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Volumn 88, Issue 12, 2013, Pages 1001-1006

Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5′-nucleotidase

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; CYTARABINE; CYTIDINE DEAMINASE; DAUNORUBICIN; DEOXYCYTIDINE KINASE; ETOPOSIDE; IDARUBICIN; MITOXANTRONE;

EID: 84888026119     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.23549     Document Type: Article
Times cited : (27)

References (39)
  • 1
    • 0036862084 scopus 로고    scopus 로고
    • The difficult problem of acute myeloid leukemia in the older adult
    • Stone RM. The difficult problem of acute myeloid leukemia in the older adult. CA 2002;52:363-371.
    • (2002) CA , vol.52 , pp. 363-371
    • Stone, R.M.1
  • 2
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties
    • Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1, 612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 1998;92:2322-2333.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 3
    • 84055218304 scopus 로고    scopus 로고
    • Acute myeloid leukemia: 2012 update on diagnosis, risk stratification, and management
    • Estey EH. Acute myeloid leukemia: 2012 update on diagnosis, risk stratification, and management. Am J Hematol 2012;87:89-99.
    • (2012) Am J Hematol , vol.87 , pp. 89-99
    • Estey, E.H.1
  • 4
    • 0034672269 scopus 로고    scopus 로고
    • Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study
    • Slovak ML, Kopecky KJ, Cassileth PA, et al. Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood 2000;96:4075-4083.
    • (2000) Blood , vol.96 , pp. 4075-4083
    • Slovak, M.L.1    Kopecky, K.J.2    Cassileth, P.A.3
  • 5
    • 33846230449 scopus 로고    scopus 로고
    • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
    • Mrozek K, Marcucci G, Paschka P, et al. Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification? Blood 2007;109:431-448.
    • (2007) Blood , vol.109 , pp. 431-448
    • Mrozek, K.1    Marcucci, G.2    Paschka, P.3
  • 6
    • 84155165116 scopus 로고    scopus 로고
    • Prognostic implications of genetic aberrations in acute myelogenous leukemia with normal cytogenetics
    • Ghanem H, Tank N, Tabbara IA. Prognostic implications of genetic aberrations in acute myelogenous leukemia with normal cytogenetics. Am J Hematol 2012;87:69-77.
    • (2012) Am J Hematol , vol.87 , pp. 69-77
    • Ghanem, H.1    Tank, N.2    Tabbara, I.A.3
  • 7
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • Schnittger S, Schoch C, Dugas M, et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 2002;100:59-66.
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3
  • 8
    • 0037409885 scopus 로고    scopus 로고
    • Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia
    • Kottaridis PD, Gale RE, Linch DC. Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia. Leuk Lymphoma 2003;44:905-913.
    • (2003) Leuk Lymphoma , vol.44 , pp. 905-913
    • Kottaridis, P.D.1    Gale, R.E.2    Linch, D.C.3
  • 9
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 ITD in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • Kottaridis PD, Gale RE, Frew ME, et al. The presence of a FLT3 ITD in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 2001;98:1752-1759.
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3
  • 10
    • 0037114829 scopus 로고    scopus 로고
    • Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: A study of the AML Study Group Ulm
    • Frohling S, Schlenk RF, Breitruck J, et al. Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: A study of the AML Study Group Ulm. Blood 2002;100:4372-4380.
    • (2002) Blood , vol.100 , pp. 4372-4380
    • Frohling, S.1    Schlenk, R.F.2    Breitruck, J.3
  • 11
    • 19944427850 scopus 로고    scopus 로고
    • Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
    • Falini B, Mecucci C, Tiacci E, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. New Engl J Med 2005;352:254-266.
    • (2005) New Engl J Med , vol.352 , pp. 254-266
    • Falini, B.1    Mecucci, C.2    Tiacci, E.3
  • 12
    • 67149119558 scopus 로고    scopus 로고
    • The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication
    • Renneville A, Boissel N, Gachard N, et al. The favorable impact of CEBPA mutations in patients with acute myeloid leukemia is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication. Blood 2009;113:5090-5093.
