Notch signaling downregulates MUC5AC expression in airway epithelial cells through hes1-dependent mechanisms

Respiration

Volumn 86, Issue 4, 2013, Pages 341-346

  Ou Yang, Hai Feng ^a   Wu, Chan Gui ^a   Qu, Shuo Yao ^a   Li, Zhi Kui ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Airway mucus hypersecretion; MUC5AC; Notch; Transcription

Indexed keywords

MUCIN 5AC; NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENE LOCUS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; MUCUS SECRETION; NONHUMAN; NOTCH INTRACELLULAR DOMAIN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; 5' UNTRANSLATED REGION; AIRWAY EPITHELIAL CELL; CELL LINE; CLARA CELL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REPORTER GENE;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; CELL LINE; DOWN-REGULATION; HOMEODOMAIN PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUCIN 5AC; PROMOTER REGIONS, GENETIC; RECEPTORS, NOTCH; RESPIRATORY MUCOSA; SEQUENCE ALIGNMENT;

EID: 84888068468     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000350647     Document Type: Article

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