Bridgehead lithiation-substitution of bridged ketones, lactones, lactams, and imides: Experimental observations and computational insights

Journal of the American Chemical Society

Volumn 131, Issue 23, 2009, Pages 8196-8210

  Hayes, Christopher J ^a   Simpkins, Nigel S ^a,b   Kirk, Douglas T ^a   Mitchell, Lee ^a   Baudoux, Jerome ^a   Blake, Alexander J ^a   Wilson, Claire ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

B3LYP CALCULATIONS; CARBONYL COMPOUNDS; COMPUTATIONAL STUDIES; DEPROTONATED SPECIES; ENOLATES; EXPERIMENTAL OBSERVATION; LITHIATION;

AMIDES; AMINES; CARBONYLATION;

KETONES;

BRIDGED COMPOUND; CARBONYL DERIVATIVE; IMIDE; KETONE; LACTAM; LACTONE; LITHIUM;

ACCURACY; ARTICLE; CALCULATION; CHEMICAL STRUCTURE; LABORATORY; LITHIATION; PREDICTION; PROTON TRANSPORT; SUBSTITUTION REACTION; CHEMICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; MATHEMATICAL COMPUTING;

BRIDGED COMPOUNDS; COMPUTER SIMULATION; IMIDES; KETONES; LACTAMS; LACTONES; LITHIUM; MATHEMATICAL COMPUTING; MODELS, CHEMICAL; MOLECULAR STRUCTURE;

EID: 67650519060     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9009875     Document Type: Article

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