    • (2009) Blood , vol.113 , pp. 5090-5093
    • Renneville, A.1    Boissel, N.2    Gachard, N.3
  • 13
    • 0037400590 scopus 로고    scopus 로고
    • Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines
    • Veuger MJ, Honders MW, Spoelder HE, et al. Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines. Leuk Res 2003;27:445-453.
    • (2003) Leuk Res , vol.27 , pp. 445-453
    • Veuger, M.J.1    Honders, M.W.2    Spoelder, H.E.3
  • 14
    • 29144492798 scopus 로고    scopus 로고
    • The prognostic value of cN-II and cN-III enzymes in adult acute myeloid leukemia
    • Galmarini CM, Cros E, Thomas X, et al. The prognostic value of cN-II and cN-III enzymes in adult acute myeloid leukemia. Haematologica 2005;90:1699-1701.
    • (2005) Haematologica , vol.90 , pp. 1699-1701
    • Galmarini, C.M.1    Cros, E.2    Thomas, X.3
  • 15
    • 0037441744 scopus 로고    scopus 로고
    • Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia
    • Stam RW, den Boer ML, Meijerink JP, et al. Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia. Blood 2003;101:1270-1276.
    • (2003) Blood , vol.101 , pp. 1270-1276
    • Stam, R.W.1    den Boer, M.L.2    Meijerink, J.P.3
  • 16
    • 70649100419 scopus 로고    scopus 로고
    • Genetic factors influencing cytarabine therapy
    • Lamba JK. Genetic factors influencing cytarabine therapy. Pharmacogenomics 2009;10:1657-1674.
    • (2009) Pharmacogenomics , vol.10 , pp. 1657-1674
    • Lamba, J.K.1
  • 17
    • 67349165135 scopus 로고    scopus 로고
    • Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5′-nucleotidase II expression ratio in primary acute myeloid leukemia cells
    • Yamauchi T, Negoro E, Kishi S, et al. Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5′-nucleotidase II expression ratio in primary acute myeloid leukemia cells. Biochem Pharmacol 2009;77:1780-1786.
    • (2009) Biochem Pharmacol , vol.77 , pp. 1780-1786
    • Yamauchi, T.1    Negoro, E.2    Kishi, S.3
  • 18
    • 0038007346 scopus 로고    scopus 로고
    • Deoxycytidine kinase and cN-II nucleotidase expression in blast cells predict survival in acute myeloid leukaemia patients treated with cytarabine
    • Galmarini CM, Thomas X, Graham K, et al. Deoxycytidine kinase and cN-II nucleotidase expression in blast cells predict survival in acute myeloid leukaemia patients treated with cytarabine. Br J Haematol 2003;122:53-60.
    • (2003) Br J Haematol , vol.122 , pp. 53-60
    • Galmarini, C.M.1    Thomas, X.2    Graham, K.3
  • 19
    • 57349152158 scopus 로고    scopus 로고
    • Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53
    • Jordheim LP, Nguyen-Dumont T, Thomas X, et al. Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53. Drug Metab Dispos 2008;36:2419-2423.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2419-2423
    • Jordheim, L.P.1    Nguyen-Dumont, T.2    Thomas, X.3
  • 20
    • 0037245970 scopus 로고    scopus 로고
    • A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity
    • Yue L, Saikawa Y, Ota K, et al. A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity. Pharmacogenetics 2003;13:29-38.
    • (2003) Pharmacogenetics , vol.13 , pp. 29-38
    • Yue, L.1    Saikawa, Y.2    Ota, K.3
  • 21
    • 58149302936 scopus 로고    scopus 로고
    • Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK)
    • Kim SR, Saito Y, Maekawa K, et al. Twenty novel genetic variations and haplotype structures of the DCK gene encoding human deoxycytidine kinase (dCK). Drug Metab Pharmacokinet 2008;23:379-384.
