Optimal treatment opportunity for mTHPC-mediated photodynamic therapy of liver cancer

Lasers in Medical Science

Volumn 28, Issue 6, 2013, Pages 1541-1548

  Wang, Jian Dong ^a   Shen, Jun ^a   Zhou, Xue Ping ^a   Shi, Wei Bin ^a   Yan, Jiang Hua ^b   Luo, Fang Hong ^b   Quan, Zhi Wei ^a  

^a XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Biodistribution; Fluorescence method; Liver cancer; mTHPC; Pharmacokinetics; Photodynamic therapy

Indexed keywords

TETRAKIS(3 HYDROXYPHENYL)CHLORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG TISSUE LEVEL; FEASIBILITY STUDY; FLUORESCENCE SPECTROSCOPY; LIVER CANCER; MALE; NONHUMAN; PHOTODYNAMIC THERAPY; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

ANIMALS; CARCINOMA 256, WALKER; CELL LINE, TUMOR; HALF-LIFE; INJECTIONS, INTRAVENOUS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MESOPORPHYRINS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RATS; RATS, WISTAR; SPECTROMETRY, FLUORESCENCE; TISSUE DISTRIBUTION;

EID: 84888205935     PISSN: 02688921     EISSN: 1435604X     Source Type: Journal    
DOI: 10.1007/s10103-012-1248-3     Document Type: Article

References (23)

1. Bosch FX, Ribes J, Diaz M, Cléries R (2004) Primary liver cancer: worldwide incidence and trends. Gastroenterology 127(5 Suppl 1):S5-S16
2. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ, Thun MJ (2005) Cancer statistics. CA Cancer J Clin 55:10-30
3. Huang Z, Xu H, Meyers AD, Musani AI, Wang L, Tagg R, Barqawi AB, Chen YK (2008) Photodynamic therapy for treatment of solid tumors: potential and technical challenges. Technol Cancer Res Treat 7:309-320
4. Huang Z (2006) Photodynamic therapy in China: 25 years of unique history - part two: clinical experience. Photodiagnosis Photodyn Ther 3:71-84
5. Chen B, Xu Y, Roskams T, Delaey E, Agostinis P, Vandenheede JR, de Witte P (2001) Efficacy of antitumoral photodynamic therapy with hypericin: relationship between biodistribution and photodynamic effects in the RIF-1 mouse tumor model. Int J Cancer 93:275-282
6. Gossner L, Stolte M, Seitz G, Hahn EG, Stewart C, Ell C (1996) mTHPC for photodynamic therapy of early gastric cancer [abstract]. Gastroenterology 110:A521
7. Lovat LB, Whitelaw DE, Spencer GM, Thorpe SM, Mlkvy PP, Buonaccorsi G, Bown SG (1999) Photodynamic therapy for gastrointestinal tumours using mTHPC [abstract]. Gastroenterology 116:A456
8. Fan K, Hopper C, Speight P, Bown S (1996) Photodynamic therapy using a new photosensitiser, mTHPC, in the treatment of oral cancer. J Dental Res 75:1164
9. Garrier J, Bressenot A, Gräfe S, Marchal S, Mitra S, Foster TH, Guillemin F (2010) Compartmental targeting for mTHPC based photodynamic treatment in vivo: correlation between efficiency, pharmacokinetics and regional distribution of apoptosis. Int J Radiat Oncol Biol Phys 78:563-571
10. Kascáková S, Kruijt B, de Bruijn HS, van der Ploeg-van den Heuvel A, Robinson DJ, Sterenborg HJ, Amelink A (2008) Ex vivo quantification of mTHPC concentration in tissue: influence of chemical extraction on the optical properties. J Photochem Photobiol B 91(2-3):99-107, 91
11. Lilge L, O'Carroll C, Wilson BC (1997) A solubilization technique for photosensitizer quantification in ex vivo tissue samples. J Photochem Photobiol B 39:229-235
12. Chen JY, Mak NK, Yow CM, Fung MC, Chiu LC, Leung WN, Cheung NH (2000) The binding characteristics and intracellular localization of temoporfin (mTHPC) in myeloid leukemia cells: phototoxicity and mitochondrial damage. Photochem Photobiol 72:541-547
13. Glanzmann T, Hadjur C, Zellweger M, Grosiean P, Forrer M, Ballini JP, Monnier P, Van den Bergh H, Lim CK, Wagnieres G (1998) Pharmacokinetics of tetra(m-hydroxyphenyl) chlorin in human plasma and individualized light dosimetry in photodynamic therapy. Photochem Photobiol 67:596-602
14. Jones HJ, Vernon DI, Brown SB (2003) Photodynamic therapy effect of mTHPC (Foscan) in vivo: correlation with pharmacokinetics. Br J Cancer 89:398-404
15. Cramers P, Ruevekamp M, Oppelaar H, Dalesio O, Baas P, Stewart FA (2003) Foscan uptake and tissue distribution in relation to photodynamic efficacy. Br J Cancer 88:283-290
16. Lassalle HP, Dumas D, Gräfe S, D'Hallewin MA, Guillemin F, Bezdetnaya L (2009) Correlation between in vivo pharmacokinetics, intratumoral distribution and photodynamic efficiency of liposomal mTHPC. J Control Release 134(2):118-124
17. Ronn AM, Batti J, Lee CJ, Yoo D, Siegel ME, Nouri M, Lofgren LA, Steinberg BM (1997) Comparative biodistribution of meta-tetra(hydroxyphenyl) chlorin in multiple species: clinical implications for photodynamic therapy. Lasers Surg Med 20(4):437-442
18. Campbell GA, Bartels KE, Arnold C, Healey T, Cowell RL, Lucroy MD, Ronn AM (2002) Tissue levels, histologic changes and plasma pharmacokinetics of meta-tetra (hydroxyphenyl) chlorin (mTHPC) in the cat. Lasers Med Sci 17(2):79-85
19. 14C-labelled meta-tetrahydroxyphenylchlorin and 5-aminolaevulinic acid in the C6 rat glioma model. Br J Cancer 78:733-738
20. Rovers JP, Saarnak AE, de Jode M, Sterenborg HJ, Terpstra OT, Grahn MF (2000) Biodistribution and bioactivity of tetra-pegylated meta- tetra(hydroxyphenyl)chlorin compared to native meta-tetra(hydroxyphenyl)chlorin in a rat liver tumor model. Photochem Photobiol 71(2):211-217
21. Rovers JP, de Jode ML, Grahn MF (2000) Significantly increased lesion size by using the near-infrared photosensitizer 5,10,15,20-tetrakis (m-hydroxyphenyl)bacteriochlorin in interstitial photodynamic therapy of normal rat liver tissue. Lasers Surg Med 27:235-240
22. Whelpton R, Michael-Titus AT, Basra SS, Grahn M (1995) Distribution of temoporfin, a new photosensitizer for the photodynamic therapy of cancer, in a murine tumor model. Photochem Photobiol 61:397-401
23. Veenhuizen RB, Ruevekamp MC, Oppelaar H, Helmerhorst TJ, Kenemans P, Stewart FA (1997) Foscan-mediated photodynamic therapy for a peritoneal-cancer model: drug distribution and efficacy studies. Int J Cancer 73(2):230-235