The effects of radiotherapy and chemotherapy on female reproduction

Human Reproduction Update

Volumn 7, Issue 6, 2001, Pages 535-543

  Meirow, D ^a   Nugent, D ^b  

^a RABIN MEDICAL CENTER   (Israel)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Bone marrow transplantation; Chemotherapy; Fertility; Ovarian transposition; Radiotherapy

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE; ANTIINFECTIVE AGENT; ANTIMETABOLITE; BLEOMYCIN; BUSULFAN; CHLORAMBUCIL; CHLORMETHINE; CYCLOPHOSPHAMIDE; DACARBAZINE; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; GONADORELIN AGONIST; METHOTREXATE; PREDNISOLONE; PREDNISONE; PROCARBAZINE; SPHINGOSINE 1 PHOSPHATE; VINBLASTINE; VINCRISTINE; VINCRISTINE SULFATE;

ADOLESCENT; ADULT; AGE; ANEUPLOIDY; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CELL DESTRUCTION; CLINICAL PROTOCOL; CONTROLLED STUDY; CRYOPRESERVATION; DOWN REGULATION; DRUG EXPOSURE; EARLY MENOPAUSE; EMBRYO; FEMALE; FEMALE GENITAL SYSTEM; FEMALE INFERTILITY; FEMALE STERILIZATION; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; HYPOPHYSIS; MAJOR CLINICAL STUDY; MEDICAL DECISION MAKING; MEDICAL LITERATURE; OVARY CANCER; OVARY DISEASE; OVARY FOLLICLE; PHYSICIAN; PRIORITY JOURNAL; PROBABILITY; PROTECTION; PUBLICATION; RADIATION DOSE; RADIATION EXPOSURE; REGULATORY MECHANISM; REVIEW; RISK ASSESSMENT; SIGNAL TRANSDUCTION; SURVIVAL TIME;

ADOLESCENT; ADULT; AGE FACTORS; CHILD; DRUG THERAPY; FEMALE; HUMANS; INFERTILITY; NEOPLASMS; OVARY; RADIOTHERAPY;

EID: 0035174750     PISSN: 13554786     EISSN: None     Source Type: Journal    
DOI: 10.1093/humupd/7.6.535     Document Type: Article

References (56)

1. Mechanism and management of treatment related gonadal failure in recipients of high dose chemotherapy
2. Reproductive performance of female rats treated with cyclophosphamide and/or LHRH agonist
3. Luteinizing hormone-releasing hormone agonist inhibits cyclophosphamide-induced ovarian follicular depletion in rhesus monkeys
4. Is radiation-induced ovarian failure in rhesus monkeys preventable by luteinizing hormone-releasing hormone agonists?: Preliminary observations
5. Ovarian and uterine characteristics after total body irradiation in childhood and adolescence: Response to sex steroid replacement
6. Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer
7. Ovarian rescue/protection from chemotherapeutic agents (1)
8. Preservation of fertility and ovarian function and minimizing gonadotoxicity in young women with systemic lupus erythematosus treated by chemotherapy
9. Long-term gonadal toxicity after therapy for Hodgkin's and non-Hodgkin's lymphoma
10. Cancer statistics 1994
11. Risk for sustained amenorrhea in patients with systemic lupus erythematosus receiving intermittent pulse cyclophosphamide therapy
12. Treatment of early-stage Hodgkin's disease with four cycles of ABVD followed by adjuvant radiotherapy: Analysis of efficacy and long-term toxicity
13. Effects of treatment on fertility in long-term survivors of childhood of adolescent cancer
14. Early menopause in long-term survivors of cancer during adolescence
15. Cytotoxic-induced ovarian failure in Hodgkin's disease. I. Hormone function
16. Early menopause and infertility in females after treatment for childhood cancer diagnosed in 1964-1988 in Ontario, Canada
17. Ovarian transposition by laparoscopy before radiotherapy in the treatment of Hodgkin's disease
18. Laparoscopic unilateral ovarian transposition prior to irradiation: Prospective study of 20 cases
19. Laparoscopic ovarian transposition
20. Ultrastructure of human ovarian primordial follicles after combination chemotherapy for Hodgkin's disease
21. Delayed effect of radiation therapy with or without chemotherapy on ovarian function in women with Hodgkin's disease
22. Oophoropexy and the management of Hodgkin's disease. A re-evaluation of the risks and benefits
23. Menstrual and reproductive function after treatment with combination chemotherapy for malignant ovarian germ cell tumors
24. Impact of congenital hypogonadotropism on the radiation sensitivity of the mouse ovary
25. Reproductive status in long-term bone marrow transplant survivors receiving busulfan-cyclophosphamide (120 mg/kg)
26. An evaluation of lateral and medial transposition of the ovaries out of radiation fields
27. Morphological study of the ovaries of leukaemic children
28. Gonadal damage from chemotherapy and radiotherapy
29. Efficacy and toxicity of multi agent chemotherapy and low-dose involved-field radiotherapy in children and adolescents with Hodgkin's disease
30. Early high dose chemotherapy intensification with autologous bone marrow transplantation in lymphoma associated with retention of fertility and normal pregnancies in females
31. The risk of premature menopause induced by chemotherapy for early breast cancer
32. The effects of gonadal irradiation in clinical radiation therapy: A review
33. Structural and ultrastructural study of the ovary in childhood leukemia after successful treatment
34. Ovarian injury and modern options to persevere fertility in female cancer patients treated with high dose radio-chemotherapy for hemato-oncological neoplasias and other cancers
35. Ovarian failure post chemotherapy in young cancer patients- risk assessment indicate the need for intervention
36. An in-vitro study of the effects of chemotherapy on human primordial follicles
37. Subclinical depletion of primordial follicular reserve in mice treated with cyclophosphamide: Clinical importance and proposed accurate investigative tool
38. Administration of cyclophosphamide at different stages of follicular maturation in mice: Effects on reproductive performance and fetal malformations
39. Risk factors for ovarian failure in patients with systemic lupus erythematosus receiving cyclophosphamide therapy
40. Gonadal protection and fecundity rates in cyclophosphamide-treated rats
41. Following Treatment for Breast Cancer. The incidence of treatment-related amenorrhea is related to patient age and to the treatment regimen
42. Ovarian transposition for patients with cervical carcinoma treated by radiosurgical combination
43. Identification of potassium-dependent and -independent components of the apoptotic machinery in mouse ovarian germ cells and granulosa cells
44. Cancer treatment: The last 25 years
45. Transplantation in reproductive medicine: Previous experience, present knowledge and future prospects
46. Apoptosis-associated signalling pathways are required for chemotherapy-mediated female germ cell destruction
47. Identification of potassium-dependent and -independent components of the apoptotic machinery in mouse ovarian germ cells and granulosa cells
48. Ovarian function following marrow transplantation for aplastic anemia or leukemia
49. Pregnancies following high dose cyclophosphamid with or without high dose busulfan or total body irradiation and bone marrow transplant
50. Ovarian function after autologous bone marrow transplantation in childhood: High-dose busulfan is a major cause of ovarian failure
51. Ovarian function after bone marrow transplantation during childhood
52. Laparoscopic ovarian suspension before irradiation
53. Ovarian failure following ovarian irradiation in childhood. The radiosensitivity of human oocyte
54. Ovarian function following the treatment of childhood acute lymphoblastic leukaemia
55. The effect of combination chemotherapy on ovarian function in women treated for Hodgkin's disease
56. Laparoscopic oophoropexy and ovarian function in the treatment of Hodgkin disease