Initial intestinal colonization in the human infant and immune homeostasis

Annals of Nutrition and Metabolism

Volumn 63, Issue , 2013, Pages 8-15

  Walker, W Allan ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Breastfeeding; Immune homeostasis; Intestinal colonization; Probiotics

Indexed keywords

PREBIOTIC AGENT; PROBIOTIC AGENT;

ADAPTIVE IMMUNITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL IMMUNITY; CELLULAR IMMUNITY; COMMENSALISM; DISEASE ASSOCIATION; DYSBIOSIS; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMORAL IMMUNITY; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; INFANCY; INFANT; INFANT NUTRITION; INFECTION PREVENTION; INNATE IMMUNITY; INTESTINE FLORA; META ANALYSIS (TOPIC); MOUTH CAVITY; NONHUMAN; ORAL TOLERANCE; PRIORITY JOURNAL; SYMBIOSIS;

ASTHMA; AUTOIMMUNE DISEASES; BIFIDOBACTERIUM; FEMALE; FERMENTATION; HOMEOSTASIS; HUMANS; IMMUNITY; INFANT FORMULA; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; INTESTINES; LACTOBACILLUS; MICROBIOTA; MILK, HUMAN; OLIGOSACCHARIDES; PREBIOTICS; PREGNANCY; PROBIOTICS;

EID: 84888191097     PISSN: 02506807     EISSN: 14219697     Source Type: Journal    
DOI: 10.1159/000354907     Document Type: Article

References (64)

