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Volumn 65, Issue 12, 2013, Pages 1726-1735

Berberis aetnensis and B. libanotica: A comparative study on the chemical composition, inhibitory effect on key enzymes linked to Alzheimer's disease and antioxidant activity

Author keywords

alkaloids; anticholinesterase activity; antioxidant activity; Berberis aetnensis; Berberis libanotica

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 5 EICOSENE; 9,12 OCTADECADIEN 1 OL; ACETYLCHOLINESTERASE; ALKALOID; ANTIOXIDANT; ASCORBIC ACID; BERBERINE; BERBERIS AETNENSIS EXTRACT; BERBERIS LIBANOTICA EXTRACT; BETA CAROTENE; CAMPESTEROL; CARVACROL; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CYCLODODECENE; CYCLOEUCALENOL; GALLIC ACID PROPYL ESTER; HEXANE; METHANOL; MYRISTIC ACID; PALMATINE; PALMITIC ACID; PLANT EXTRACT; STIGMAST 4 EN 3 ONE; STIGMAST 4,22 DIEN 3 ONE; STIGMAST 4,22 DIENE; STIGMASTEROL; THYMOL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84887942949     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12172     Document Type: Article
Times cited : (36)

References (48)
  • 1
    • 0030268371 scopus 로고    scopus 로고
    • Study of the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids
    • Ivanovska N, Philipov S,. Study of the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids. Int J Immunopharmacol 1996; 18: 553-561.
    • (1996) Int J Immunopharmacol , vol.18 , pp. 553-561
    • Ivanovska, N.1    Philipov, S.2
  • 2
    • 0038649070 scopus 로고    scopus 로고
    • Berberis aetnensis C. Presl. Extracts: Antimicrobial properties and interaction with ciprofloxacin
    • et al.
    • Musumeci R, et al. Berberis aetnensis C. Presl. extracts: antimicrobial properties and interaction with ciprofloxacin. Int J Antimicrob Agents 2003; 22: 48-53.
    • (2003) Int J Antimicrob Agents , vol.22 , pp. 48-53
    • Musumeci, R.1
  • 3
    • 0002258030 scopus 로고    scopus 로고
    • Berberine: Therapeutic potential of an alkaloid found in several medicinal plants
    • Birdsall TC, Kelly GS,. Berberine: therapeutic potential of an alkaloid found in several medicinal plants. Altern Med Rev 1997; 2: 94-103.
    • (1997) Altern Med Rev , vol.2 , pp. 94-103
    • Birdsall, T.C.1    Kelly, G.S.2
  • 5
    • 48749086425 scopus 로고    scopus 로고
    • Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)
    • et al.
    • Tomosaka H, et al. Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry). Phytother Res 2008; 22: 979-981.
    • (2008) Phytother Res , vol.22 , pp. 979-981
    • Tomosaka, H.1
  • 6
    • 34250360970 scopus 로고    scopus 로고
    • Wound healing activity of root extracts of Berberis lyceum Royle in rats
    • et al.
    • Asif A, et al. Wound healing activity of root extracts of Berberis lyceum Royle in rats. Phytother Res 2007; 21: 589-591.
    • (2007) Phytother Res , vol.21 , pp. 589-591
    • Asif, A.1
  • 7
    • 33846707523 scopus 로고    scopus 로고
    • Activity of Berberis aetnensis root extracts on Candida strains
    • et al.
    • Iauk L, et al. Activity of Berberis aetnensis root extracts on Candida strains. Fitoterapia 2007; 78: 159-161.
    • (2007) Fitoterapia , vol.78 , pp. 159-161
    • Iauk, L.1
  • 8
    • 79957868177 scopus 로고    scopus 로고
    • Effect of berberine and Berberis aetnensis C. Presl. Alkaloid extract on glutamate-evoked tissue transglutaminase up-regulation in astroglial cell cultures
    • et al.
    • Campisi A, et al. Effect of berberine and Berberis aetnensis C. Presl. alkaloid extract on glutamate-evoked tissue transglutaminase up-regulation in astroglial cell cultures. Phytother Res 2011; 25: 816-820.
