7-alkyl- and 7-cycloalkyl-5-aryl-pyrrolo[2,3-d]pyrimidines - Potent inhibitors of the tyrosine kinase c-Src

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 6, 2001, Pages 849-852

  Widler, Leo ^a   Green, Jonathan ^a   Missbach, Martin ^a   Šuša, Mira ^a   Altmann, Eva ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETOPHENONE DERIVATIVE; ALPHA BROMOACETOPHENONE DERIVATIVE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE P60; PYRROLO[2,3 D]PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SPECIFICITY; MOUSE; NONHUMAN;

ALKANES; ENZYME INHIBITORS; ONCOGENE PROTEINS V-ABL; PYRIMIDINES; PYRROLES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035953047     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00079-8     Document Type: Article

References (18)