    • (2008) Drug Metab Pharmacokinet , vol.23 , pp. 379-384
    • Kim, S.R.1    Saito, Y.2    Maekawa, K.3
  • 22
    • 70350120572 scopus 로고    scopus 로고
    • SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: Identification of CDA SNP C-451T as an independent prognostic parameter for survival
    • Mahlknecht U, Dransfeld CL, Bulut N, et al. SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: Identification of CDA SNP C-451T as an independent prognostic parameter for survival. Leukemia 2009;23:1929-1932.
    • (2009) Leukemia , vol.23 , pp. 1929-1932
    • Mahlknecht, U.1    Dransfeld, C.L.2    Bulut, N.3
  • 23
    • 46749134759 scopus 로고    scopus 로고
    • Correlation between cytidine deaminase genotype and gemcitabine deamination in blood samples
    • Giovannetti E, Laan AC, Vasile E, et al. Correlation between cytidine deaminase genotype and gemcitabine deamination in blood samples. Nucleosides Nucleotides Nucleic Acids 2008;27:720-725.
    • (2008) Nucleosides Nucleotides Nucleic Acids , vol.27 , pp. 720-725
    • Giovannetti, E.1    Laan, A.C.2    Vasile, E.3
  • 24
    • 67650938629 scopus 로고    scopus 로고
    • Results of risk-adapted therapy in acute myeloid leukaemia. A long-term population-based follow-up study
    • Wahlin A, Billstrom R, Bjor O, et al. Results of risk-adapted therapy in acute myeloid leukaemia. A long-term population-based follow-up study. Eur J Haematol 2009;83:99-107.
    • (2009) Eur J Haematol , vol.83 , pp. 99-107
    • Wahlin, A.1    Billstrom, R.2    Bjor, O.3
  • 25
    • 49249116433 scopus 로고    scopus 로고
    • ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel
    • Green H, Soderkvist P, Rosenberg P, et al. ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel. J Pharm Sci 2008;97:2045-2048.
    • (2008) J Pharm Sci , vol.97 , pp. 2045-2048
    • Green, H.1    Soderkvist, P.2    Rosenberg, P.3
  • 26
    • 41949090673 scopus 로고    scopus 로고
    • The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
    • Gale RE, Green C, Allen C, et al. The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia. Blood 2008;111:2776-2784.
    • (2008) Blood , vol.111 , pp. 2776-2784
    • Gale, R.E.1    Green, C.2    Allen, C.3
  • 27
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis. Blood 2002;99:4326-4335.
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 28
    • 0025192831 scopus 로고
    • Intracellular concentrations of anti cancer drugs in leukemic cells in vitro vs in vivo
    • Sundman-Engberg B, Tidefelt U, Liliemark J, et al. Intracellular concentrations of anti cancer drugs in leukemic cells in vitro vs in vivo. Cancer Chemother Pharmacol 1990;25:252-256.
    • (1990) Cancer Chemother Pharmacol , vol.25 , pp. 252-256
    • Sundman-Engberg, B.1    Tidefelt, U.2    Liliemark, J.3
  • 29
    • 0027269409 scopus 로고
    • Intracellular concentrations of mitoxantrone in leukemic cells in vitro vs in vivo
    • Sundman-Engberg B, Tidefelt U, Gruber A, et al. Intracellular concentrations of mitoxantrone in leukemic cells in vitro vs in vivo. Leuk Res 1993;17:347-352.
    • (1993) Leuk Res , vol.17 , pp. 347-352
    • Sundman-Engberg, B.1    Tidefelt, U.2    Gruber, A.3
  • 30
    • 0342424370 scopus 로고    scopus 로고
    • In vitro chemosensitivity testing in acute non lymphocytic leukemia using the bioluminescence ATP assay
    • Mollgard L, Tidefelt U, Sundman-Engberg B, et al. In vitro chemosensitivity testing in acute non lymphocytic leukemia using the bioluminescence ATP assay. Leuk Res 2000;24:445-452.