    • (2011) Phytother Res , vol.25 , pp. 816-820
    • Campisi, A.1
  • 9
    • 84871797879 scopus 로고    scopus 로고
    • The ethanol fraction from the stem of Berberis libanotica inhibits the viability of adult T cell leukemia
    • et al.
    • Esseily F, et al. The ethanol fraction from the stem of Berberis libanotica inhibits the viability of adult T cell leukemia. Minerva Biotecnol 2012; 24: 129-133.
    • (2012) Minerva Biotecnol , vol.24 , pp. 129-133
    • Esseily, F.1
  • 10
    • 33645542616 scopus 로고    scopus 로고
    • Berberry extract reduces neuronal damage and N-methyl-D-aspartate receptor 1 immunoreactivity in the gerbil hippocampus after transient forebrain ischemia
    • et al.
    • Yoo KY, et al. Berberry extract reduces neuronal damage and N-methyl-D-aspartate receptor 1 immunoreactivity in the gerbil hippocampus after transient forebrain ischemia. Biol Pharm Bull 2006; 29: 623-628.
    • (2006) Biol Pharm Bull , vol.29 , pp. 623-628
    • Yoo, K.Y.1
  • 11
    • 80054777175 scopus 로고    scopus 로고
    • The therapeutic potential of Berberis darwinii stem-bark: Quantification of berberine and in vitro evidence for Alzheimer's disease therapy
    • Habtemariam S,. The therapeutic potential of Berberis darwinii stem-bark: quantification of berberine and in vitro evidence for Alzheimer's disease therapy. Nat Prod Commun 2011; 6: 1089-1090.
    • (2011) Nat Prod Commun , vol.6 , pp. 1089-1090
    • Habtemariam, S.1
  • 12
    • 0037184696 scopus 로고    scopus 로고
    • A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species
    • et al.
    • Küpeli E, et al. A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sci 2002; 72: 645-657.
    • (2002) Life Sci , vol.72 , pp. 645-657
    • Küpeli, E.1
  • 13
    • 34547484479 scopus 로고    scopus 로고
    • Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride
    • Kulkarni SK, Dhir A,. Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride. Eur J Pharmacol 2007; 569: 77-83.
    • (2007) Eur J Pharmacol , vol.569 , pp. 77-83
    • Kulkarni, S.K.1    Dhir, A.2
  • 14
    • 0041309915 scopus 로고    scopus 로고
    • Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by a Coptidis rhizoma extract and protoberberine alkaloids
    • et al.
    • Shigeta K, et al. Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by a Coptidis rhizoma extract and protoberberine alkaloids. Biosci Biotechnol Biochem 2002; 66: 2491-2494.
    • (2002) Biosci Biotechnol Biochem , vol.66 , pp. 2491-2494
    • Shigeta, K.1
  • 15
    • 59949093367 scopus 로고    scopus 로고
    • Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: Involvement of B-cell lymphoma 2 phosphorylation suppression
    • et al.
    • Cui HS, et al. Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression. Biol Pharm Bull 2009; 32: 79-85.
    • (2009) Biol Pharm Bull , vol.32 , pp. 79-85
    • Cui, H.S.1
  • 16
    • 16644385507 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa
    • et al.
    • Kim DK, et al. Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Arch Pharm Res 2004; 27: 1127-1131.
    • (2004) Arch Pharm Res , vol.27 , pp. 1127-1131
    • Kim, D.K.1
  • 17
    • 0036993145 scopus 로고    scopus 로고
    • Butyrylcholinesterase: An important new target in Alzheimer's disease therapy
    • et al.
    • Greig NH, et al. Butyrylcholinesterase: an important new target in Alzheimer's disease therapy. Int Psychogeriatr 2002; 14: 77-91.
    • (2002) Int Psychogeriatr , vol.14 , pp. 77-91
    • Greig, N.H.1
  • 18
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow CW,. A radical hypothesis for neurodegeneration. Trends Neurosci 1993; 16: 439-444.
