Treatment with anticancer agents induces dysregulation of specific wnt signaling pathways in human ovarian luteinized granulosa cells in vitro

Toxicological Sciences

Volumn 136, Issue 1, 2013, Pages 183-192

  Sanchez, Ana Maria ^a   Giorgione, Veronica ^a   Viganò, Paola ^a   Papaleo, Enrico ^a   Candiani, Massimo ^a   Mangili, Giorgia ^a   Panina Bordignon, Paola ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Chemotherapy; Granulosa cells; Reproductive toxicity

Indexed keywords

BETA CATENIN; CISPLATIN; DOXORUBICIN; ESTROGEN RECEPTOR BETA; FOLLICLE STIMULATING HORMONE RECEPTOR; HORMONE RECEPTOR; LITHIUM CHLORIDE; PACLITAXEL; UNCLASSIFIED DRUG; WNT3 PROTEIN; WNT4 PROTEIN;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GRANULOSA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LUTEINIZATION; LUTEINIZED GRANULOSA CELL; MAJOR CLINICAL STUDY; OVARY FOLLICLE DEVELOPMENT; OVULATION; PROTEIN EXPRESSION; UPREGULATION; WNT SIGNALING PATHWAY;

CHEMOTHERAPY; GRANULOSA CELLS.; REPRODUCTIVE TOXICITY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CISPLATIN; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DOXORUBICIN; ESTROGEN RECEPTOR BETA; FEMALE; GRANULOSA CELLS; HUMANS; LITHIUM CHLORIDE; LUTEINIZATION; PACLITAXEL; RECEPTORS, FSH; WNT SIGNALING PATHWAY; WNT3 PROTEIN; WNT4 PROTEIN;

EID: 84887915052     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft175     Document Type: Article

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