells to cis-platin and pentoxifylline. Cancer Res. 55, 1649-1654.
15. GU, W., SHI, X.-L., and ROEDER, R.G. (1997). Synergistic activation of transcription by CBP and p53. Nature 387, 819-823.
16. GUERNSEY, D.L., and FISHER, P.B. (1990). Thyroid hormone and neoplastic transformation. Crit. Rev. Oncogenesis 1, 389-408.
17. HALAZONETIS, T.D., and KANDIL, A.N. (1993). Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA-binding domain and restore DNA-binding to select p53 mutants. EMBO J. 12, 5057-5064.
18. HAYASHI, Y., MANGOURA, D., and REFETOFF, S. (1996). A mouse model of resistance to thyroid hormone produced by somatic gene transfer of a mutant thyroid hormone receptor. Mol. Endocrinol. 10, 100-106.
19. HOLLANDER, M.C., and FORNACE, A.J. JR. (1989). Induction of fos RNA by DNA-damaging agents. Cancer Res. 49, 1687-1692.
20. HOLLANDER, M.C., and FORNACE, A.J. JR. (1990). Estimation of relative mRNA content by filter hybridization to a polythymidylate probe. Biotechniques 9, 174-179.
21. HOLLSTEIN, M., RICE, K., GREENBLATT, M.S., SOUSSI, T., FUCHS, R., SORLIE, T., HOVIG, E., SMITH-SORENSEN, B., MONTESANO, R., and HARRIS, C.C (1994). Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res. 22, 3551-3555.
22. KATAYOSE, D., GUDAS, J., NGUYEN, H., SRIVASTAVA, S., COWAN, K.H., and SETH, P. (1995). Cytotoxic effects of adenovirus-mediated wild-type p53 protein expression in normal and tumor mammary epithelial cells. Clin. Cancer Res. 1, 889-897.
23. KESSIS, T.D., SLEBOS, R.J., NELSON, W.G., KASTAN, M.B., PLUNKETT, B.S., HAN, S.M., LORINCZ, A.T., HEDRICK, L., and CHO, K.R. (1993). Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc. Natl. Acad. Sci. USA 90, 3988-3992.
24. PAPATHANASIOU, M.A., KERR, N.C., ROBBINS, J.H., MCBRIDE, D.W., ALAMO, I.J., BARRET, S.F., HICKSON, I.D., and FORNACE, A.J. JR. (1991). Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C. Mol. Cell. Biol. 11, 1009-1016.
25. PAVLETICH, N.P., CHAMBERS, K.A., and PABO, C.O. (1993). The DNA-binding domain of p53 contains the 4 conserved regions and the major mutation hot-spots. Genes Dev. 7, 2556-2564.
26. PERRY, M.E., and LEVINE, A.J. (1993). Tumor-suppressor p53 and the cell cycle. Curr. Opin. Genes Dev. 3, 50-54.
27. PICKSLEY, S.M., and LANE, D.P. (1994). p53 and Rb: their cellular roles. Curr. Opin. Cell Biol. 6, 853-858.
28. PIETENPOL, J.A., and VOGELSTEIN, B. (1993). No room at the p53 inn. Nature 365, 17-18.
29. PRIVES, C., and MANFREDI, J.J. (1993). The p53 tumor suppressor protein: meeting review. Genes Dev. 7, 529-534.
30. SELIVANOVA, G., and WIMAN, K.G. (1995). p53: a cell cycle regulator activated by DNA damage. Adv. Cancer Res. 66, 143-180.