    • (1993) Trends Neurosci , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 19
    • 0028181782 scopus 로고
    • Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease
    • et al.
    • Palmer AM, et al. Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease. Brain Res 1994; 645: 338-342.
    • (1994) Brain Res , vol.645 , pp. 338-342
    • Palmer, A.M.1
  • 20
    • 0028178837 scopus 로고
    • β-amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: Implications to Alzheimer's disease
    • et al.
    • Butterfield DA, et al. β-amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem Biophys Res Commun 1994; 200: 710-715.
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 710-715
    • Butterfield, D.A.1
  • 21
    • 0000362009 scopus 로고
    • Carbon-13 NMR assignments of berberine and sanguinarine
    • et al.
    • Blaskò G, et al. Carbon-13 NMR assignments of berberine and sanguinarine. Heterocycles 1988; 27: 911-916.
    • (1988) Heterocycles , vol.27 , pp. 911-916
    • Blaskò, G.1
  • 22
    • 0032919158 scopus 로고    scopus 로고
    • A 7,8-dihydro-8-hydroxypalmatine from Enantia clorantha
    • et al.
    • Wafo P, et al. A 7,8-dihydro-8-hydroxypalmatine from Enantia clorantha. Phytochemistry 1999; 50: 279-281.
    • (1999) Phytochemistry , vol.50 , pp. 279-281
    • Wafo, P.1
  • 23
    • 33845898831 scopus 로고    scopus 로고
    • Quaternary protoberberine alkaloids
    • et al.
    • Grycovà L, et al. Quaternary protoberberine alkaloids. Phytochemistry 2007; 68: 150-175.
    • (2007) Phytochemistry , vol.68 , pp. 150-175
    • Grycovà, L.1
  • 24
    • 67349276651 scopus 로고    scopus 로고
    • Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides v Brig. (Apiaceae)
    • et al.
    • Menichini F, et al. Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae). Fitoterapia 2009; 80: 297-300.
    • (2009) Fitoterapia , vol.80 , pp. 297-300
    • Menichini, F.1
  • 25
    • 84855582549 scopus 로고    scopus 로고
    • Comparative chemical composition and antioxidant activity of Calamintha nepeta (L.) Savi subsp. Glandulosa (Req.) Nyman and Calamintha grandiflora (L.) Moench (Labiatae)
    • et al.
    • Marrelli M, et al. Comparative chemical composition and antioxidant activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Nyman and Calamintha grandiflora (L.) Moench (Labiatae). Nat Prod Res 2012; 26: 91-97.
    • (2012) Nat Prod Res , vol.26 , pp. 91-97
    • Marrelli, M.1
  • 26
    • 79952713687 scopus 로고    scopus 로고
    • Correlation between environmental factors, chemical composition, and antioxidative properties of caper species growing wild in Calabria (South Italy)
    • et al.
    • Conforti F, et al. Correlation between environmental factors, chemical composition, and antioxidative properties of caper species growing wild in Calabria (South Italy). Chem Biodivers 2011; 8: 518-531.
    • (2011) Chem Biodivers , vol.8 , pp. 518-531
    • Conforti, F.1
  • 27
    • 77955052585 scopus 로고    scopus 로고
    • Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat
    • et al.
    • Zovko Končic̈ M, et al. Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. Food Chem Toxicol 2010; 48: 2176-2180.
    • (2010) Food Chem Toxicol , vol.48 , pp. 2176-2180
    • Zovko Končic̈, M.1
  • 28
    • 77954103318 scopus 로고    scopus 로고
    • A comparative study on the antioxidant activity of methanol extracts of Acacia nilotica and Berberis chitria
    • et al.
    • Agrawal S, et al. A comparative study on the antioxidant activity of methanol extracts of Acacia nilotica and Berberis chitria. Adv in Nat Appl Sci 2010; 4: 78-84.
    • (2010) Adv in Nat Appl Sci , vol.4 , pp. 78-84
    • Agrawal, S.1
  • 29
    • 0034022847 scopus 로고    scopus 로고
    • Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity
    • et al.