    • (2000) Leuk Res , vol.24 , pp. 445-452
    • Mollgard, L.1    Tidefelt, U.2    Sundman-Engberg, B.3
  • 31
    • 33644996013 scopus 로고    scopus 로고
    • Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter
    • Fitzgerald SM, Goyal RK, Osborne WR, et al. Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter. Hum Genet 2006;119:276-283.
    • (2006) Hum Genet , vol.119 , pp. 276-283
    • Fitzgerald, S.M.1    Goyal, R.K.2    Osborne, W.R.3
  • 32
    • 33645692656 scopus 로고    scopus 로고
    • Gemcitabine pharmacogenomics: Cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics
    • Gilbert JA, Salavaggione OE, Ji Y, et al. Gemcitabine pharmacogenomics: Cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics. Clin Cancer Res 2006;12:1794-1803.
    • (2006) Clin Cancer Res , vol.12 , pp. 1794-1803
    • Gilbert, J.A.1    Salavaggione, O.E.2    Ji, Y.3
  • 33
    • 70149119002 scopus 로고    scopus 로고
    • Clinical pharmacology and pharmacogenetics of gemcitabine
    • Wong A, Soo RA, Yong WP, et al. Clinical pharmacology and pharmacogenetics of gemcitabine. Drug Metab Rev 2009;41:77-88.
    • (2009) Drug Metab Rev , vol.41 , pp. 77-88
    • Wong, A.1    Soo, R.A.2    Yong, W.P.3
  • 34
    • 0031961050 scopus 로고    scopus 로고
    • Recombinant gene products of two natural variants of the human cytidine deaminase gene confer different deamination rates of cytarabine in vitro
    • Kirch HC, Schroder J, Hoppe H, et al. Recombinant gene products of two natural variants of the human cytidine deaminase gene confer different deamination rates of cytarabine in vitro. Exp Hematol 1998;26:421-425.
    • (1998) Exp Hematol , vol.26 , pp. 421-425
    • Kirch, H.C.1    Schroder, J.2    Hoppe, H.3
  • 35
    • 0038136872 scopus 로고    scopus 로고
    • Hydrolytic nucleoside and nucleotide deamination, and genetic instability: A possible link between RNA-editing enzymes and cancer?
    • Anant S, Davidson NO. Hydrolytic nucleoside and nucleotide deamination, and genetic instability: A possible link between RNA-editing enzymes and cancer? Trends Mol Med 2003;9:147-152.
    • (2003) Trends Mol Med , vol.9 , pp. 147-152
    • Anant, S.1    Davidson, N.O.2
  • 36
    • 76049125030 scopus 로고    scopus 로고
    • AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
    • Kobayashi M, Aida M, Nagaoka H, et al. AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination. Proc Natl Acad Sci USA 2009;106:22375-22380.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 22375-22380
    • Kobayashi, M.1    Aida, M.2    Nagaoka, H.3
  • 37
    • 0037420191 scopus 로고    scopus 로고
    • Inhibition of DNA methylation and reactivation of silenced genes by zebularine
    • Cheng JC, Matsen CB, Gonzales FA, et al. Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst 2003;95:399-409.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 399-409
    • Cheng, J.C.1    Matsen, C.B.2    Gonzales, F.A.3
  • 38
    • 58249133996 scopus 로고    scopus 로고
    • Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2′-deoxycytidine
    • Lemaire M, Momparler LF, Raynal NJ, et al. Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2′-deoxycytidine. Cancer Chemother Pharmacol 2009;63:411-416.
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 411-416
    • Lemaire, M.1    Momparler, L.F.2    Raynal, N.J.3
  • 39
    • 36348945304 scopus 로고    scopus 로고
    • Pharmacogenetics of deoxycytidine kinase: Identification and characterization of novel genetic variants
    • Lamba JK, Crews K, Pounds S, et al. Pharmacogenetics of deoxycytidine kinase: Identification and characterization of novel genetic variants. J Pharmacol Exp Ther 2007;323:935-945.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 935-945
    • Lamba, J.K.1    Crews, K.2    Pounds, S.3


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