Discovery of 4,6-substituted-(diaphenylamino)quinazolines as potent c-Src inhibitors

Organic and Biomolecular Chemistry

Volumn 11, Issue 48, 2013, Pages 8375-8386

  Li, Jing Ran ^a   Li, Dong Dong ^a   Fang, Fei ^a   Du, Qian Ru ^a   Lin, Lin ^a   Sun, Jian ^a   Qian, Yong ^a   Zhu, Hai Liang ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-PROLIFERATION ACTIVITIES; ENZYME ASSAYS; HUMAN TUMOR CELL LINES; INHIBITORY ACTIVITY; MOLECULAR DOCKING; SMALL MOLECULES; STRUCTURE AND ACTIVITIES; TUMOR CELL LINES;

BINDING ENERGY; BIOACTIVITY; ENZYMES;

CELL CULTURE;

ANTINEOPLASTIC AGENT; CSK TYROSINE PROTEIN KINASE; CSK TYROSINE-PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; QUINAZOLINE DERIVATIVE;

ARTICLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; HUMAN; METABOLISM; NEOPLASM; TUMOR CELL CULTURE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; NEOPLASMS; PROTEIN KINASE INHIBITORS; QUINAZOLINES; SRC-FAMILY KINASES; TUMOR CELLS, CULTURED;

EID: 84888109492     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c3ob41161c     Document Type: Article

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