    • Nostro A, et al. Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity. Lett Appl Microbiol 2001; 30: 379-384.
    • (2001) Lett Appl Microbiol , vol.30 , pp. 379-384
    • Nostro, A.1
  • 30
    • 76649117418 scopus 로고    scopus 로고
    • Habitat-dependent variations in berberine content of Berberis asiatica Roxb. Ex. DC. in Kumaon, Western Himalaya
    • et al.
    • Andola HC, et al. Habitat-dependent variations in berberine content of Berberis asiatica Roxb. ex. DC. in Kumaon, Western Himalaya. Chem Biodivers 2010; 7: 415-420.
    • (2010) Chem Biodivers , vol.7 , pp. 415-420
    • Andola, H.C.1
  • 31
    • 3342906269 scopus 로고    scopus 로고
    • Berberis alkaloids. XLI. Alkaloids from leaves of cultivated Berberis oblonga
    • et al.
    • Khamidov II, et al. Berberis alkaloids. XLI. Alkaloids from leaves of cultivated Berberis oblonga. Chem Nat Comp 2003; 39: 407.
    • (2003) Chem Nat Comp , vol.39 , pp. 407
    • Khamidov, I.I.1
  • 32
    • 84872724395 scopus 로고    scopus 로고
    • Berberine and its derivatives: A patent review (2009-2012)
    • Singh IP, Mahajan S,. Berberine and its derivatives: a patent review (2009-2012). Expert Opin Ther Pat 2013; 23: 215-231.
    • (2013) Expert Opin Ther Pat , vol.23 , pp. 215-231
    • Singh, I.P.1    Mahajan, S.2
  • 33
    • 45849090306 scopus 로고    scopus 로고
    • Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: An update
    • et al.
    • Loizzo MR, et al. Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: an update. Curr Med Chem 2008; 15: 1209-1228.
    • (2008) Curr Med Chem , vol.15 , pp. 1209-1228
    • Loizzo, M.R.1
  • 34
    • 80052157539 scopus 로고    scopus 로고
    • Acetylcholinesterase and Butyrylcholinesterase inhibitory activities of Berberis vulgaris
    • et al.
    • Kolář D, et al. Acetylcholinesterase and Butyrylcholinesterase inhibitory activities of Berberis vulgaris. Phytopharmacology 2010; 1: 7-11.
    • (2010) Phytopharmacology , vol.1 , pp. 7-11
    • Kolář, D.1
  • 35
    • 80054055026 scopus 로고    scopus 로고
    • Advances in structural modifications and biological activities of berberine: An active compound in traditional Chinese medicine
    • et al.
    • Huang ZJ, et al. Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine. Mini Rev Med Chem 2011; 11: 1122-1129.
    • (2011) Mini Rev Med Chem , vol.11 , pp. 1122-1129
    • Huang, Z.J.1
  • 36
    • 0032985993 scopus 로고    scopus 로고
    • Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells
    • et al.
    • Fukuda K, et al. Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells. J Ethnopharmacol 1999; 66: 227-233.
    • (1999) J Ethnopharmacol , vol.66 , pp. 227-233
    • Fukuda, K.1
  • 37
    • 0037245022 scopus 로고    scopus 로고
    • Inhibition of tumor-induced angiogenesis and matrix-metalloproteinase expression in confrontation cultures of embryoid bodies and tumor spheroids by plant ingredients used in traditional Chinese medicine
    • et al.
    • Wartenberg M, et al. Inhibition of tumor-induced angiogenesis and matrix-metalloproteinase expression in confrontation cultures of embryoid bodies and tumor spheroids by plant ingredients used in traditional Chinese medicine. Lab Invest 2003; 83: 87-98.
    • (2003) Lab Invest , vol.83 , pp. 87-98
    • Wartenberg, M.1
  • 38
    • 64249131013 scopus 로고    scopus 로고
    • Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats
    • Singh J, Kakkar P,. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol 2009; 123: 22-26.
