Uptake and kinetics of 14C-labelled meta-tetrahydroxyphenylchlorin and 5-aminolaevulinic acid in the C6 rat glioma model

British Journal of Cancer

Volumn 78, Issue 6, 1998, Pages 733-738

  Obwegeser, A ^a,b   Jakober, R ^a   Kostron, H ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b Universitatsklinik fur Neurochirurgie Innsbruck   (Austria)

Author keywords

5 Aminolaevulinic acid; Brain tumour; Glioma; m THPC; Photodynamic therapy

Indexed keywords

AMINOLEVULINIC ACID; PHOTOSENSITIZING AGENT; TETRA(HYDROXYPHENYL)CHLORIN; UNCLASSIFIED DRUG; CARBON; DIAGNOSTIC AGENT; MESOPORPHYRIN; TEMOPORFIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG LIVER LEVEL; DRUG TUMOR LEVEL; DRUG UPTAKE; GLIOMA; INTRAPERITONEAL DRUG ADMINISTRATION; ISOTOPE LABELING; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RAT; SKIN; ANIMAL; BRAIN; DISEASE MODEL; FEMALE; METABOLISM; SCINTISCANNING;

AMINOLEVULINIC ACID; ANIMALS; BRAIN; BRAIN NEOPLASMS; CARBON RADIOISOTOPES; DISEASE MODELS, ANIMAL; FEMALE; GLIOMA; MESOPORPHYRINS; PHOTOSENSITIZING AGENTS; RATS;

EID: 0031596309     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.569     Document Type: Article

References (33)

