Neonatal colonization of rats induces immunological tolerance to bacterial antigens

European Journal of Immunology

Volumn 29, Issue 1, 1999, Pages 109-118

  Karlsson, Malin R ^a   Kahu, Helena ^a   Hanson, Lars Å ^a   Telemo, Esbjörn ^a   Dahlgren, Ulf I H ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Lipopolysaccharide; Rat; Tolerance

Indexed keywords

BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G ANTIBODY; LIPOPOLYSACCHARIDE; OVALBUMIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BACTERIUM PILUS; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; ESCHERICHIA COLI; FEMALE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; INTESTINE FLORA; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; ESCHERICHIA COLI; FEMALE; HUMANS; IMMUNE TOLERANCE; INTESTINES; LIPOPOLYSACCHARIDES; LYMPH NODES; OVALBUMIN; PREGNANCY; RATS; RATS, WISTAR; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032955733     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199901)29:01<109::AID-IMMU109>3.0.CO;2-S     Document Type: Article

References (33)

1. Mata, L. and Urrutia, J., Intestinal colonization of breast-fed children in a rural area of low socio-economic level. Ann. N.Y. Acad. Sci. 1971. 176: 93-109.
2. Wold, A. E., Dahlgren, U. I. H., Hanson, L. Å., Mattsby-Baltzer, I. and Midtvedt, T., Difference between bacterial and food antigens in mucosal immunogenicity. Infect. Immun. 1989. 57: 2666-2673.
3. Mayer, L., Antigen trafficking in the intestine. Ann. N. Y. Acad. Sci. 1996. 778: 28-35.
4. Mowat, A., The regulation of immune responses to dietary protein antigens. Immunol. Today 1987. 3: 93-98.
5. Friedman, A. and Weiner, H. L., Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc. Natl. Acad. Sci. USA 1994. 91: 6688-6692.
6. Duchmann, R., Kaiser, I., Hermann, E., Mayet, W., Ewe, K. and Meyer zum Büschenfelde, K. H., Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin. Exp. Immunol. 1995. 102: 445-447.
7. Duchmann, R., Schmitt, E., Knolle, P., Meyer zum Büschenfelde, K. and Neurath, M., Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur. J. Immunol. 1996. 26: 934-938.
8. Khoo, U., Proctor, I. and Macpherson, A. J., CD4 + T cell down-regulation in human intestinal mucosa. Evidence for intestinal tolerance to luminal bacterial antigens. J. Immunol. 1997. 158: 3626-3634.
9. van den Broek, M. F., van Bruggen, M. C., Koopman, J. P., Hazenberg, M. P. and van den Berg, W. B., Gut flora induces and maintains resistance against streptococcal cell wall-induced arthritis in F344 rats. Clin. Exp. Immunol. 1992. 88: 313-317.
10. Dahlman, A., Ahlstedt, S., Hanson, L. Å., Telemo, E., Wold, A. E. and Dahlgren, U. I., Immune response against ovalbumin in rats colonized with Escherichia coli genetically manipulated to produce ovalbumin and the influence of feeding ovalbumin. Int. Arch. Allergy Appl. Immunol. 1994. 105: 381-385.
11. Asano, M., Toda, M., Sakaguchi, N. and Sakaguchi, S., Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 1996. 184: 387-396.
12. Forsthuber, T., Yip, H. C. and Lehmann, P. V., Induction of TH1 and TH2 immunity in neonatal mice [see comments]. Science 1996. 271: 1728-1730.
13. Modigliani, Y., Bandeira, A. and Coutinho, A., A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens. Immunol. Rev. 1996. 149: 155-174.
14. Ridge, J., Fuchs, E. J. and Matzinger, P., Neonatal Tolerance Revisited: Turning on Newborn T cells with Dendritic cells. Science 1996. 271: 1723-1726.