    • (2009) J Ethnopharmacol , vol.123 , pp. 22-26
    • Singh, J.1    Kakkar, P.2
  • 39
    • 80052252471 scopus 로고    scopus 로고
    • Berberine: A potential multipotent natural product to combat Alzheimer's disease
    • Ji HF, Shen L,. Berberine: a potential multipotent natural product to combat Alzheimer's disease. Molecules 2011; 16: 6732-6740.
    • (2011) Molecules , vol.16 , pp. 6732-6740
    • Ji, H.F.1    Shen, L.2
  • 40
    • 85171742657 scopus 로고    scopus 로고
    • An acetylcholinesterase inhibitor isolated from Corydalis tuber and its mode of action
    • et al.
    • Hwang SY, et al. An acetylcholinesterase inhibitor isolated from Corydalis tuber and its mode of action. Korean J Pharmacogn 1996; 27: 91-95.
    • (1996) Korean J Pharmacogn , vol.27 , pp. 91-95
    • Hwang, S.Y.1
  • 41
    • 80053268387 scopus 로고    scopus 로고
    • Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds
    • et al.
    • Aazza S, et al. Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds. Molecules 2011; 16: 7672-7690.
    • (2011) Molecules , vol.16 , pp. 7672-7690
    • Aazza, S.1
  • 42
    • 51649097642 scopus 로고    scopus 로고
    • Activity of essential oils and individual components against acetyl- and butyrylcholinesterase
    • et al.
    • Orhan I, et al. Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z Naturforsch 2008; 63c: 547-553.
    • (2008) Z Naturforsch , vol.63 C , pp. 547-553
    • Orhan, I.1
  • 43
    • 34447279020 scopus 로고    scopus 로고
    • Damage to lipids, proteins, DNA and RNA in mild cognitive impairment
    • Marksberry WR, Lovell MA,. Damage to lipids, proteins, DNA and RNA in mild cognitive impairment. Arch Neurol 2007; 64: 954-956.
    • (2007) Arch Neurol , vol.64 , pp. 954-956
    • Marksberry, W.R.1    Lovell, M.A.2
  • 44
    • 0035570942 scopus 로고    scopus 로고
    • Free radical oxidative damage and Alzheimer's disease
    • Tuppo EE, Forman LJ,. Free radical oxidative damage and Alzheimer's disease. J Am Osteopath Assoc 2001; 101: S11-S15.
    • (2001) J Am Osteopath Assoc , vol.101
    • Tuppo, E.E.1    Forman, L.J.2
  • 45
    • 33745712378 scopus 로고    scopus 로고
    • Antioxidant and possible anti-inflammatory potential of selected medicinal plants prescribed in the Indian traditional system of medicine
    • Gacche RN, Dhole NA,. Antioxidant and possible anti-inflammatory potential of selected medicinal plants prescribed in the Indian traditional system of medicine. Pharm Biol 2006; 44: 389-395.
    • (2006) Pharm Biol , vol.44 , pp. 389-395
    • Gacche, R.N.1    Dhole, N.A.2
  • 46
    • 33646397841 scopus 로고    scopus 로고
    • Cytotoxic effect of Berberis vulgaris fruit extract on the proliferation of human liver cancer line (HepG2) and its antioxidant properties
    • et al.
    • Hanachi P, et al. Cytotoxic effect of Berberis vulgaris fruit extract on the proliferation of human liver cancer line (HepG2) and its antioxidant properties. Int J Cancer Res 2006; 2: 1-9.
    • (2006) Int J Cancer Res , vol.2 , pp. 1-9
    • Hanachi, P.1
  • 47
    • 23844525962 scopus 로고    scopus 로고
    • Understanding local Mediterranean diets: A multidisciplinary pharmacological and ethnobotanical approach
    • et al.
    • Heinrich M, et al. Understanding local Mediterranean diets: a multidisciplinary pharmacological and ethnobotanical approach. Pharmacol Res 2005; 52: 353-366.
    • (2005) Pharmacol Res , vol.52 , pp. 353-366
    • Heinrich, M.1
  • 48
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell B,. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 2001; 18: 685-716.
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1


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