1. Alian W, Andersson Engels S, Svanberg K and Svanberg S (1994) Laser-induced fluorescence studies of meso-tetra(hydroxyphenyl)chlorin in malignant and normal tissues in rats. Br J Cancer 70: 880-885
2. Bedwell J, Macrobert AJ, Phillips D, Brown SG and Bown SG (1992) Fluorescence distribution and photodynamic effect of ALA-induced PPIX in the DMH rat clonic tumour model. Br J Cancer 65: 818-824
3. Bonnett R and Berenbaum MC (1989) Porphyrins as photosensitizers. Ciba Found Symp 146: 40-53
4. Braichotte D, Savary JF, Glanzmann T, Westermann P, Folli S, Wagnieres G, Monnier P and Van-den-Bergh H (1995) Clinical pharmacokinetic studies of tetra(meta-hydroxyphenyl)chlorin in squamous cell carcinoma by fluorescence spectroscopy at 2 wavelengths. Int J Cancer 63: 198-204
5. Burger PC (1990) Classification, trading, and patterns of spread of malignant gliomas. In Malignant Cerebral Glioma. Apuzzo MLJ (ed.), pp. 3-17. American Association of Neurological Surgeons: Park Ridge, USA.
6. Cairnduff F, Stringer MR, Hudson EJ, Ash DV and Brown SB (1994) Superficial photodynamic therapy with topical 5-aminolaevulinic acid for superficial primary and secondary skin cancer. Br J Cancer 69: 605-608
7. Chicoine MR and Silbergeld DL (1995) Invading C6 glioma cells maintaining tumorigenicity. J Neurosurg 83: 665-671
8. Gibson SL, Cohen HJ and Hilf R (1984) Evidence against the production of superoxide by photoirradiation of hematoporphyrin derivate. Photochem Photobiol 40: 441-448
9. Jocham D (1994) Photodynamic procedures in urology. Urologe A. 33: 547-552
10. Kaye AH (1990) Photoradiation therapy of malignant brain gliomas: current concepts and further applications. In Malignant Cerebral Glioma. Apuzzo MLJ (ed.), pp. 189-202. American Association of Neurological Surgeons: Park Ridge, USA
11. Kaye AH, Morstyn G and Ashcroft RG (1985) Uptake and retention of hematoporphyrin derivate in an in vivo/vitro model of cerebral glioma. Neurosurgery 17: 883-890
12. Kaye AH, Morstyn G and Brownbill D (1987) Adjuvant high dose photoradiation therapy in the treatement of cerebral glioma: a phase 1-2 study. J Neurosurg 67: 500-505
13. Kornblith PK, Welch WC and Bradley MK (1993) The Future of Therapy for Glioblastoma. Surg Neurol 39: 538-543
14. Kostron H, Bellnier DA, Lin CW, Swartz MR and Maturza RL (1986) Distribution, retention, and phototoxicity of hematoporphyrin derivate in a rat glioma: intraneoplastic versus intraperitoneal injection. J Neurosurg 64: 768-774
15. Kostron H, Fritsch E and Grunert V (1988) Photodynamic therapy of malignant brain tumours: a phase I-II trial. Br J Neurosurg 2: 241-248
16. Kostron H, Obwegeser A and Jakober R (1996) Photodynamic therapy in neurosurgery: a review. J Photochem Photobiol B 36: 157-168
17. Kriegmair M, Baumgartner R, Knuchel R, Stepp H, Hofstadter F and Hofstetter A (1996) Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin. J Urol 155: 105-109
18. Mlkvy P, Messmann H, Pauer M, Stewart JC, Millson CE, Macrobert AJ and Brown SG (1996) Distribution and photodynamic effects of mesotetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster. Br J Cancer 73: 1473-1479
19. Muller PJ and Wilson BC (1990) Photodynamic therapy of malignant brain tumours. Can J Neurol Sci 17: 193-198
20. Obwegeser A, Ortler M, Seiwald M, Ulmer H and Kostron H (1995) Therapy of glioblastoma multiforme: a cumulative experience of 10 years. Acta Neurochir (Wien) 137: 29-33
21. Peng Q, Moan J, Ma LW and Nesland JM (1995) Uptake localization, and photodynamic effect of meso-tetra(hydroxyphenyl)porphyrin and its corresponding chlorin in normal and tumor tissue of mice bearing mammary carcinoma. Cancer Res 55: 2620-2626
22. Popovic EA, Kaye AH and Hill JS (1995) Photodynamic therapy of brain tumors. Semin Surg Oncol 11: 335-345
23. Regula J, Ravi B, Bedwell J, Macrobert AJ and Brown SG (1994) Photodynamic therapy using 5-aminolaevulinic acid for experimental pancreatic cancer prolonged animal survival. Br J Cancer 70: 248-254
24. Ris HB, Altermatt HJ, Nachbur B, Stewart JC, Wang Q, Lim CK, Bonnett R and Althaus U(1993) Effect of drug light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma. Int J Cancer 53: 141-146
25. Stummer W, Goetz C, Hassan A, Heimann A and Kempski O (1993) Kinetics of photofrin II in perifocal brain edema. Neurosurg 33: 1075-1081
26. Stummer W, Stocker S, Wagner S, Stepp H, Fritsch C, Goetz C, Goetz AE, Kiefmann W and Reulen HJ (1997) Intraoperative detection of malignant glioma by 5-ALA induced porphyrin flourescence. Neurosurgery 42: 518-525
27. Szeimies RM and Landthaler M (1995) Topical photodynamic therapy in treatment of superficial skin tumors. Hautarzt 46: 315-318
28. Van der Veen N, Van Leengoed HL and Star WM (1994) In vivo flourescence kinetics and photodynamic therapy using 5-aminolaevulinic acid-induced porphyrin: increased damage after multiple irradiations. Br J Cancer 70: 867-872
29. van Geel IP, Oppelaar H, Oussoren YG, van der Valk MA and Stewart FA (1995) Photosensitizing efficacy of MTHPC-PDT compared to photofrin-PDT in the RIF1 mouse tumour and normal skin. Int J Cancer 60: 388-394
30. Van Hillegersberg R, Hekking Weijima JM, Wilson JH, Edixhoven Bosdijk A, Kort WJ (1995) Adjuvant intraoperative photodynamic therapy diminishes the rate of local recurrence in a rat mammary tumour model. Br J Cancer 71: 733-737
31. Veenhuizen RB, Ruevekamp Helmers MC, Helmerhorst TJ, Kenemans P, Mooi WJ, Marijnissen JP and Stewart FA (1994) Intraperitoneal photodynamic therapy in the rat: comparison of toxicity profiles for photofrin and MTHPC. Int J Cancer 59: 830-836
32. Wise BL and Taxdal DR (1967) Studies of the blood brain barrier utilizing hematoporphyrin. Brain Res 4: 387-389
33. Woodburn KW, Stylli S, Hill JS, Kaye AH, Reiss JA and Phillips DR (1992) Evaluation of tumour and tissue distribution of porphyrins for use in photodynamic therapy. Br J Cancer 65: 321-328