15. Sakaguchi, S., Toda, M., Asano, M., Itoh, M., Morse, S. S. and Sakaguchi, N., T cell-mediated maintenance of natural self-tolerance: its breakdown as a possible cause of varius autoimmune diseases. J. Autoimmun. 1996. 9: 211-220.
16. Hanson, D. G., Ontogeny of orally induced tolerance to soluble proteins in mice. I. Priming and tolerance in new-borns. J. Immunol. 1981. 127: 1518-1524.
17. Miller, A., Lider, O. and Weiner, H. L., Antigen-driven bystander suppression after oral administration of antigens. J. Exp. Med. 1991. 174: 791-798.
18. Prigozy, T. I., Sieling, P. A., Clemens, D., Stewart, P. L., Behar, S. M., Porcelli, S. A., Brenner, M. B., Modlin, R. L. and Kronenberg, M., The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. Immunity 1997. 6: 187-197.
19. Beckman, E. M., Porcelli, S. A., Morita, C. T., Behar, S. M., Furlong, S. T and Brenner, M. B., Recognition of a lipid antigen by CD1-restricted alpha beta + T cells [see comments]. Nature 1994. 372: 691-694.
20. Beckman, E. M. and Brenner, M. B., MHC class I-like, class II-like and cD1 molecules: distinct roles in immunity. Immunol. Today 1995. 16: 349-352.
21. Melian, A., Beckman, E. M., Porcelli, S. A. and Brenner, M. B., Antigen presentation by CD1 and MHC-encoded class I-like molecules. Curr. Opin. Immunol. 1996. 8: 82-88.
22. Bailey, M., Miller, B. G., Telemo, E., Stokes, C. R. and Bourne, F. M., Specific immunological unresponsiveness following active primary responses to proteins in the weaning diet of piglets. Int. Arch. Allergy Immunol. 1993. 101: 266-271.
23. Lindberg, A. A., The history of live bacterial vaccines. Dev. Biol. Stand. 1995. 84: 211-219.
24. Tacket, C. O., Sztein, M. B., Losonsky, G. A., Wasserman, S. S., Nataro, J. P., Edelman, R., Pickard, D., Dougan, G., Chatfield, S. N. and Levine, M. M., Safety of live oral Salmonella typhi vaccine strains with deletions in htrA and aroC aroD and immune response in humans. Infect. Immun. 1997. 65: 452-456.
25. Ryan, E. T., Butterton, J. R., Zhang, T., Baker, M. A., Stanley, S. L., Jr. and Calderwood, S. B., Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae antibody responses in mice. Infect. Immun. 1997. 65: 3118-3125.
26. Garside, P., Steel, M., Worthey, E. A., Satoskar, A., Alexander, J., Bluethmann, H., Liew, F. Y. and Mowat, A. M., T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction. J. Immunol. 1995. 154: 5649-5655.
27. Chen, Y., Inobe, J., Marks, R., Gonnella, P., Kuchroo, V. K. and Weiner, H. L., Peripheral deletion of antigen-reactive T cells in oral tolerance [published erratum appears in Nature 1995 Sep 21; 377 (6546): 257]. Nature 1995. 376: 177-180.
28. Marth, T., Strober, W. and Kelsall, B. L., High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis. J. Immunol. 1996. 157: 2348-2357.
29. Weiner, H., Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol. Today 1997. 18: 335-343.
30. Karlsson, M., Dahlgren, U. I. H., Hanson, L. Å., Telemo, E. and Lundin, S., Early expression of TGF-β and reduced enlargement of draining lymph nodes after immunisation of orally tolerised rats. Scand. J. Immunol. 1995. 41: 625.
31. Mercereau-Puijalon, O., Royal, A., Cami, B., Garapin, A., Krust, A., Gannon, F. and Kourilsky, P., Synthesis of an ovalbumin-like protein by Escherichia coli 19 K-12 harbouring a recombinant plasmid. Nature 1978. 275: 505-510.
32. Mercereau-Puijalon, O. and Kourilsky, P., Introns in the chicken ovalbumin gene prevent ovalbumin synthesis in E. coli 19 K-12. Nature 1979. 279: 647-649.
33. Westphal, O. and Jann, K., Bacterial lipopolysaccharides. Extraction with phenol-water and further application of the procedure. Methods Carbohydr. Chem. 1965. 5: 83-91.