Characterization of responses initiated by different Toll-like receptor 2 ligands in chicken spleen cells

Research in Veterinary Science

Volumn 95, Issue 3, 2013, Pages 919-923

  St Paul, Michael ^a,b   Paolucci, Sarah ^a   Sharif, Shayan ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Chickens; Cytokine; Pro inflammatory; TLR2; Toll like receptors

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 8; LIPOMANNAN PROTEIN; LIPOPEPTIDE; PROTEIN FSL1; PROTEIN PAM3CSK4; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RESPONSE; GENE EXPRESSION; HELPER CELL; NONHUMAN; PROTEIN DETERMINATION; PROTEIN FUNCTION; SPLEEN CELL; TH1 CELL; TH2 CELL; UPREGULATION;

GALLUS GALLUS; MAMMALIA;

CHICKENS; CYTOKINE; PRO-INFLAMMATORY; TLR2; TOLL-LIKE RECEPTORS;

ANIMALS; CHICKENS; CYTOKINES; DIGLYCERIDES; GENE EXPRESSION REGULATION; LIGANDS; LIPOPEPTIDES; LIPOPOLYSACCHARIDES; OLIGOPEPTIDES; REAL-TIME POLYMERASE CHAIN REACTION; SPLEEN; TOLL-LIKE RECEPTOR 2;

EID: 84887988729     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2013.06.025     Document Type: Article

References (32)

