메뉴 건너뛰기




Volumn 14, Issue 1, 2013, Pages

Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 90 INHIBITOR; HUNTINGTIN;

EID: 84888098438     PISSN: None     EISSN: 14712091     Source Type: Journal    
DOI: 10.1186/1471-2091-14-34     Document Type: Article
Times cited : (15)

References (50)
  • 2
    • 45149107487 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in Huntington's disease
    • DOI 10.1111/j.1460-9568.2008.06310.x
    • Mechanisms of neurodegeneration in Huntington's disease. Gil JM, Rego AC, Euro J Neurosci 2008 27 2803 2820 10.1111/j.1460-9568.2008.06310.x (Pubitemid 351832229)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.11 , pp. 2803-2820
    • Gil, J.M.1    Rego, A.C.2
  • 3
    • 0030897816 scopus 로고    scopus 로고
    • 180 repeat expansion and the propagation of highly expanded CAG repeats in lambda phage
    • DOI 10.1007/s004390050432
    • Identification of an HD patient with a (CAG)180 repeat expansion and the propagation of highly expanded CAG repeats in lambda phage. Sathasivam K, Amaechi I, Mangiarini L, Bates G, Hum Genet 1997 5 692 695 (Pubitemid 27192608)
    • (1997) Human Genetics , vol.99 , Issue.5 , pp. 692-695
    • Sathasivam, K.1    Amaechi, I.2    Mangiarini, L.3    Bates, G.4
  • 4
    • 44849100248 scopus 로고    scopus 로고
    • Single-step scalable-throughput molecular screening for Huntington disease
    • DOI 10.1373/clinchem.2007.096503
    • Single step scalable-throughput molecular screening for Huntington disease. Teo CRL, Wang W, Law HY, Lee CG, Chong SS, Clin Chem 2008 54 964 972 10.1373/clinchem.2007.096503 18403567 (Pubitemid 351793402)
    • (2008) Clinical Chemistry , vol.54 , Issue.6 , pp. 964-972
    • Teo, C.R.L.1    Wang, W.2    Hai, Y.L.3    Lee, C.G.4    Chong, S.S.5
  • 5
    • 84874526872 scopus 로고    scopus 로고
    • Triplet repeat primed PCR simplifies testing for Huntington disease
    • 10.1016/j.jmoldx.2012.09.005 23414820
    • Triplet repeat primed PCR simplifies testing for Huntington disease. Jama M, Millson A, Miller CE, Lyon E, J Mol Diagn 2013 15 255 262 10.1016/j.jmoldx.2012.09.005 23414820
    • (2013) J Mol Diagn , vol.15 , pp. 255-262
    • Jama, M.1    Millson, A.2    Miller, C.E.3    Lyon, E.4
  • 6
    • 35448994487 scopus 로고    scopus 로고
    • Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity
    • DOI 10.1093/hmg/ddm217
    • Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity. Atwal RS, Xia J, Pinchev D, Taylor J, Epand RM, Truant R, Hum Mol Genet 2007 16 2600 2615 10.1093/hmg/ddm217 17704510 (Pubitemid 47617727)
    • (2007) Human Molecular Genetics , vol.16 , Issue.21 , pp. 2600-2615
    • Atwal, R.S.1    Xia, J.2    Pinchev, D.3    Taylor, J.4    Epand, R.M.5    Truant, R.6
  • 7
    • 84866556522 scopus 로고    scopus 로고
    • Protein aggregates in Huntington's disease
    • 10.1016/j.expneurol.2011.12.013 22200539
    • Protein aggregates in Huntington's disease. Arrasate M, Finkbeiner S, Exp Neurol 2012 238 1 11 10.1016/j.expneurol.2011.12.013 22200539
    • (2012) Exp Neurol , vol.238 , pp. 1-11
    • Arrasate, M.1    Finkbeiner, S.2
  • 8
    • 57649187103 scopus 로고    scopus 로고
    • Mitochondria and Huntington's disease pathogenesis: Insight from genetic and chemical models
    • 10.1196/annals.1427.018 19076457
    • Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models. Browne SE, Ann NY Acad Sci 2008 1147 358 382 10.1196/annals.1427.018 19076457
    • (2008) Ann NY Acad Sci , vol.1147 , pp. 358-382
