Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs

International Journal of Cardiology

Volumn 169, Issue 6, 2013, Pages 394-401

  Koskinas, Konstantinos C ^a,b   Chatzizisis, Yiannis S ^a,b   Papafaklis, Michail I ^a,b   Coskun, Ahmet U ^c   Baker, Aaron B ^b   Jarolim, Petr ^a   Antoniadis, Antonios ^a   Edelman, Elazer R ^a,b   Stone, Peter H ^a   Feldman, Charles L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Northeastern University   (United States)

Author keywords

Coronary atherosclerosis; Endothelial shear stress; Histology; Hypercholesterolemia; Intravascular ultrasound

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; CHOLESTEROL; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (NADP); HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOGRAPHY; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR PARAMETERS; CELL INFILTRATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HISTOLOGY; HYPERCHOLESTEROLEMIA; INFLAMMATORY CELL; INTRAVASCULAR ULTRASOUND; LIPID STORAGE; MALE; NONHUMAN; PLAQUE VOLUME; PRIORITY JOURNAL; SHEAR STRESS; SWINE;

CORONARY ATHEROSCLEROSIS; ENDOTHELIAL SHEAR STRESS; HISTOLOGY; HYPERCHOLESTEROLEMIA; INTRAVASCULAR ULTRASOUND;

ANIMALS; COHORT STUDIES; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; ENDOTHELIUM, VASCULAR; HYPERCHOLESTEROLEMIA; MALE; PLAQUE, ATHEROSCLEROTIC; SHEAR STRENGTH; SWINE;

EID: 84888001017     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.10.021     Document Type: Article

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