1. Agrawal S., Agrawal A., Doughty B., Gerwitz A., Blenis J., Van Dyke T., Pulendran B. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. Journal of Immunology 2003, 171:4984-4989.
2. Akira S., Takeda K. Toll-like receptor signalling. Nature Reviews Immunology 2004, 4:499-511.
3. Brownlie R., Allan B. Avian toll-like receptors. Cell and Tissue Research 2011, 343:121-130.
4. Dao D.N., Kremer L., Guérardel Y., Molano A., Jacobs W.R., Porcelli S.A., Briken V. Mycobacterium tuberculosis lipomannan induces apoptosis and interleukin-12 production in macrophages. Infection and Immunity 2004, 72:2067-2074.
5. Depaolo R.W., Tang F., Kim I., Han M., Levin N., Ciletti N., Lin A., Anderson D., Schneewind O., Jabri B. Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. Cell Host & Microbe 2008, 4:350-361.
6. Dillon S., Agrawal A., Van Dyke T., Landreth G., McCauley L., Koh A., Maliszewski C., Akira S., Pulendran B. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. Journal of Immunology 2004, 172:4733-4743.
7. Dillon S., Agrawal S., Banerjee K., Letterio J., Denning T.L., Oswald-Richter K., Kasprowicz D.J., Kellar K., Pare J., Van Dyke T., Ziegler S., Unutmaz D., Pulendran B. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. The Journal of Clinical Investigation 2006, 116:916-928.
8. Fukui A., Inoue N., Matsumoto M., Nomura M., Yamada K., Matsuda Y., Toyoshima K., Seya T. Molecular cloning and functional characterization of chicken toll-like receptors. A single chicken toll covers multiple molecular patterns. The Journal of Biological Chemistry 2001, 276:47143-47149.
9. Higuchi M., Matsuo A., Shingai M., Shida K., Ishii A., Funami K., Suzuki Y., Oshiumi H., Matsumoto M., Seya T. Combinational recognition of bacterial lipoproteins and peptidoglycan by chicken Toll-like receptor 2 subfamily. Developmental and Comparative Immunology 2008, 32:147-155.
10. Ito T., Hasegawa A., Hosokawa H., Yamashita M., Motohashi S., Naka T., Okamoto Y., Fujita Y., Ishii Y., Taniguchi M., Yano I., Nakayama T. Human Th1 differentiation induced by lipoarabinomannan/lipomannan from Mycobacterium bovis BCG Tokyo-172. International Immunology 2008, 20:849-860.
11. Jenkins K.A., Lowenthal J.W., Kimpton W., Bean A.G.D. The in vitro and in ovo responses of chickens to TLR9 subfamily ligands. Developmental & Comparative Immunology 2009, 33:660-667.
12. Keestra A.M., De Zoete M.R., Van Aubel R.A.M.H., Van Putten J.P.M. The central leucine-rich repeat region of chicken TLR16 dictates unique ligand specificity and species-specific interaction with TLR2. Journal of Immunology 2007, 178:7110-7119.
13. Kiura K., Kataoka H., Yasuda M., Inoue N., Shibata K. The diacylated lipopeptide FSL-1 induces TLR2-mediated Th2 responses. FEMS Immunology and Medical Microbiology 2006, 48:44-55.
14. Kogut M.H., Iqbal M., He H., Philbin V., Kaiser P., Smith A. Expression and function of Toll-like receptors in chicken heterophils. Developmental and Comparative Immunology 2005, 29:791-807.
15. Krug A., Rothenfusser S., Hornung V., Jahrsdörfer B., Blackwell S., Ballas Z.K., Endres S., Krieg A.M., Hartmann G. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. European Journal of Immunology 2001, 31:2154-2163.
16. Laing K.J., Purcell M.K., Winton J.R., Hansen J.D. A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish. BMC Evolutionary Biology 2008, 8:42.
17. Long E.M., Millen B., Kubes P., Robbins S.M. Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligands. PloS one 2009, 4:e5601.
18. Medzhitov R. Toll-like receptors and innate immunity. Nature Reviews Immunology 2001, 1:135-145.
19. Nerren J.R., Kogut M.H. The selective Dectin-1 agonist, curdlan, induces an oxidative burst response in chicken heterophils and peripheral blood mononuclear cells. Veterinary Immunology and Immunopathology 2009, 127:162-166.
20. Oberg H.-H., Ly T.T.H., Ussat S., Meyer T., Kabelitz D., Wesch D. Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands. Journal of Immunology 2010, 184:4733-4740.
21. Patel B.A., Gomis S., Dar A., Willson P.J., Babiuk L.A., Potter A., Mutwiri G., Tikoo S.K. Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks. Developmental and Comparative Immunology 2008, 32:1041-1049.
22. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Research 2001, 29:e45.
23. St.Paul M., Mallick A.I., Haq K., Orouji S., Abdul-Careem M.F., Sharif S. In vivo administration of ligands for chicken toll-like receptors 4 and 21 induces the expression of immune system genes in the spleen. Veterinary Immunology and Immunopathology 2011, 144:228-237.
24. St.Paul M., Mallick A.I., Read L.R., Villanueva A.I., Parvizi P., Abdul-Careem M.F., Nagy E., Sharif S. Prophylactic treatment with Toll-like receptor ligands enhances host immunity to avian influenza virus in chickens. Vaccine 2012, 30:4524-4531.
25. St.Paul M., Paolucci S., Barjesteh N., Wood R.D., Schat K.A., Sharif S. Characterization of chicken thrombocyte responses to Toll-like receptor ligands. PloS one 2012, 7:e43381.
26. St.Paul M., Paolucci S., Sharif S. Treatment with ligands for Toll-like receptors 2 and 5 induces a mixed T-helper 1- and 2-like response in chicken splenocytes. Journal of Interferon & Cytokine Research 2012, 32:592-598.
27. Swaggerty C.L., Ferro P.J., Pevzner I.Y., Kogut M.H. Heterophils are associated with resistance to systemic Salmonella enteritidis infections in genetically distinct chicken lines. FEMS Immunology and Medical Microbiology 2005, 43:149-154.
28. Takeuchi O., Kawai T., Mühlradt P.F., Morr M., Radolf J.D., Zychlinsky A., Takeda K., Akira S. Discrimination of bacterial lipoproteins by Toll-like receptor 6. International Immunology 2001, 13:933-940.
29. Tapping R.I., Tobias P.S. Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling. Journal of Endotoxin Research 2003, 9:264-268.
30. Temperley N.D., Berlin S., Paton I.R., Griffin D.K., Burt D.W. Evolution of the chicken Toll-like receptor gene family: a story of gene gain and gene loss. BMC Genomics 2008, 9:62.
31. Watanabe T., Kitani A., Murray P.J., Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nature Immunology 2004, 5:800-808.
32. Wetzler L.M. The role of Toll-like receptor 2 in microbial disease and immunity. Vaccine 2003, 21:S55-S60.