Three-dimensional quantitative structure-activity relationship studies on novel series of benzotriazine based compounds acting as Src inhibitors using CoMFA and CoMSIA

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 5, 2008, Pages 2439-2447

  Gueto, Carlos ^a   Ruiz, José L ^a   Torres, Juan E ^a   Méndez, Jefferson ^a   Vivas Reyes, Ricardo ^a  

^a UNIVERSIDAD DE CARTAGENA   (Colombia)

Author keywords

Benzotriazine; Bioinformatic; CoMFA; CoMSIA; Src inhibitors

Indexed keywords

BENZOTRIAZINE DERIVATIVE; PROTEIN TYROSINE KINASE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; HYDROPHOBICITY; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOFTWARE; SRC-FAMILY KINASES; TRIAZINES;

EID: 40749101452     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.11.053     Document Type: Article

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