Atomoxetine improved attention in children and adolescents with attention-deficit/hyperactivity disorder and dyslexia in a 16 week, acute, randomized, double-blind trial

Journal of Child and Adolescent Psychopharmacology

Volumn 23, Issue 9, 2013, Pages 605-613

  Wietecha, Linda ^a   Williams, David ^b   Shaywitz, Sally ^c   Shaywitz, Bennett ^c   Hooper, Stephen R ^d   Wigal, Sharon B ^e   Dunn, David ^f   McBurnett, Keith ^g  

^a Lilly USA   (United States)

^b SYNEOS HEALTH   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMOXETINE; PLACEBO;

ADHD RATING SCALE IV PARENT VERSION INVESTIGATOR CHANGES AND SCORED; ADHD RATING SCALE IV TEACHER VERSION; ADOLESCENT; AGGRESSION; ARTICLE; ATTENTION; ATTENTION DEFICIT DISORDER; CHILD; CHILD CARE; COGNITION; CONTROLLED STUDY; DECREASED APPETITE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DYSLEXIA; FATIGUE; FEMALE; HUMAN; INTERVIEW; KIDDIE SLUGGISH COGNITIVE TEMPO INTERVIEW; LIFE PARTICIPATION SCALE CHILD OR PARENT RATED VERSION; LIFE PERFORMANCE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MULTIDIMENSIONAL SELF CONCEPT SCALE; NAUSEA; PERFORMANCE; PSYCHOLOGIC TEST; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCHOOL CHILD; SCORING SYSTEM; SELF CONCEPT; SIDE EFFECT; SLUGGISH COGNITIVE TEMPO; SOMNOLENCE; THERAPY EFFECT; TREATMENT OUTCOME; UPPER ABDOMINAL PAIN; WORKING MEMORY; WORKING MEMORY TEST BATTERY FOR CHILDREN;

ADOLESCENT; ADRENERGIC UPTAKE INHIBITORS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; COGNITION; DOUBLE-BLIND METHOD; DYSLEXIA; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; PROPYLAMINES; PSYCHIATRIC STATUS RATING SCALES; SELF CONCEPT; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 84888111488     PISSN: 10445463     EISSN: 15578992     Source Type: Journal    
DOI: 10.1089/cap.2013.0054     Document Type: Article

References (32)

1. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision. Washington, DC: American Psychiatric Association; 2000
2. Barkley RA: Distinguishing sluggish cognitive tempo from attentiondeficit/ hyperactivity disorder in adults. J Abnorm Psychol 121:978- 990, 2012
3. Barkley RA, Fischer M: Predicting impairment in major life activities and occupational functioning in hyperactive children as adults: Self-reported executive function (EF) deficits versus EF tests. Dev Neuropsychol 36:137-161, 2011
4. Bracken BA: Multidimensional Self Concept Scale (MSCS) Examiners Manual. Austin, TX: PRO-ED, 1992
5. Brod M, Schmitt E, Goodwin M, Hodgkins P, Niebler G: ADHD burden of illness in older adults: a life course perspective. Qual Life Res 21:795-799, 2012
6. Carlson CL, Mann M: Sluggish cognitive tempo predicts a different pattern of impairment in the attention deficit hyperactivity disorder, predominantly inattentive type. J Clin Child Adolesc Psychol 31:123-129, 2002 (Pubitemid 37110146)
7. de Jong CG, Van De Voorde S, Roeyers H, Raymaekers R, Allen AJ, Knijff S, Verhelst H, Temmink AH, Smit LM, Rodriques-Pereira R, Vandenberghe D, van Welsen I, ter Schuren L, Al-Hakim M, Amin A, Vlasveld L, Oosterlaan J, Sergeant JA: Differential effects of atomoxetine on executive functioning and lexical decision in attention-deficit/hyperactivity disorder and reading disorder. J Child Adolesc Psychopharmacol 19:699-707, 2009
8. DuPaul G, Power T, Anastopolous A, Reid R ADHD Rating Scale-IV: Checklists, Norms, and Clinical Interpretation. New York: Guilford Publications; 1998
9. Garner AA, Marceaux JC, Mrug S, Patterson C, Hodgens B: Dimensions and correlates of attention deficit/hyperactivity disorder and sluggish cognitive tempo. J Abnorm Child Psychol 38:1097-1107, 2010
10. Germano E, Gagliano A, Curatolo P: Comorbidity of ADHD and dyslexia. Dev Neuropsychol 35:475-493, 2010
11. Hartman CA, Willcutt EG, Rhee SH, Pennington BF: The relation between sluggish cognitive tempo and DSM-IV ADHD. J Abnorm Child Psychol 32:491-503, 2004 (Pubitemid 39158508)
12. Hinshaw SP, Carte ET, Sami N, Treuting JJ, Zupan BA: Preadolescent girls with attention-deficit/hyperactivity disorder: II. Neuropsychological performance in relation to subtypes and individual classification. J Consult Clin Psychol 70:1099-1111, 2002
13. Houck G, Kendall J, Miller A, Morrell P, Wiebe G: Self-concept in children and adolescents with attention deficit hyperactivity disorder. J Pediatr Nurs 26:239-247, 2011
14. Huang-Pollock CL, Nigg JT, Carr TH: Deficient attention is hard to find: Applying the perceptual load model of selective attention to attention deficit hyperactivity disorder subtypes. J Child Psychol Psychiatry 46:1211-1218, 2005 (Pubitemid 44202679)
15. Kaufman J, Birmaher B, Brent D, Rao U, Flynn C, Moreci P, Williamson D, Ryan N: Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 36:980-988, 1997 (Pubitemid 27272932)
16. Lee S, Burns GL, Snell J, McBurnett K: Validity of the sluggish cognitive tempo symptom dimension in children: Sluggish cognitive tempo and ADHD-inattention as distinct symptom dimensions. J Abnorm Child Psychol 2013 [Epub ahead of print].
17. McBurnett K, Pfiffner LJ, Frick PJ: Symptom properties as a function of ADHD type: An argument for continued study of sluggish cognitive tempo. J Abnorm Child Psychol 29:207-213, 2001 (Pubitemid 33745806)
18. Paloyelis Y, Rijsdijk F, Wood AC, Asherson P, Kuntsi J: The genetic association between ADHD symptoms and reading difficulties: The role of inattentiveness and IQ. J Abnorm Child Psychol 38:1083- 1095, 2010
19. Penny AM, Waschbusch DA, Klein RM, Corkum P, Eskes G: Developing a measure of sluggish cognitive tempo for children: content validity, factor structure, and reliability. Psychol Assess 21:380-389, 2009
20. Pfiffner LJ, Yee Mikami A, Huang-Pollock C, Easterlin B, Zalecki C, McBurnett K: A randomized, controlled trial of integrated homeschool behavioral treatment for ADHD, predominantly inattentive type. J Am Acad Child Adolesc Psychiatry 46:1041-1050, 2007 (Pubitemid 47220686)
21. Pickering S, Gathercole S: Working Memory Test Battery for Children (WMTB-C) Manual. London: Pearson Assessment, 2001
22. Reeves CB, Palmer S, Gross AM, Simonian SJ, Taylor L, Willingham E, Mulhern RK: Brief report: Sluggish cognitive tempo among pediatric survivors of acute lymphoblastic leukemia. J Pediatr Psychol 32:1050-1054, 2007 (Pubitemid 47622300)
23. Ridley C: The experiences of nursing students with dyslexia. Nurs Stand 25:35-42, 2011
24. Sexton CC, Gelhorn H, Bell J, Classi P: The co-occurrence of reading disorder and ADHD: Epidemiology, treatment, psychosocial impact, and economic burden. J Learn Disabil 45:538-564, 2012
25. Shaywitz SE, Shaywitz BA: Paying attention to reading: The neurobiology of reading and dyslexia. Dev Psychopathol 20:1329-1349, 2008
26. Skirbekk B, Hansen BH, Oerbeck B, Kristensen H: The relationship between sluggish cognitive tempo, subtypes of attention-deficit/ hyperactivity disorder, and anxiety disorders. J Abnorm Child Psychol 39:513-525, 2011
27. Smith-Spark JH, Fawcett AJ, Nicolson RI, Fisk JE: Dyslexic students have more everyday cognitive lapses. Memory 12:174-182, 2004 (Pubitemid 38425545)
28. Sumner CR, Gathercole S, Greenbaum M, Rubin R, Williams D, Hollandbeck M, Wietecha L: Atomoxetine for the treatment of attention- deficit/hyperactivity disorder (ADHD) in children with ADHD and dyslexia. Child Adolesc Psychiatry Ment Health 3:40, 2009
29. Wahlstedt C, Bohlin G: DSM-IV-defined inattention and sluggish cognitive tempo: independent and interactive relations to neuropsychological factors and comorbidity. Child Neuropsychol 16:350-365, 2010
30. Willcutt EG, Betjemann RS, McGrath LM, Chhabildas NA, Olson RK, DeFries JC, Pennington BF: Etiology and neuropsychology of comorbidity between RD and ADHD: The case for multiple-deficit models. Cortex 46:1345-1361, 2010
31. Willcutt EG, Pennington BF, Olson RK, DeFries JC: Understanding comorbidity: A twin study of reading disability and attention-deficit/ hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 144B:709-714, 2007 (Pubitemid 47417197)
32. Yee Mikami A, Huang-Pollock CL, Pfiffner LJ, McBurnett K, Hangai D: Social skills differences among attention-deficit/hyperactivity disorder types in a chat room assessment task. J Abnorm Child Psychol 35:509-521, 2007. (Pubitemid 47174618)