Txnip contributes to impaired glucose tolerance by upregulating the expression of genes involved in hepatic gluconeogenesis in mice

Diabetologia

Volumn 56, Issue 12, 2013, Pages 2723-2732

  Jo, Seong Ho ^a   Kim, Mi Young ^a   Park, Joo Man ^a   Kim, Tae Hyun ^a   Ahn, Yong Ho ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

db db mice; G6PC; GCK; SHP; Streptozotocin; Transcriptional regulation; TXNIP

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ISOPHANE INSULIN; PYRUVIC ACID; THIOREDOXIN INTERACTING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; G6PC GENE; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTAKE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN CELL; IMPAIRED GLUCOSE TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TOLERANCE TEST; INTRAPERITONEAL GLUCOSE TOLERANCE TEST; LIPID METABOLISM; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TXNIP GENE; UPREGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CARRIER PROTEINS; CHROMATIN IMMUNOPRECIPITATION; DIABETES MELLITUS, EXPERIMENTAL; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE-6-PHOSPHATASE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; THIOREDOXINS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84888014535     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3050-6     Document Type: Article

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