Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity

Journal of Biological Chemistry

Volumn 288, Issue 46, 2013, Pages 33312-33322

  Merrins, Matthew J ^a   Van Dyke, Aaron R ^b   Mapp, Anna K ^c   Rizzo, Megan A ^c   Satin, Leslie S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSENSORS; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; ENERGY TRANSFER; ENZYMES; FEEDBACK; FORSTER RESONANCE ENERGY TRANSFER; PATHOLOGY; REDOX REACTIONS;

BISPHOSPHATES; BLOOD GLUCOSE; DIRECT MEASUREMENT; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLYCOLYTIC ENZYME; MEASUREMENTS OF; METABOLIC OSCILLATIONS; PANCREATIC ISLET; PHOSPHOFRUCTOKINASE; PYRUVATE KINASE;

GLUCOSE;

PYRUVATE KINASE; PYRUVATE KINASE M2; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; ENZYMIC BIOSENSOR; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLYCOLYSIS; MALE; METABOLITE; MOUSE; NONHUMAN; OLIGOMERIZATION; OSCILLATION; OXIDATION REDUCTION POTENTIAL; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84887837739     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.508127     Document Type: Article

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