Bridgehead enolate or bridgehead organolithium? DFT calculations provide insights into a difficult bridgehead substitution reaction in the synthesis of the polycyclic polyprenylated acylphloroglucinol (PPAP) nemorosone

Organic and Biomolecular Chemistry

Volumn 11, Issue 48, 2013, Pages 8458-8462

  Hayes, Christopher J ^a   Simpkins, Nigel S ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL STUDIES; DFT CALCULATION; ENOLATES; LITHIATION; METALLATION; ORGANOLITHIUMS; STRUCTURAL POSSIBILITIES;

KETONES;

SUBSTITUTION REACTIONS;

BENZOPHENONE DERIVATIVE; BRIDGED COMPOUND; LITHIUM; NEMOROSONE; PHLOROGLUCINOL;

ACYLATION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS;

ACYLATION; BENZOPHENONES; BRIDGED COMPOUNDS; LITHIUM; MODELS, MOLECULAR; PHLOROGLUCINOL;

EID: 84888099404     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c3ob41064a     Document Type: Article

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