1. Walker WA: Bacterial colonization, probiotics and the development of intestinal host defense. Funct Food Rev 2009; 1: 13-19.
2. Weng M, Walker WA: The role of gut microbiota in programming the immune phenotype. J Dev Orig Health Dis 2013; 4: 203-214.
3. Artis D: Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 2008; 8: 411-420.
4. Zeuthen LH, Fink LN, Frokiaer H: Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta. Immunology 2008; 123: 197-208.
5. Adlerberth I, Wold AE: Establishment of the gut microbiota in Western infants. Acta Paediatr 2009; 98: 229-238.
6. Yu LC, Wang JT, Wei SC, Ni YH: Host-microbial interactions and regulation of intestinal epithelial barrier function: from physiology to pathology. World J Gastrointest Pathophysiol 2012; 3: 27-43.
7. Renz H, Brandtzaeg P, Hornef M: The impact of perinatal immune development on mucosal homeostasis and chronic inflammation. Nat Rev Immunol 2011; 12: 9-23.
8. Gareau MG, Sherman PM, Walker WA: Probiotics and the gut microbiota in intestinal health and disease. Nat Rev Gastroenterol Hepatol 2010; 7: 503-514.
9. Molloy MJ, Bouladoux N, Belkaid Y: Intestinal microbiota: shaping local and systemic immune responses. Semin Immunol 2012; 24: 58-66.
10. Penders J, Thijs C, Vink C, Stelma FF, Snijders B, Kummeling I, den Brandt PA, Stobberingh EE: Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 2006; 118: 511-521.
11. Ley RE, Hamady M, Lozupone C, Turnbaugh PJ, Famey RR, Bircher S, Schlegel ML, Tucker TA, Schrenzel MD, Knight R, Gordon JI: Evolution of mammals and their gut microbes. Science 2008; 320: 1647.
12. Yoshioka H, Iseki K, Fujita K: Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants. Pediatrics 1983; 72: 317-321.
13. Palmer C, Bik EM, Digiulio DB, Relman DA, Brown P: Development of the human infant intestinal microbiota. PLoS One 2007; 5:e177.
14. Cotten CM, Taylor S, Stoll B, Goldberg RN, Hansen NI, Sanchez PJ, Ambalavanan N, Benjamin DK Jr, NICHD Neonatal Research Network: Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infants. Pediatrics 2009; 123: 58-66.
15. Shanahan F: Host-flora interactions in inflammatory bowel disease. Inflamm Bowel Dis 2004; 10(suppl 1):S16-S24.
16. Medzhitov R: Toll-like receptors and innate immunity. Nat Rev Immunol 2001; 1: 135-145.
17. Artis D: Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 2008; 8: 411-420.
18. Walker WA: Bacterial colonization, probiotics and the development of intestinal host defense. Funct Food Rev 2009; 1: 13-19.
19. Weng M, Walker WA: The role of gut microbiota in programming the immune phenotype. J Dev Orig Health Dis 2013; 4: 203-214.
20. Artis D: Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 2008; 8: 411-420.
21. Zeuthen LH, Fink LN, Frokiaer H: Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta. Immunology 2008; 123: 197-208.
22. Adlerberth I, Wold AE: Establishment of the gut microbiota in Western infants. Acta Paediatr 2009; 98: 229-238.
23. Yu LC, Wang JT, Wei SC, Ni YH: Host-microbial interactions and regulation of intestinal epithelial barrier function: from physiology to pathology. World J Gastrointest Pathophysiol 2012; 3: 27-43.
24. Renz H, Brandtzaeg P, Hornef M: The impact of perinatal immune development on mucosal homeostasis and chronic inflammation. Nat Rev Immunol 2011; 12: 9-23.
25. Gareau MG, Sherman PM, Walker WA: Probiotics and the gut microbiota in intestinal health and disease. Nat Rev Gastroenterol Hepatol 2010; 7: 503-514.
26. Molloy MJ, Bouladoux N, Belkaid Y: Intestinal microbiota: shaping local and systemic immune responses. Semin Immunol 2012; 24: 58-66.
27. Kaplan JL, Shi HN, Walker WA: The role of microbes in developmental immunologic programming. Pediatr Res 2011; 69: 465-472.
28. Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL: An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005; 122: 107-118.
29. Liew FY, Xu D, Brint EK, O'Neill LA: Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol 2005; 5: 446-458.
30. Macpherson AJ, Uhr T: Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 2004; 303: 1662-1665.
31. Selner JC, Merrill DA, Claman HN: Salivary immunoglobulin and albumin: development during the newborn period. J Pediatr 1968; 72: 685-689.
32. Banchereau J, Steinman RM: Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
33. Bashir ME, Louie S, Shi HN, Nagler-Anderson C: Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy. J Immunol 2004; 172: 6978-6987.
34. Spiekermann G, Walker WA: Oral tolerance and its role in clinical disease. J Pediatr Gastroenterol Nutr 2001; 32: 237-255.
35. Sudo N, Sawamura SA, Tanaka L, Aiba Y, Kubo C, Ooga Y: The requirement of intestinal flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 1997; 159: 1739-1745.
36. Karlsson MR, Kahu H, Hanson LA, Telemo E, Dahlgren UI: Neonatal colonization of rats induces immunological tolerance to bacterial antigens. Eur J Immunol 1999; 29: 109-118.
37. Yoshioka H, Iseki K, Fujita K: Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants. Pediatrics 1983; 72: 317-321.