    • Browne, S.E.1
  • 9
    • 84874564486 scopus 로고    scopus 로고
    • Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin
    • 10.1371/journal.pone.0057932 23469253
    • Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin. Jin YN, Yu YV, Gundemir S, Jo C, Cui M, Tieu K, Johnson GV, Plos One 2013 8 3 57932 10.1371/journal.pone.0057932 23469253
    • (2013) Plos One , vol.8 , Issue.3 , pp. 557932
    • Jin, Y.N.1    Yu, Y.V.2    Gundemir, S.3    Jo, C.4    Cui, M.5    Tieu, K.6    Johnson, G.V.7
  • 10
    • 54849422301 scopus 로고    scopus 로고
    • Huntingtin modulates transcription, occupies gene promoters in vivo, binds directly to DNA in a polyglutamine-dependent manner
    • 10.1523/JNEUROSCI.2126-08.2008 18923047
    • Huntingtin modulates transcription, occupies gene promoters in vivo, binds directly to DNA in a polyglutamine-dependent manner. Benn CL, Sun T, Sadri-Vakili G, McFarland KN, DiRocco DP, Yohrling GJ, Clark TW, Bouzou B, Cha JH, J Neurosci 2008 28 10720 10733 10.1523/JNEUROSCI.2126-08.2008 18923047
    • (2008) J Neurosci , vol.28 , pp. 10720-10733
    • Benn, C.L.1    Sun, T.2    Sadri-Vakili, G.3    McFarland, K.N.4    Dirocco, D.P.5    Yohrling, G.J.6    Clark, T.W.7    Bouzou, B.8    Cha, J.H.9
  • 11
    • 49349090155 scopus 로고    scopus 로고
    • Huntington's disease: Degradation of mutant huntingtin by autophagy
    • 10.1111/j.1742-4658.2008.06562.x 18637946
    • Huntington's disease: degradation of mutant huntingtin by autophagy. Sarkar S, Rubinsztein DC, FEBS J 2008 275 17 4263 4270 10.1111/j.1742-4658.2008. 06562.x 18637946
    • (2008) FEBS J , vol.275 , Issue.17 , pp. 4263-4270
    • Sarkar, S.1    Rubinsztein, D.C.2
  • 12
    • 57649227693 scopus 로고    scopus 로고
    • Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
    • 10.1038/cdd.2008.110 18636076
    • Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies. Sarkar S, Ravikumar B, Floto RA, Rubinsztein DC, Cell Death Differ 2009 16 46 56 10.1038/cdd.2008.110 18636076
    • (2009) Cell Death Differ , vol.16 , pp. 46-56
    • Sarkar, S.1    Ravikumar, B.2    Floto, R.A.3    Rubinsztein, D.C.4
  • 13
    • 80555149443 scopus 로고    scopus 로고
    • Cholesterol metabolism in Huntington disease
    • 10.1038/nrneurol.2011.132 21894212
    • Cholesterol metabolism in Huntington disease. Karasinska JM, Hayden MR, Nat Rev Neurol 2011 7 561 572 10.1038/nrneurol.2011.132 21894212
    • (2011) Nat Rev Neurol , vol.7 , pp. 561-572
    • Karasinska, J.M.1    Hayden, M.R.2
  • 14
    • 0035282594 scopus 로고    scopus 로고
    • Loss of normal huntingtin function: New developments in Huntington's disease research
    • DOI 10.1016/S0166-2236(00)01721-5, PII S0166223600017215
    • Loss of normal huntingtin function: new developments in Huntington's disease research. Cattaneo E, Rigamonti D, Goffredo D, Zuccato C, Squitieri F, Sipione S, Trends Neurosci 2001 24 182 188 10.1016/S0166-2236(00)01721-5 11182459 (Pubitemid 32166824)
    • (2001) Trends in Neurosciences , vol.24 , Issue.3 , pp. 182-188
    • Cattaneo, E.1    Rigamonti, D.2    Goffredo, D.3    Zuccato, C.4    Squitieri, F.5    Sipione, S.6
  • 15
    • 33846576161 scopus 로고    scopus 로고
    • Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease
    • DOI 10.1186/1471-2202-7-80
    • Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease. Van Raamsdonk JM, Pearson J, Murphy Z, Hayden MR, Leavitt BR, BMC Neurosci 2006 7 80 10.1186/1471-2202-7-80 17147801 (Pubitemid 46178874)
    • (2006) BMC Neuroscience , vol.7 , pp. 80
    • Van Raamsdonk, J.M.1    Pearson, J.2    Murphy, Z.3    Hayden, M.R.4    Leavitt, B.R.5
  • 19
    • 77952316271 scopus 로고    scopus 로고
    • Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis
    • Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis. Becanovic K, Pouladi MA, Lim RS, Kuhn A, Pavlidis P, Luthi-Carter R, Hayden MR, Leavitt BR, Hum Mol Genet 2010 199 8 1438 1452
    • (2010) Hum Mol Genet , vol.199 , Issue.8 , pp. 1438-1452
    • Becanovic, K.1    Pouladi, M.A.2    Lim, R.S.3    Kuhn, A.4    Pavlidis, P.5    Luthi-Carter, R.6    Hayden, M.R.7    Leavitt, B.R.8
  • 22
    • 1542350108 scopus 로고    scopus 로고
    • Genetic and environmental factors in the pathogenesis of Huntington's disease
    • DOI 10.1007/s10048-003-0169-5
    • Genetic and environmental factors in the pathogenesis of Huntington's disease. Van Dellen A, Hannan AJ, Neurogenetics 2004 5 1 9 17 10.1007/s10048-003-0169-5 14745585 (Pubitemid 38297468)
    • (2004) Neurogenetics , vol.5 , Issue.1 , pp. 9-17
    • Van Dellen, A.1    Hannan, A.J.2
  • 26
    • 77955643169 scopus 로고    scopus 로고
    • Molecular mechanisms and potential therapeutical targets in Huntington's disease
    • 10.1152/physrev.00041.2009 20664076
    • Molecular mechanisms and potential therapeutical targets in Huntington's disease. Zuccato C, Valenza M, Cattaneo E, Physiol Rev 2010 90 905 981 10.1152/physrev.00041.2009 20664076
    • (2010) Physiol Rev , vol.90 , pp. 905-981
    • Zuccato, C.1    Valenza, M.2    Cattaneo, E.3
  • 29
    • 84855478434 scopus 로고    scopus 로고
    • A screen for enhancers of clearance identifies huntingtin asa heat shock protein 9 (Hsp90) client protein
    • A screen for enhancers of clearance identifies huntingtin asa heat shock protein 9 (Hsp90) client protein. Baldo B, Weiss A, Parker CN, Bibel M, Paganetti P, Kaupmann K, JBC 2011 287 1406 1414
    • (2011) JBC , vol.287 , pp. 1406-1414
    • Baldo, B.1    Weiss, A.2    Parker, C.N.3    Bibel, M.4    Paganetti, P.5    Kaupmann, K.6
  • 32
    • 73849142374 scopus 로고    scopus 로고
    • Huntington's disease: Tagged for clearance
    • 10.1038/nm0110-32 20057421
    • Huntington's disease: tagged for clearance. Krainc D, Nat Med 2010 16 1 32 3 10.1038/nm0110-32 20057421
    • (2010) Nat Med , vol.16 , Issue.1 , pp. 32-33
    • Krainc, D.1
  • 34
    • 39549109353 scopus 로고    scopus 로고
    • Huntington's disease: Progress and potential in the field
    • DOI 10.1517/13543784.16.12.1933
    • Huntington's disease: progress and potential in the field. Stack EC, Ferrante RJ, Expert Opin Investig Drugs 2007 16 1933 1953 10.1517/13543784.16. 12.1933 18042002 (Pubitemid 351403725)
    • (2007) Expert Opinion on Investigational Drugs , vol.16 , Issue.12 , pp. 1933-1953
    • Stack, E.C.1    Ferrante, R.J.2
  • 36
    • 84855922033 scopus 로고    scopus 로고
    • Pharmacologic approaches to the treatment of Huntington's disease
    • 10.1002/mds.23953 21997232
    • Pharmacologic approaches to the treatment of Huntington's disease. Venuto CS, McGarry A, Ma Q, Kieburtz K, Mov Disord 2012 27 1 31 41 10.1002/mds.23953 21997232
    • (2012) Mov Disord , vol.27 , Issue.1 , pp. 31-41
    • Venuto, C.S.1    McGarry, A.2    Ma, Q.3    Kieburtz, K.4
  • 37
    • 33744921670 scopus 로고    scopus 로고
    • Expression and characterization of full-length human huntingtin, an elongated HEAT repeat protein
    • DOI 10.1074/jbc.M511007200