38. Ogawa Kumiki, Ben RA, Pons S, dePaolo MIL, Fernandez LB: Volatile fatty acids, lactic acid, and pH in the stools of breast-fed and bottle-fed infants. J Pediatr Gastroenterol Nutr 1992; 15: 248-252.
39. Schwartz S, Friedberg I, Ivanov IV, Davidson LA, Goldsby JS, Dahl DB, Herman D, Wang M, Donovan SM, Chapkin RS: A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response. Genome Biol 2012; 13:r32.
40. Faith JJ, McNulty NP, Rey RE, Gordon JI: Predicting a human gut microbiota's response to diet and gnotobiotic mice. Science 2011; 33: 101.
41. De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, Massart S, Collini S, Pieraccini G, Lionetti P: Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci USA 2010; 107: 14691-14696.
42. Newburg DS, Walker WA: Protection of the neonate by the immune system of developing gut and of human milk. Pediatr Res 2007; 61: 2-8.
43. Sjogren YM, Tomicic S, Lundberg A, Bottcher MF, Bjorksten B, Sverremark-Ekstrom E, Jenmalm MC: Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses. Clin Exp Allergy 2009; 39: 1842-1851.
44. Garrido D, Kim JH, German JB, Raybould HE, Mills DA: Oligosaccharide binding proteins from Bifidobacterium longum subsp. infantis reveal a preference for host glycans. PLoS One 2011; 6:e17315.
45. Chichlowski M, De Lartigue G, German JB, Roybould HE, Mills DA: Bifidobacteria isolated from infants and cultured on human milk oligosaccharides affect intestinal epithelial function. J Pediatr Gastroenterol Nutr 2012; 55: 321-327.
46. Mazmanian SK, Round JL, Kasper DL: A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008; 453: 620-625.
47. Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG, Gordon JI: Molecular analysis of commensal host-microbial relationships in the intestine. Science 2001; 291: 881-884.
48. Lin HC, Su BH, Chen AC, Lin TW, Tsai CH, Yeh TF, Oh W: Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. Pediatrics 2005; 115: 1-4.
49. Claud EC, Lu L, Anton PM, Savidge T, Walker WA, Cherayil BJ: Developmentally regulated IkappaB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation. Proc Natl Acad Sci USA 2004; 101: 7404-7408.
50. Nanthakumar N, Fusunyan RD, Sanderson IR, Walker WA: Inflammation in the developing human intestine: a possible pathophysiologic basis for necrotizing enterocolitis. Proc Natl Acad Sci USA 2000; 97: 6043-6048.
51. Nanthakumar N, Meng D, Goldstein AM, Zhu W, Lu K, Uauy R, Llano A, Claud EC, Walker WA: The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PLoS One 2011; 6:e17776.
52. Marra F, Marra CA, Richardson K, Lynd LD, Kozyrskyj A, Patrick DA, Bowe WR, FitzGerald JM: Antibiotic use in children is associated with increased risk of asthma. Pediatrics 2009; 123: 1003-1010.
53. Kronman MP, Zaoutis TE, Haynes K, Feng R, Coffine SE: Antibiotic exposure and IBD development among children: a populationbased cohort study. Pediatrics 2012; 130:e794-e703.
54. Eggesbo M, Botten G, Stigum H, Nafstad P, Magnus P: Is delivery by cesarean section a risk factor for food allergy? J Allergy Clin Immunol 2003; 112: 420-426.
55. Kalliomaki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E: Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet 2001; 357: 1076-1079.
56. Kalliomaki M, Salminen S, Poussa T, Arvilommi H, Isolauri E: Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet 2003; 361: 1869-1871.
57. Kuitunen M, Kukkonen K, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Haahtela T, Savilahti E: Probiotics prevent IgE-associated allergy until age 5 years in cesareandelivered children but not in the total cohort. J Allergy Clin Immunol 2009; 123: 335-341.
58. Martin CR, Walker WA: Probiotics: role in pathophysiology and prevention in necrotizing enterocolitis. Semin Perinatol 2008; 32: 127-137.
59. Deshpande G, Rao S, Patole S: Probiotics prevent necrotizing enterocolitis in preterm neonates: a meta-analysis perspective. Funct Food Rev 2011; 3: 22-30.
60. Lin HC, Hsu CH, Chen HL, Chung MY, Hsu JF, Lien R, Tsao LY, Chen CH, Su BH: Oral probiotics prevent necrotizing enterocolitis in very low birth weight preterm infants: a multicenter, randomized, controlled trial. Pediatrics 2008; 122: 693-700.
61. Ganguli K, Meng D, Rautava S, Lu L, Walker WA, Nanthakumar N: Probiotics prevent necrotizing enterocolitis by modulating enterocyte genes that regulate innate immunemediated inflammation. Am J Physiol Gastrointest Liver Physiol 2013; 304:G132-G141.
62. Arslanoglu S, Moro GE, Boehm G: Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr 2007; 137: 2420-2424.
63. Fukushima Y, Kawata Y, Hara H, Terada A, Mitsuoka T: Effect of a probiotic formula on intestinal immunoglobulin A production in healthy children. Int J Food Microbiol 1998; 42: 39-44.
64. Benyacoub J, Rochat F, Saudan KY, Rochat I, Antille N, Cherbut C, von der Weid T, Schiffrin EJ, Blum S: Feeding a diet containing a fructooligosaccharide mix can enhance Salmonella vaccine efficacy in mice. J Nutr 2008; 138: 123-129.