    • Expression and characterization of full-length human huntingtin, an elongated HEAT repeat protein. Li W, Serpell LC, Carter WJ, Rubinsztein DC, Huntington JA, Biol Chem 2006 281 23 15916 22 10.1074/jbc.M511007200 (Pubitemid 43848484)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.23 , pp. 15916-15922
    • Li, W.1    Serpell, L.C.2    Carter, W.J.3    Rubinsztein, D.C.4    Huntington, J.A.5
  • 41
    • 80052644148 scopus 로고    scopus 로고
    • Modulation of mutant huntingtin N-terminal cleavage and its effect on aggregation and cell death
    • 10.1007/s12640-010-9227-6 21116768
    • Modulation of mutant huntingtin N-terminal cleavage and its effect on aggregation and cell death. Juenemann K, Weisse C, Reichmann D, Kaether C, Calkhoven CF, Schilling G, Neurotox Res 2011 20 120 133 10.1007/s12640-010-9227- 6 21116768
    • (2011) Neurotox Res , vol.20 , pp. 120-133
    • Juenemann, K.1    Weisse, C.2    Reichmann, D.3    Kaether, C.4    Calkhoven, C.F.5    Schilling, G.6
  • 42
    • 84859760185 scopus 로고    scopus 로고
    • Native mutant huntingtin in human brain: Evidence for prevalence of full length monomer
    • 10.1074/jbc.M111.286609
    • Native mutant huntingtin in human brain: evidence for prevalence of full length monomer. Sapp E, Valencia A, Li X, Aronin N, Kegel KB, Vonsattel JP, Young NB, Wexler N, DiFiglia M, JBC 2012 287 16 13487 99 10.1074/jbc.M111.286609
    • (2012) JBC , vol.287 , Issue.16 , pp. 13487-13499
    • Sapp, E.1    Valencia, A.2    Li, X.3    Aronin, N.4    Kegel, K.B.5    Vonsattel, J.P.6    Young, N.B.7    Wexler, N.8    Difiglia, M.9
  • 44
    • 46749157501 scopus 로고    scopus 로고
    • Full length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
    • 10.1523/JNEUROSCI.0857-08.2008 18550760
    • Full length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. Gray M, Shirasaki DI, Cepeda C, Andre VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW, J Neurosci 2008 28 24 6182 6195 10.1523/JNEUROSCI.0857-08.2008 18550760
    • (2008) J Neurosci , vol.28 , Issue.24 , pp. 6182-6195
    • Gray, M.1    Shirasaki, D.I.2    Cepeda, C.3    Andre, V.M.4    Wilburn, B.5    Lu, X.H.6    Tao, J.7    Yamazaki, I.8    Li, S.H.9    Sun, Y.E.10    Li, X.J.11    Levine, M.S.12    Yang, X.W.13
  • 45
    • 72149107077 scopus 로고    scopus 로고
    • Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice
    • 10.1016/j.neuron.2009.11.020 20064390
    • Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW, Neuron 2009 64 6 828 840 10.1016/j.neuron.2009.11.020 20064390
    • (2009) Neuron , vol.64 , Issue.6 , pp. 828-840
    • Gu, X.1    Greiner, E.R.2    Mishra, R.3    Kodali, R.4    Osmand, A.5    Finkbeiner, S.6    Steffan, J.S.7    Thompson, L.M.8    Wetzel, R.9    Yang, X.W.10
  • 46
    • 37549004790 scopus 로고    scopus 로고
    • Genetic suppression of neurodegeneration and neurotransmitter release abnormalities caused by expanded full-length huntingtin accumulating in the cytoplasm
    • 10.1016/j.neuron.2007.11.025 18184562
    • Genetic suppression of neurodegeneration and neurotransmitter release abnormalities caused by expanded full-length huntingtin accumulating in the cytoplasm. Romero E, Cha GH, Verstreken P, Ly CV, Hughes RE, Bellen HJ, Botas J, Neuron 2008 57 1 27 40 10.1016/j.neuron.2007.11.025 18184562
    • (2008) Neuron , vol.57 , Issue.1 , pp. 27-40
    • Romero, E.1    Cha, G.H.2    Verstreken, P.3    Ly, C.V.4    Hughes, R.E.5    Bellen, H.J.6    Botas, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.